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    NELFCD negative elongation factor complex member C/D [ Canis lupus familiaris (dog) ]

    Gene ID: 477276, updated on 17-Aug-2024

    Summary

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    Official Symbol
    NELFCDprovided by VGNC
    Official Full Name
    negative elongation factor complex member C/Dprovided by VGNC
    Primary source
    VGNC:VGNC:43738
    See related
    Ensembl:ENSCAFG00845013969
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Also known as
    TH1L
    Orthologs
    human mouse all
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    Genomic context

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    See NELFCD in Genome Data Viewer
    Location:
    chromosome: 24
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 24 NC_051828.1 (44596768..44609381)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 24 NC_006606.4 (42976753..42989365)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 24 NC_049245.1 (44478807..44491418)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 24 NC_049284.1 (43700324..43712935)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 24 NC_049765.1 (43819006..43831619)

    Chromosome 24 - NC_051828.1Genomic Context describing neighboring genes Neighboring gene GNAS complex locus Neighboring gene uncharacterized LOC119865708 Neighboring gene phosphorylated adapter RNA export protein-like Neighboring gene cathepsin Z Neighboring gene tubulin beta 1 class VI

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of transcription elongation by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of NELF complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    negative elongation factor C/D
    Names
    TH1-like
    negative elongation factor D-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051828.1 Reference ROS_Cfam_1.0

      Range
      44596768..44609381
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038434232.1 → XP_038290160.1  negative elongation factor C/D isoform X1

      UniProtKB/TrEMBL
      A0A8C0NVS8, A0A8C0R5P8, A0A8C0T9G8, A0A8I3NUK3, A0A8I3NUN8
      Related
      ENSCAFP00845019648.1, ENSCAFT00845024978.1
      Conserved Domains (1) summary
      pfam04858
      Location:22 → 598
      TH1; TH1 protein

    2. XM_038434234.1 → XP_038290162.1  negative elongation factor C/D isoform X3

      UniProtKB/TrEMBL
      A0A8C0NVS8, A0A8I3NUN8
      Conserved Domains (1) summary
      pfam04858
      Location:22 → 597
      TH1; TH1 protein

    3. XM_038434233.1 → XP_038290161.1  negative elongation factor C/D isoform X2

      UniProtKB/TrEMBL
      A0A8C0NVS8, A0A8I3NUN8
      Conserved Domains (1) summary
      pfam04858
      Location:22 → 597
      TH1; TH1 protein

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049284.1 Alternate UMICH_Zoey_3.1

      Range
      43700324..43712935
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038509389.1 → XP_038365317.1  negative elongation factor C/D isoform X1

      Conserved Domains (1) summary
      pfam04858
      Location:22 → 598
      TH1; TH1 protein

    2. XM_038509392.1 → XP_038365320.1  negative elongation factor C/D isoform X3

      Conserved Domains (1) summary
      pfam04858
      Location:22 → 597
      TH1; TH1 protein

    3. XM_038509391.1 → XP_038365319.1  negative elongation factor C/D isoform X2

      Conserved Domains (1) summary
      pfam04858
      Location:22 → 597
      TH1; TH1 protein

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049765.1 Alternate UNSW_CanFamBas_1.0

      Range
      43819006..43831619
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038637013.1 → XP_038492941.1  negative elongation factor C/D isoform X1

      Conserved Domains (1) summary
      pfam04858
      Location:22 → 598
      TH1; TH1 protein

    2. XM_038637015.1 → XP_038492943.1  negative elongation factor C/D isoform X3

      Conserved Domains (1) summary
      pfam04858
      Location:22 → 597
      TH1; TH1 protein

    3. XM_038637014.1 → XP_038492942.1  negative elongation factor C/D isoform X2

      Conserved Domains (1) summary
      pfam04858
      Location:22 → 597
      TH1; TH1 protein

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049245.1 Alternate UU_Cfam_GSD_1.0

      Range
      44478807..44491418
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038572734.1 → XP_038428662.1  negative elongation factor C/D isoform X1

      UniProtKB/TrEMBL
      A0A8C0NVS8, A0A8C0R5P8, A0A8C0T9G8, A0A8I3NUK3, A0A8I3NUN8
      Conserved Domains (1) summary
      pfam04858
      Location:22 → 598
      TH1; TH1 protein

    2. XM_038572736.1 → XP_038428664.1  negative elongation factor C/D isoform X3

      UniProtKB/TrEMBL
      A0A8C0NVS8, A0A8I3NUN8
      Conserved Domains (1) summary
      pfam04858
      Location:22 → 597
      TH1; TH1 protein

    3. XM_038572735.1 → XP_038428663.1  negative elongation factor C/D isoform X2

      UniProtKB/TrEMBL
      A0A8C0NVS8, A0A8I3NUN8
      Conserved Domains (1) summary
      pfam04858
      Location:22 → 597
      TH1; TH1 protein

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006606.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      42976753..42989365
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038457727.1 → XP_038313655.1  negative elongation factor C/D isoform X1

      UniProtKB/TrEMBL
      A0A8C0NVS8, A0A8C0R5P8, A0A8C0T9G8, A0A8I3NUK3, A0A8I3NUN8
      Conserved Domains (1) summary
      pfam04858
      Location:22 → 598
      TH1; TH1 protein

    2. XM_038457729.1 → XP_038313657.1  negative elongation factor C/D isoform X3

      UniProtKB/TrEMBL
      A0A8C0NVS8, A0A8I3NUN8
      Conserved Domains (1) summary
      pfam04858
      Location:22 → 597
      TH1; TH1 protein

    3. XM_038457728.1 → XP_038313656.1  negative elongation factor C/D isoform X2

      UniProtKB/TrEMBL
      A0A8C0NVS8, A0A8I3NUN8
      Conserved Domains (1) summary
      pfam04858
      Location:22 → 597
      TH1; TH1 protein
    Nucleotide Protein
    Heading Accession and Version

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