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    TRIM3 tripartite motif containing 3 [ Canis lupus familiaris (dog) ]

    Gene ID: 476834, updated on 17-Aug-2024

    Summary

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    Official Symbol
    TRIM3provided by VGNC
    Official Full Name
    tripartite motif containing 3provided by VGNC
    Primary source
    VGNC:VGNC:47813
    See related
    Ensembl:ENSCAFG00845008173
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See TRIM3 in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 21 NC_051825.1 (30592205..30617117, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 21 NC_006603.4 (29467945..29492844, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 21 NC_049242.1 (30274212..30299108, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 21 NC_049281.1 (29913100..29937976, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 21 NC_049762.1 (30078929..30103828, complement)

    Chromosome 21 - NC_051825.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102156231 Neighboring gene hemopexin Neighboring gene ADP ribosylation factor interacting protein 2 Neighboring gene translocase of inner mitochondrial membrane 10B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables translation repressor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of translation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein polyubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tripartite motif-containing protein 3
    XP_038286279.1
    XP_038286280.1
    XP_038312446.1
    XP_038312447.1
    XP_038361617.1
    XP_038361618.1
    XP_038424827.1
    XP_038424828.1
    XP_038488993.1
    XP_038488994.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051825.1 Reference ROS_Cfam_1.0

      Range
      30592205..30617117 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038430351.1 → XP_038286279.1  tripartite motif-containing protein 3

      UniProtKB/TrEMBL
      A0A8C0K9C5, A0A8C0RF81, A0A8I3RVW6
      Related
      ENSCAFP00845011134.1, ENSCAFT00845014376.1
      Conserved Domains (5) summary
      smart00502
      Location:158 → 284
      BBC; B-Box C-terminal domain
      smart00557
      Location:322 → 419
      IG_FLMN; Filamin-type immunoglobulin domains
      cd14960
      Location:471 → 744
      NHL_TRIM2_like; NHL repeat domain of the tripartite motif-containing protein 2 (TRIM2) and related proteins
      cd16768
      Location:19 → 63
      RING-HC_TRIM3; RING finger, HC subclass, found in tripartite motif-containing protein 3 (TRIM3)
      cd19825
      Location:107 → 153
      Bbox2_TRIM3_C-VII; B-box-type 2 zinc finger found in tripartite motif-containing protein 3 (TRIM3)

    2. XM_038430352.1 → XP_038286280.1  tripartite motif-containing protein 3

      UniProtKB/TrEMBL
      A0A8C0K9C5, A0A8C0RF81, A0A8I3RVW6
      Conserved Domains (5) summary
      smart00502
      Location:158 → 284
      BBC; B-Box C-terminal domain
      smart00557
      Location:322 → 419
      IG_FLMN; Filamin-type immunoglobulin domains
      cd14960
      Location:471 → 744
      NHL_TRIM2_like; NHL repeat domain of the tripartite motif-containing protein 2 (TRIM2) and related proteins
      cd16768
      Location:19 → 63
      RING-HC_TRIM3; RING finger, HC subclass, found in tripartite motif-containing protein 3 (TRIM3)
      cd19825
      Location:107 → 153
      Bbox2_TRIM3_C-VII; B-box-type 2 zinc finger found in tripartite motif-containing protein 3 (TRIM3)

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049281.1 Alternate UMICH_Zoey_3.1

      Range
      29913100..29937976 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038505689.1 → XP_038361617.1  tripartite motif-containing protein 3

      Conserved Domains (5) summary
      smart00502
      Location:158 → 284
      BBC; B-Box C-terminal domain
      smart00557
      Location:322 → 419
      IG_FLMN; Filamin-type immunoglobulin domains
      cd14960
      Location:471 → 744
      NHL_TRIM2_like; NHL repeat domain of the tripartite motif-containing protein 2 (TRIM2) and related proteins
      cd16768
      Location:19 → 63
      RING-HC_TRIM3; RING finger, HC subclass, found in tripartite motif-containing protein 3 (TRIM3)
      cd19825
      Location:107 → 153
      Bbox2_TRIM3_C-VII; B-box-type 2 zinc finger found in tripartite motif-containing protein 3 (TRIM3)

    2. XM_038505690.1 → XP_038361618.1  tripartite motif-containing protein 3

      Conserved Domains (5) summary
      smart00502
      Location:158 → 284
      BBC; B-Box C-terminal domain
      smart00557
      Location:322 → 419
      IG_FLMN; Filamin-type immunoglobulin domains
      cd14960
      Location:471 → 744
      NHL_TRIM2_like; NHL repeat domain of the tripartite motif-containing protein 2 (TRIM2) and related proteins
      cd16768
      Location:19 → 63
      RING-HC_TRIM3; RING finger, HC subclass, found in tripartite motif-containing protein 3 (TRIM3)
      cd19825
      Location:107 → 153
      Bbox2_TRIM3_C-VII; B-box-type 2 zinc finger found in tripartite motif-containing protein 3 (TRIM3)

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049762.1 Alternate UNSW_CanFamBas_1.0

      Range
      30078929..30103828 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038633065.1 → XP_038488993.1  tripartite motif-containing protein 3

      Conserved Domains (5) summary
      smart00502
      Location:158 → 284
      BBC; B-Box C-terminal domain
      smart00557
      Location:322 → 419
      IG_FLMN; Filamin-type immunoglobulin domains
      cd14960
      Location:471 → 744
      NHL_TRIM2_like; NHL repeat domain of the tripartite motif-containing protein 2 (TRIM2) and related proteins
      cd16768
      Location:19 → 63
      RING-HC_TRIM3; RING finger, HC subclass, found in tripartite motif-containing protein 3 (TRIM3)
      cd19825
      Location:107 → 153
      Bbox2_TRIM3_C-VII; B-box-type 2 zinc finger found in tripartite motif-containing protein 3 (TRIM3)

    2. XM_038633066.1 → XP_038488994.1  tripartite motif-containing protein 3

      Conserved Domains (5) summary
      smart00502
      Location:158 → 284
      BBC; B-Box C-terminal domain
      smart00557
      Location:322 → 419
      IG_FLMN; Filamin-type immunoglobulin domains
      cd14960
      Location:471 → 744
      NHL_TRIM2_like; NHL repeat domain of the tripartite motif-containing protein 2 (TRIM2) and related proteins
      cd16768
      Location:19 → 63
      RING-HC_TRIM3; RING finger, HC subclass, found in tripartite motif-containing protein 3 (TRIM3)
      cd19825
      Location:107 → 153
      Bbox2_TRIM3_C-VII; B-box-type 2 zinc finger found in tripartite motif-containing protein 3 (TRIM3)

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049242.1 Alternate UU_Cfam_GSD_1.0

      Range
      30274212..30299108 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038568899.1 → XP_038424827.1  tripartite motif-containing protein 3

      UniProtKB/TrEMBL
      A0A8C0K9C5, A0A8C0RF81, A0A8I3RVW6
      Conserved Domains (5) summary
      smart00502
      Location:158 → 284
      BBC; B-Box C-terminal domain
      smart00557
      Location:322 → 419
      IG_FLMN; Filamin-type immunoglobulin domains
      cd14960
      Location:471 → 744
      NHL_TRIM2_like; NHL repeat domain of the tripartite motif-containing protein 2 (TRIM2) and related proteins
      cd16768
      Location:19 → 63
      RING-HC_TRIM3; RING finger, HC subclass, found in tripartite motif-containing protein 3 (TRIM3)
      cd19825
      Location:107 → 153
      Bbox2_TRIM3_C-VII; B-box-type 2 zinc finger found in tripartite motif-containing protein 3 (TRIM3)

    2. XM_038568900.1 → XP_038424828.1  tripartite motif-containing protein 3

      UniProtKB/TrEMBL
      A0A8C0K9C5, A0A8C0RF81, A0A8I3RVW6
      Conserved Domains (5) summary
      smart00502
      Location:158 → 284
      BBC; B-Box C-terminal domain
      smart00557
      Location:322 → 419
      IG_FLMN; Filamin-type immunoglobulin domains
      cd14960
      Location:471 → 744
      NHL_TRIM2_like; NHL repeat domain of the tripartite motif-containing protein 2 (TRIM2) and related proteins
      cd16768
      Location:19 → 63
      RING-HC_TRIM3; RING finger, HC subclass, found in tripartite motif-containing protein 3 (TRIM3)
      cd19825
      Location:107 → 153
      Bbox2_TRIM3_C-VII; B-box-type 2 zinc finger found in tripartite motif-containing protein 3 (TRIM3)

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006603.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      29467945..29492844 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038456518.1 → XP_038312446.1  tripartite motif-containing protein 3

      UniProtKB/TrEMBL
      A0A8C0K9C5, A0A8C0RF81, A0A8I3RVW6
      Conserved Domains (5) summary
      smart00502
      Location:158 → 284
      BBC; B-Box C-terminal domain
      smart00557
      Location:322 → 419
      IG_FLMN; Filamin-type immunoglobulin domains
      cd14960
      Location:471 → 744
      NHL_TRIM2_like; NHL repeat domain of the tripartite motif-containing protein 2 (TRIM2) and related proteins
      cd16768
      Location:19 → 63
      RING-HC_TRIM3; RING finger, HC subclass, found in tripartite motif-containing protein 3 (TRIM3)
      cd19825
      Location:107 → 153
      Bbox2_TRIM3_C-VII; B-box-type 2 zinc finger found in tripartite motif-containing protein 3 (TRIM3)

    2. XM_038456519.1 → XP_038312447.1  tripartite motif-containing protein 3

      UniProtKB/TrEMBL
      A0A8C0K9C5, A0A8C0RF81, A0A8I3RVW6
      Conserved Domains (5) summary
      smart00502
      Location:158 → 284
      BBC; B-Box C-terminal domain
      smart00557
      Location:322 → 419
      IG_FLMN; Filamin-type immunoglobulin domains
      cd14960
      Location:471 → 744
      NHL_TRIM2_like; NHL repeat domain of the tripartite motif-containing protein 2 (TRIM2) and related proteins
      cd16768
      Location:19 → 63
      RING-HC_TRIM3; RING finger, HC subclass, found in tripartite motif-containing protein 3 (TRIM3)
      cd19825
      Location:107 → 153
      Bbox2_TRIM3_C-VII; B-box-type 2 zinc finger found in tripartite motif-containing protein 3 (TRIM3)
    Nucleotide Protein
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