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    U2AF1L4 U2 small nuclear RNA auxiliary factor 1 like 4 [ Canis lupus familiaris (dog) ]

    Gene ID: 476480, updated on 17-Aug-2024

    Summary

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    Official Symbol
    U2AF1L4provided by VGNC
    Official Full Name
    U2 small nuclear RNA auxiliary factor 1 like 4provided by VGNC
    Primary source
    VGNC:VGNC:58341
    See related
    Ensembl:ENSCAFG00845001465
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Also known as
    TMEM149
    Orthologs
    human mouse all
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    Genomic context

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    See U2AF1L4 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 1 NC_051805.1 (117491646..117493887)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 1 NC_006583.4 (116293931..116296172)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 1 NC_049222.1 (117734028..117736264)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 1 NC_049261.1 (117055022..117057262)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 1 NC_049742.1 (116678643..116680884)

    Chromosome 1 - NC_051805.1Genomic Context describing neighboring genes Neighboring gene lin-37 DREAM MuvB core complex component Neighboring gene presenilin enhancer, gamma-secretase subunit Neighboring gene IGF like family receptor 1 Neighboring gene lysine methyltransferase 2B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables pre-mRNA 3'-splice site binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mRNA splicing, via spliceosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of U2AF complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of spliceosomal complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    splicing factor U2AF 26 kDa subunit
    Names
    transmembrane protein 149

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051805.1 Reference ROS_Cfam_1.0

      Range
      117491646..117493887
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038657395.1 → XP_038513323.1  splicing factor U2AF 26 kDa subunit isoform X1

      UniProtKB/TrEMBL
      A0A8C0L1E7, A0A8C0Z3X2
      Conserved Domains (2) summary
      pfam00642
      Location:149 → 175
      zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
      cd12538
      Location:43 → 146
      RRM_U2AF35; RNA recognition motif (RRM) found in U2 small nuclear ribonucleoprotein auxiliary factor U2AF 35 kDa subunit (U2AF35)

    2. XM_038657396.1 → XP_038513324.1  splicing factor U2AF 26 kDa subunit isoform X2

      Conserved Domains (2) summary
      pfam00642
      Location:13 → 39
      zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
      cl17169
      Location:41 → 107
      RRM_SF; RNA recognition motif (RRM) superfamily

    3. XM_038657397.1 → XP_038513325.1  splicing factor U2AF 26 kDa subunit isoform X3

      UniProtKB/TrEMBL
      A0A8C0L1S6, A0A8C0TDU3, A0A8I3MYY4
      Related
      ENSCAFP00845001989.1, ENSCAFT00845002502.1
      Conserved Domains (2) summary
      pfam00642
      Location:110 → 136
      zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
      cl17169
      Location:41 → 107
      RRM_SF; RNA recognition motif (RRM) superfamily

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049261.1 Alternate UMICH_Zoey_3.1

      Range
      117055022..117057262
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038468511.1 → XP_038324439.1  splicing factor U2AF 26 kDa subunit isoform X1

      Conserved Domains (2) summary
      pfam00642
      Location:149 → 175
      zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
      cd12538
      Location:43 → 146
      RRM_U2AF35; RNA recognition motif (RRM) found in U2 small nuclear ribonucleoprotein auxiliary factor U2AF 35 kDa subunit (U2AF35)

    2. XM_038468512.1 → XP_038324440.1  splicing factor U2AF 26 kDa subunit isoform X2

      Conserved Domains (2) summary
      pfam00642
      Location:13 → 39
      zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
      cl17169
      Location:41 → 107
      RRM_SF; RNA recognition motif (RRM) superfamily

    3. XM_038468513.1 → XP_038324441.1  splicing factor U2AF 26 kDa subunit isoform X3

      Conserved Domains (2) summary
      pfam00642
      Location:110 → 136
      zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
      cl17169
      Location:41 → 107
      RRM_SF; RNA recognition motif (RRM) superfamily

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049742.1 Alternate UNSW_CanFamBas_1.0

      Range
      116678643..116680884
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038593541.1 → XP_038449469.1  splicing factor U2AF 26 kDa subunit isoform X1

      Conserved Domains (2) summary
      pfam00642
      Location:149 → 175
      zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
      cd12538
      Location:43 → 146
      RRM_U2AF35; RNA recognition motif (RRM) found in U2 small nuclear ribonucleoprotein auxiliary factor U2AF 35 kDa subunit (U2AF35)

    2. XM_038593542.1 → XP_038449470.1  splicing factor U2AF 26 kDa subunit isoform X2

      Conserved Domains (2) summary
      pfam00642
      Location:13 → 39
      zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
      cl17169
      Location:41 → 107
      RRM_SF; RNA recognition motif (RRM) superfamily

    3. XM_038593543.1 → XP_038449471.1  splicing factor U2AF 26 kDa subunit isoform X3

      Conserved Domains (2) summary
      pfam00642
      Location:110 → 136
      zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
      cl17169
      Location:41 → 107
      RRM_SF; RNA recognition motif (RRM) superfamily

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049222.1 Alternate UU_Cfam_GSD_1.0

      Range
      117734028..117736264
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038529284.1 → XP_038385212.1  splicing factor U2AF 26 kDa subunit isoform X1

      UniProtKB/TrEMBL
      A0A8C0L1E7, A0A8C0Z3X2
      Conserved Domains (2) summary
      pfam00642
      Location:149 → 175
      zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
      cd12538
      Location:43 → 146
      RRM_U2AF35; RNA recognition motif (RRM) found in U2 small nuclear ribonucleoprotein auxiliary factor U2AF 35 kDa subunit (U2AF35)

    2. XM_038529285.1 → XP_038385213.1  splicing factor U2AF 26 kDa subunit isoform X2

      Conserved Domains (2) summary
      pfam00642
      Location:13 → 39
      zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
      cl17169
      Location:41 → 107
      RRM_SF; RNA recognition motif (RRM) superfamily

    3. XM_038529286.1 → XP_038385214.1  splicing factor U2AF 26 kDa subunit isoform X3

      UniProtKB/TrEMBL
      A0A8C0L1S6, A0A8C0TDU3, A0A8I3MYY4
      Conserved Domains (2) summary
      pfam00642
      Location:110 → 136
      zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
      cl17169
      Location:41 → 107
      RRM_SF; RNA recognition motif (RRM) superfamily

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006583.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      116293931..116296172
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005616693.4 → XP_005616750.1  splicing factor U2AF 26 kDa subunit isoform X1

      See identical proteins and their annotated locations for XP_005616750.1

      UniProtKB/TrEMBL
      A0A8C0L1E7, A0A8C0Z3X2
      Conserved Domains (2) summary
      pfam00642
      Location:149 → 175
      zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
      cd12538
      Location:43 → 146
      RRM_U2AF35; RNA recognition motif (RRM) found in U2 small nuclear ribonucleoprotein auxiliary factor U2AF 35 kDa subunit (U2AF35)

    2. XM_038453018.1 → XP_038308946.1  splicing factor U2AF 26 kDa subunit isoform X2

      Conserved Domains (2) summary
      pfam00642
      Location:13 → 39
      zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
      cl17169
      Location:41 → 107
      RRM_SF; RNA recognition motif (RRM) superfamily

    3. XM_038453021.1 → XP_038308949.1  splicing factor U2AF 26 kDa subunit isoform X3

      UniProtKB/TrEMBL
      A0A8C0L1S6, A0A8C0TDU3, A0A8I3MYY4
      Conserved Domains (2) summary
      pfam00642
      Location:110 → 136
      zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
      cl17169
      Location:41 → 107
      RRM_SF; RNA recognition motif (RRM) superfamily
    Nucleotide Protein
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