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    MCM6 minichromosome maintenance complex component 6 [ Canis lupus familiaris (dog) ]

    Gene ID: 476131, updated on 17-Aug-2024

    Summary

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    Official Symbol
    MCM6provided by VGNC
    Official Full Name
    minichromosome maintenance complex component 6provided by VGNC
    Primary source
    VGNC:VGNC:43086
    See related
    Ensembl:ENSCAFG00845009951
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See MCM6 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 19 NC_051823.1 (40072481..40105667, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 19 NC_006601.4 (38870097..38903283, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 19 NC_049240.1 (40106781..40139971, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 19 NC_049279.1 (38714459..38747626, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 19 NC_049760.1 (38874063..38907654, complement)

    Chromosome 19 - NC_051823.1Genomic Context describing neighboring genes Neighboring gene UBX domain protein 4 Neighboring gene lactase Neighboring gene small nucleolar SNORD12/SNORD106 Neighboring gene aspartyl-tRNA synthetase 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables single-stranded 3'-5' DNA helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables single-stranded DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA replication initiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in DNA unwinding involved in DNA replication IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in double-strand break repair via break-induced replication IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in mitotic DNA replication IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of MCM complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DNA replication licensing factor MCM6
    XP_038282108.1
    XP_038358307.1
    XP_038421022.1
    XP_038485114.1
    XP_533338.3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051823.1 Reference ROS_Cfam_1.0

      Range
      40072481..40105667 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038426180.1 → XP_038282108.1  DNA replication licensing factor MCM6

      UniProtKB/TrEMBL
      A0A8C0KSH9, A0A8C0NN33, A0A8I3N2T8, A0A8I3N8N4, A0A8P0TT05
      Related
      ENSCAFP00845013615.1, ENSCAFT00845017492.1
      Conserved Domains (3) summary
      smart00350
      Location:119 → 657
      MCM; minichromosome maintenance proteins
      pfam14551
      Location:27 → 114
      MCM_N; MCM N-terminal domain
      pfam18263
      Location:713 → 817
      MCM6_C; MCM6 C-terminal winged-helix domain

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049279.1 Alternate UMICH_Zoey_3.1

      Range
      38714459..38747626 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038502379.1 → XP_038358307.1  DNA replication licensing factor MCM6

      Conserved Domains (3) summary
      smart00350
      Location:119 → 657
      MCM; minichromosome maintenance proteins
      pfam14551
      Location:27 → 114
      MCM_N; MCM N-terminal domain
      pfam18263
      Location:713 → 817
      MCM6_C; MCM6 C-terminal winged-helix domain

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049760.1 Alternate UNSW_CanFamBas_1.0

      Range
      38874063..38907654 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038629186.1 → XP_038485114.1  DNA replication licensing factor MCM6

      Conserved Domains (3) summary
      smart00350
      Location:119 → 657
      MCM; minichromosome maintenance proteins
      pfam14551
      Location:27 → 114
      MCM_N; MCM N-terminal domain
      pfam18263
      Location:713 → 817
      MCM6_C; MCM6 C-terminal winged-helix domain

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049240.1 Alternate UU_Cfam_GSD_1.0

      Range
      40106781..40139971 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038565094.1 → XP_038421022.1  DNA replication licensing factor MCM6

      UniProtKB/TrEMBL
      A0A8C0KSH9, A0A8C0NN33, A0A8I3N2T8, A0A8I3N8N4, A0A8P0TT05
      Conserved Domains (3) summary
      smart00350
      Location:119 → 657
      MCM; minichromosome maintenance proteins
      pfam14551
      Location:27 → 114
      MCM_N; MCM N-terminal domain
      pfam18263
      Location:713 → 817
      MCM6_C; MCM6 C-terminal winged-helix domain

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006601.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      38870097..38903283 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_533338.7 → XP_533338.3  DNA replication licensing factor MCM6

      UniProtKB/TrEMBL
      A0A8C0KSH9, A0A8C0NN33, A0A8I3N2T8, A0A8I3N8N4, A0A8P0TT05
      Conserved Domains (3) summary
      smart00350
      Location:119 → 657
      MCM; minichromosome maintenance proteins
      pfam14551
      Location:27 → 114
      MCM_N; MCM N-terminal domain
      pfam18263
      Location:713 → 817
      MCM6_C; MCM6 C-terminal winged-helix domain
    Nucleotide Protein
    Heading Accession and Version

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