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    AMPH amphiphysin [ Canis lupus familiaris (dog) ]

    Gene ID: 475877, updated on 17-Aug-2024

    Summary

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    Official Symbol
    AMPHprovided by VGNC
    Official Full Name
    amphiphysinprovided by VGNC
    Primary source
    VGNC:VGNC:37840
    See related
    Ensembl:ENSCAFG00845020583
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See AMPH in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 18 NC_051822.1 (11099548..11310938)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 18 NC_006600.4 (10903625..11114792)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 18 NC_049239.1 (11160063..11371410)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 18 NC_049278.1 (11076355..11287485)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 18 NC_049759.1 (11044639..11263972)

    Chromosome 18 - NC_051822.1Genomic Context describing neighboring genes Neighboring gene U2 spliceosomal RNA Neighboring gene uncharacterized LOC111090882 Neighboring gene uncharacterized LOC111090883 Neighboring gene uncharacterized LOC102154161 Neighboring gene T-cell receptor gamma chain C region Neighboring gene T cell receptor gamma constant 2-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables phospholipid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in synaptic vesicle endocytosis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in synaptic vesicle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    LOW QUALITY PROTEIN: amphiphysin; amphiphysin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051822.1 Reference ROS_Cfam_1.0

      Range
      11099548..11310938
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038423729.1 → XP_038279657.1  amphiphysin isoform X3

      UniProtKB/TrEMBL
      A0A8C0S6D3, A0A8I3P724
      Related
      ENSCAFP00845029229.1, ENSCAFT00845037318.1
      Conserved Domains (3) summary
      cd07611
      Location:26 → 236
      BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
      cd12140
      Location:552 → 623
      SH3_Amphiphysin_I; Src Homology 3 domain of Amphiphysin I
      PRK14951
      Location:435 → 573
      PRK14951; DNA polymerase III subunits gamma and tau; Provisional

    2. XM_038423727.1 → XP_038279655.1  amphiphysin isoform X1

      UniProtKB/TrEMBL
      A0A8C0S6B5, A0A8I3S229
      Related
      ENSCAFP00845028986.1, ENSCAFT00845037017.1
      Conserved Domains (3) summary
      cd07611
      Location:26 → 236
      BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
      cd12140
      Location:613 → 684
      SH3_Amphiphysin_I; Src Homology 3 domain of Amphiphysin I
      PRK07003
      Location:446 → 611
      PRK07003; DNA polymerase III subunit gamma/tau

    3. XM_038423728.1 → XP_038279656.1  amphiphysin isoform X2

      UniProtKB/TrEMBL
      A0A8C0S6D3
      Conserved Domains (3) summary
      cd07611
      Location:26 → 236
      BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
      cd12140
      Location:571 → 642
      SH3_Amphiphysin_I; Src Homology 3 domain of Amphiphysin I
      PRK14951
      Location:454 → 592
      PRK14951; DNA polymerase III subunits gamma and tau; Provisional

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049278.1 Alternate UMICH_Zoey_3.1

      Range
      11076355..11287485
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038500086.1 → XP_038356014.1  LOW QUALITY PROTEIN: amphiphysin isoform X4

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049759.1 Alternate UNSW_CanFamBas_1.0

      Range
      11044639..11263972
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038626754.1 → XP_038482682.1  amphiphysin isoform X2

      Conserved Domains (3) summary
      cd07611
      Location:26 → 236
      BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
      cd12140
      Location:571 → 642
      SH3_Amphiphysin_I; Src Homology 3 domain of Amphiphysin I
      PRK14951
      Location:454 → 592
      PRK14951; DNA polymerase III subunits gamma and tau; Provisional

    2. XM_038626755.1 → XP_038482683.1  amphiphysin isoform X3

      Conserved Domains (3) summary
      cd07611
      Location:26 → 236
      BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
      cd12140
      Location:552 → 623
      SH3_Amphiphysin_I; Src Homology 3 domain of Amphiphysin I
      PRK14951
      Location:435 → 573
      PRK14951; DNA polymerase III subunits gamma and tau; Provisional

    3. XM_038626753.1 → XP_038482681.1  amphiphysin isoform X1

      Conserved Domains (3) summary
      cd07611
      Location:26 → 236
      BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
      cd12140
      Location:613 → 684
      SH3_Amphiphysin_I; Src Homology 3 domain of Amphiphysin I
      PRK07003
      Location:446 → 611
      PRK07003; DNA polymerase III subunit gamma/tau

    4. XM_038626756.1 → XP_038482684.1  amphiphysin isoform X5

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049239.1 Alternate UU_Cfam_GSD_1.0

      Range
      11160063..11371410
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038562674.1 → XP_038418602.1  amphiphysin isoform X8

      UniProtKB/TrEMBL
      A0A8C0S6D3, A0A8I3P724
      Conserved Domains (3) summary
      cd07611
      Location:26 → 236
      BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
      cd12140
      Location:552 → 623
      SH3_Amphiphysin_I; Src Homology 3 domain of Amphiphysin I
      PRK14951
      Location:435 → 573
      PRK14951; DNA polymerase III subunits gamma and tau; Provisional

    2. XM_038562672.1 → XP_038418600.1  amphiphysin isoform X6

      UniProtKB/TrEMBL
      A0A8C0S6B5, A0A8I3S229
      Conserved Domains (3) summary
      cd07611
      Location:26 → 236
      BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
      cd12140
      Location:613 → 684
      SH3_Amphiphysin_I; Src Homology 3 domain of Amphiphysin I
      PRK07003
      Location:446 → 611
      PRK07003; DNA polymerase III subunit gamma/tau

    3. XM_038562673.1 → XP_038418601.1  amphiphysin isoform X7

      UniProtKB/TrEMBL
      A0A8C0S6D3
      Conserved Domains (3) summary
      cd07611
      Location:26 → 236
      BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
      cd12140
      Location:571 → 642
      SH3_Amphiphysin_I; Src Homology 3 domain of Amphiphysin I
      PRK14951
      Location:454 → 592
      PRK14951; DNA polymerase III subunits gamma and tau; Provisional

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006600.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      10903625..11114792
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038454079.1 → XP_038310007.1  amphiphysin isoform X2

      UniProtKB/TrEMBL
      A0A8C0M5I3, A0A8C0S6D3
      Conserved Domains (3) summary
      cd07611
      Location:26 → 236
      BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
      cd12140
      Location:571 → 642
      SH3_Amphiphysin_I; Src Homology 3 domain of Amphiphysin I
      PRK14951
      Location:454 → 592
      PRK14951; DNA polymerase III subunits gamma and tau; Provisional

    2. XM_038454080.1 → XP_038310008.1  amphiphysin isoform X3

      UniProtKB/TrEMBL
      A0A8C0S6D3
      Conserved Domains (3) summary
      cd07611
      Location:26 → 236
      BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
      cd12140
      Location:552 → 623
      SH3_Amphiphysin_I; Src Homology 3 domain of Amphiphysin I
      PRK14951
      Location:435 → 573
      PRK14951; DNA polymerase III subunits gamma and tau; Provisional

    3. XM_038454078.1 → XP_038310006.1  amphiphysin isoform X1

      UniProtKB/TrEMBL
      A0A8C0MAI6, A0A8C0S6B5, A0A8P0T7J2
      Conserved Domains (3) summary
      cd07611
      Location:26 → 236
      BAR_Amphiphysin_I_II; The Bin/Amphiphysin/Rvs (BAR) domain of Amphiphysin I and II
      cd12140
      Location:613 → 684
      SH3_Amphiphysin_I; Src Homology 3 domain of Amphiphysin I
      PRK07003
      Location:446 → 611
      PRK07003; DNA polymerase III subunit gamma/tau
    Nucleotide Protein
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