STAR steroidogenic acute regulatory protein [Canis lupus familiaris (dog)] - Gene

Summary

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Official Symbol: STARprovided by VGNC
Official Full Name: steroidogenic acute regulatory proteinprovided by VGNC
Primary source: VGNC:VGNC:46880
See related: Ensembl:ENSCAFG00845013206
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	16	NC_051820.1 (29225542..29230211)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	16	NC_006598.4 (27843664..27848334)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	16	NC_049237.1 (28064539..28069208)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	16	NC_049276.1 (27447844..27452510)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	16	NC_049757.1 (28025113..28029783)

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

RT-PCR analysis revealed no overexpression of StAR and steroidogenic enzymes in canine cortisol-secreting adrenocortical tumors (ATs); significant downregulation of ACTH-R in carcinomas might be associated with the malignant character of the AT
Title: Expression of the ACTH receptor, steroidogenic acute regulatory protein, and steroidogenic enzymes in canine cortisol-secreting adrenocortical tumors.
Expression of the steroidogenic acute regulatory protein (StAR) in the canine corpus luteum (CL) is examined throughout the luteal phase covering the periods of CL formation, early and late regression.
Title: Molecular cloning and expression of StAR protein in the canine corpus luteum during dioestrus.

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General gene information

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Markers

MARC_35058-35059:1074713892:4 (e-PCR)
- UniSTS:471518

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables cholesterol binding	IEA Inferred from Electronic Annotation more info	PubMed
enables cholesterol transfer activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in intracellular cholesterol transport	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of steroid biosynthetic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in steroid biosynthetic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in mitochondrial intermembrane space	IEA Inferred from Electronic Annotation more info	PubMed
located_in mitochondrion	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: steroidogenic acute regulatory protein, mitochondrial

Names: steroidogenic acute regulator

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.