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    SH2D4A SH2 domain containing 4A [ Canis lupus familiaris (dog) ]

    Gene ID: 475564, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SH2D4Aprovided by VGNC
    Official Full Name
    SH2 domain containing 4Aprovided by VGNC
    Primary source
    VGNC:VGNC:46114
    See related
    Ensembl:ENSCAFG00845015986
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See SH2D4A in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 16 NC_051820.1 (23878894..23950089)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 16 NC_006598.4 (22644579..22715648)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 16 NC_049237.1 (22875425..22946531)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 16 NC_049276.1 (22237393..22308413)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 16 NC_049757.1 (22822486..22893799)

    Chromosome 16 - NC_051820.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111090270 Neighboring gene keratin, type I cytoskeletal 18-like Neighboring gene chondroitin sulfate N-acetylgalactosaminyltransferase 1 Neighboring gene keratin, type I cytoskeletal 18-like Neighboring gene integrator complex subunit 10

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables phosphatase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    SH2 domain-containing protein 4A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051820.1 Reference ROS_Cfam_1.0

      Range
      23878894..23950089
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038689648.1 → XP_038545576.1  SH2 domain-containing protein 4A isoform X1

      UniProtKB/TrEMBL
      A0A8C0JTL3, A0A8C0P111, A0A8C0YZU0, A0A8I3P6X5, A0A8P0N7Z9
      Conserved Domains (2) summary
      PTZ00121
      Location:99 → 248
      PTZ00121; MAEBL; Provisional
      cl15255
      Location:339 → 441
      SH2; Src homology 2 (SH2) domain

    2. XM_038689649.1 → XP_038545577.1  SH2 domain-containing protein 4A isoform X1

      UniProtKB/TrEMBL
      A0A8C0JTL3, A0A8C0P111, A0A8C0YZU0, A0A8I3P6X5, A0A8P0N7Z9
      Conserved Domains (2) summary
      PTZ00121
      Location:99 → 248
      PTZ00121; MAEBL; Provisional
      cl15255
      Location:339 → 441
      SH2; Src homology 2 (SH2) domain

    3. XM_038689647.1 → XP_038545575.1  SH2 domain-containing protein 4A isoform X1

      UniProtKB/TrEMBL
      A0A8C0JTL3, A0A8C0P111, A0A8C0YZU0, A0A8I3P6X5, A0A8P0N7Z9
      Related
      ENSCAFP00845022375.1, ENSCAFT00845028445.1
      Conserved Domains (2) summary
      PTZ00121
      Location:99 → 248
      PTZ00121; MAEBL; Provisional
      cl15255
      Location:339 → 441
      SH2; Src homology 2 (SH2) domain

    4. XM_038689650.1 → XP_038545578.1  SH2 domain-containing protein 4A isoform X2

      UniProtKB/TrEMBL
      A0A8C0JUZ5, A0A8C0P5W6
      Conserved Domains (2) summary
      PTZ00121
      Location:99 → 232
      PTZ00121; MAEBL; Provisional
      cl15255
      Location:312 → 414
      SH2; Src homology 2 (SH2) domain

    5. XM_038689653.1 → XP_038545581.1  SH2 domain-containing protein 4A isoform X4

      Conserved Domains (1) summary
      PTZ00121
      Location:99 → 248
      PTZ00121; MAEBL; Provisional

    6. XM_038689652.1 → XP_038545580.1  SH2 domain-containing protein 4A isoform X3

      Conserved Domains (1) summary
      PTZ00121
      Location:99 → 248
      PTZ00121; MAEBL; Provisional

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049276.1 Alternate UMICH_Zoey_3.1

      Range
      22237393..22308413
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038497431.1 → XP_038353359.1  SH2 domain-containing protein 4A isoform X1

      Conserved Domains (2) summary
      PTZ00121
      Location:99 → 248
      PTZ00121; MAEBL; Provisional
      cl15255
      Location:339 → 441
      SH2; Src homology 2 (SH2) domain

    2. XM_038497432.1 → XP_038353360.1  SH2 domain-containing protein 4A isoform X1

      Conserved Domains (2) summary
      PTZ00121
      Location:99 → 248
      PTZ00121; MAEBL; Provisional
      cl15255
      Location:339 → 441
      SH2; Src homology 2 (SH2) domain

    3. XM_038497430.1 → XP_038353358.1  SH2 domain-containing protein 4A isoform X1

      Conserved Domains (2) summary
      PTZ00121
      Location:99 → 248
      PTZ00121; MAEBL; Provisional
      cl15255
      Location:339 → 441
      SH2; Src homology 2 (SH2) domain

    4. XM_038497433.1 → XP_038353361.1  SH2 domain-containing protein 4A isoform X2

      Conserved Domains (2) summary
      PTZ00121
      Location:99 → 232
      PTZ00121; MAEBL; Provisional
      cl15255
      Location:312 → 414
      SH2; Src homology 2 (SH2) domain

    5. XM_038497435.1 → XP_038353363.1  SH2 domain-containing protein 4A isoform X4

      Conserved Domains (1) summary
      PTZ00121
      Location:99 → 248
      PTZ00121; MAEBL; Provisional

    6. XM_038497434.1 → XP_038353362.1  SH2 domain-containing protein 4A isoform X3

      Conserved Domains (1) summary
      PTZ00121
      Location:99 → 248
      PTZ00121; MAEBL; Provisional

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049757.1 Alternate UNSW_CanFamBas_1.0

      Range
      22822486..22893799
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038623884.1 → XP_038479812.1  SH2 domain-containing protein 4A isoform X1

      Conserved Domains (2) summary
      PTZ00121
      Location:99 → 248
      PTZ00121; MAEBL; Provisional
      cl15255
      Location:339 → 441
      SH2; Src homology 2 (SH2) domain

    2. XM_038623885.1 → XP_038479813.1  SH2 domain-containing protein 4A isoform X1

      Conserved Domains (2) summary
      PTZ00121
      Location:99 → 248
      PTZ00121; MAEBL; Provisional
      cl15255
      Location:339 → 441
      SH2; Src homology 2 (SH2) domain

    3. XM_038623883.1 → XP_038479811.1  SH2 domain-containing protein 4A isoform X1

      Conserved Domains (2) summary
      PTZ00121
      Location:99 → 248
      PTZ00121; MAEBL; Provisional
      cl15255
      Location:339 → 441
      SH2; Src homology 2 (SH2) domain

    4. XM_038623886.1 → XP_038479814.1  SH2 domain-containing protein 4A isoform X2

      Conserved Domains (2) summary
      PTZ00121
      Location:99 → 232
      PTZ00121; MAEBL; Provisional
      cl15255
      Location:312 → 414
      SH2; Src homology 2 (SH2) domain

    5. XM_038623889.1 → XP_038479817.1  SH2 domain-containing protein 4A isoform X4

      Conserved Domains (1) summary
      PTZ00121
      Location:99 → 248
      PTZ00121; MAEBL; Provisional

    6. XM_038623887.1 → XP_038479815.1  SH2 domain-containing protein 4A isoform X3

      Conserved Domains (1) summary
      PTZ00121
      Location:99 → 248
      PTZ00121; MAEBL; Provisional

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049237.1 Alternate UU_Cfam_GSD_1.0

      Range
      22875425..22946531
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038559860.1 → XP_038415788.1  SH2 domain-containing protein 4A isoform X1

      UniProtKB/TrEMBL
      A0A8C0JTL3, A0A8C0P111, A0A8C0YZU0, A0A8I3P6X5, A0A8P0N7Z9
      Conserved Domains (2) summary
      PTZ00121
      Location:99 → 248
      PTZ00121; MAEBL; Provisional
      cl15255
      Location:339 → 441
      SH2; Src homology 2 (SH2) domain

    2. XM_038559861.1 → XP_038415789.1  SH2 domain-containing protein 4A isoform X1

      UniProtKB/TrEMBL
      A0A8C0JTL3, A0A8C0P111, A0A8C0YZU0, A0A8I3P6X5, A0A8P0N7Z9
      Conserved Domains (2) summary
      PTZ00121
      Location:99 → 248
      PTZ00121; MAEBL; Provisional
      cl15255
      Location:339 → 441
      SH2; Src homology 2 (SH2) domain

    3. XM_038559859.1 → XP_038415787.1  SH2 domain-containing protein 4A isoform X1

      UniProtKB/TrEMBL
      A0A8C0JTL3, A0A8C0P111, A0A8C0YZU0, A0A8I3P6X5, A0A8P0N7Z9
      Conserved Domains (2) summary
      PTZ00121
      Location:99 → 248
      PTZ00121; MAEBL; Provisional
      cl15255
      Location:339 → 441
      SH2; Src homology 2 (SH2) domain

    4. XM_038559862.1 → XP_038415790.1  SH2 domain-containing protein 4A isoform X2

      UniProtKB/TrEMBL
      A0A8C0JUZ5, A0A8C0P5W6
      Conserved Domains (2) summary
      PTZ00121
      Location:99 → 232
      PTZ00121; MAEBL; Provisional
      cl15255
      Location:312 → 414
      SH2; Src homology 2 (SH2) domain

    5. XM_038559864.1 → XP_038415792.1  SH2 domain-containing protein 4A isoform X4

      Conserved Domains (1) summary
      PTZ00121
      Location:99 → 248
      PTZ00121; MAEBL; Provisional

    6. XM_038559863.1 → XP_038415791.1  SH2 domain-containing protein 4A isoform X3

      Conserved Domains (1) summary
      PTZ00121
      Location:99 → 248
      PTZ00121; MAEBL; Provisional

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006598.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      22644579..22715648
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_843127.4 → XP_848220.1  SH2 domain-containing protein 4A isoform X1

      See identical proteins and their annotated locations for XP_848220.1

      UniProtKB/TrEMBL
      A0A8C0JTL3, A0A8C0P111, A0A8C0YZU0, A0A8I3P6X5, A0A8P0N7Z9
      Conserved Domains (2) summary
      PTZ00121
      Location:99 → 248
      PTZ00121; MAEBL; Provisional
      cl15255
      Location:339 → 441
      SH2; Src homology 2 (SH2) domain

    2. XM_005629764.3 → XP_005629821.1  SH2 domain-containing protein 4A isoform X1

      See identical proteins and their annotated locations for XP_005629821.1

      UniProtKB/TrEMBL
      A0A8C0JTL3, A0A8C0P111, A0A8C0YZU0, A0A8I3P6X5, A0A8P0N7Z9
      Conserved Domains (2) summary
      PTZ00121
      Location:99 → 248
      PTZ00121; MAEBL; Provisional
      cl15255
      Location:339 → 441
      SH2; Src homology 2 (SH2) domain

    3. XM_005629763.4 → XP_005629820.1  SH2 domain-containing protein 4A isoform X1

      See identical proteins and their annotated locations for XP_005629820.1

      UniProtKB/TrEMBL
      A0A8C0JTL3, A0A8C0P111, A0A8C0YZU0, A0A8I3P6X5, A0A8P0N7Z9
      Conserved Domains (2) summary
      PTZ00121
      Location:99 → 248
      PTZ00121; MAEBL; Provisional
      cl15255
      Location:339 → 441
      SH2; Src homology 2 (SH2) domain

    4. XM_005629765.4 → XP_005629822.1  SH2 domain-containing protein 4A isoform X2

      UniProtKB/TrEMBL
      A0A8C0JUZ5, A0A8C0P5W6
      Conserved Domains (2) summary
      PTZ00121
      Location:99 → 232
      PTZ00121; MAEBL; Provisional
      cl15255
      Location:312 → 414
      SH2; Src homology 2 (SH2) domain

    5. XM_038452605.1 → XP_038308533.1  SH2 domain-containing protein 4A isoform X4

      Conserved Domains (1) summary
      PTZ00121
      Location:99 → 248
      PTZ00121; MAEBL; Provisional

    6. XM_022403946.2 → XP_022259654.1  SH2 domain-containing protein 4A isoform X3

      Conserved Domains (1) summary
      PTZ00121
      Location:99 → 248
      PTZ00121; MAEBL; Provisional
    Nucleotide Protein
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