U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    HDAC2 histone deacetylase 2 [ Canis lupus familiaris (dog) ]

    Gene ID: 475035, updated on 17-Aug-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    HDAC2provided by VGNC
    Official Full Name
    histone deacetylase 2provided by VGNC
    Primary source
    VGNC:VGNC:49101
    See related
    Ensembl:ENSCAFG00845020776
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See HDAC2 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 12 NC_051816.1 (70933049..70962557, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 12 NC_006594.4 (69799259..69828714, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 12 NC_049233.1 (70454633..70484021, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 12 NC_049272.1 (70285352..70314769, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 12 NC_049753.1 (70123758..70153135, complement)

    Chromosome 12 - NC_051816.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106559557 Neighboring gene myristoylated alanine rich protein kinase C substrate Neighboring gene heparan sulfate-glucosamine 3-sulfotransferase 5 Neighboring gene uncharacterized LOC111098407 Neighboring gene uncharacterized LOC111098196

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Comparative radiation hybrid map of canine chromosome 1 incorporating SNP and indel polymorphisms. Housley DJ, et al. Genomics, 2004 Aug. PMID 15233990
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables histone deacetylase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    histone deacetylase 2
    XP_013973700.2
    XP_038348608.1
    XP_038348609.1
    XP_038348610.1
    XP_038410927.1
    XP_038410928.1
    XP_038410929.1
    XP_038474797.1
    XP_038474798.1
    XP_038474799.1
    XP_038534730.1
    XP_038534734.1
    XP_038540351.1
    XP_038540352.1
    XP_038540353.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051816.1 Reference ROS_Cfam_1.0

      Range
      70933049..70962557 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038684423.1 → XP_038540351.1  histone deacetylase 2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0MAX5
      Conserved Domains (2) summary
      COG4547
      Location:407 → 500
      CobT2; Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphorib... [Coenzyme transport and metabolism]
      cl17011
      Location:39 → 395
      Arginase_HDAC; Arginase-like and histone-like hydrolases

    2. XM_038684424.1 → XP_038540352.1  histone deacetylase 2 isoform X2

      UniProtKB/TrEMBL
      A0A8C0MAX5, A0A8C0MG29, A0A8I3S1X7
      Related
      ENSCAFP00845028668.1, ENSCAFT00845036630.1
      Conserved Domains (2) summary
      cd10011
      Location:9 → 374
      HDAC2; Histone deacetylase 2 (HDAC2)
      COG4547
      Location:386 → 479
      CobT2; Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphorib... [Coenzyme transport and metabolism]

    3. XM_038684425.1 → XP_038540353.1  histone deacetylase 2 isoform X3

      UniProtKB/TrEMBL
      A0A8C0MAX5
      Conserved Domains (2) summary
      COG4547
      Location:356 → 449
      CobT2; Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphorib... [Coenzyme transport and metabolism]
      cl17011
      Location:1 → 344
      Arginase_HDAC; Arginase-like and histone-like hydrolases

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049272.1 Alternate UMICH_Zoey_3.1

      Range
      70285352..70314769 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038492680.1 → XP_038348608.1  histone deacetylase 2 isoform X1

    2. XM_038492681.1 → XP_038348609.1  histone deacetylase 2 isoform X2

      Conserved Domains (2) summary
      cd10011
      Location:9 → 374
      HDAC2; Histone deacetylase 2 (HDAC2)
      COG4547
      Location:386 → 479
      CobT2; Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphorib... [Coenzyme transport and metabolism]

    3. XM_038492682.1 → XP_038348610.1  histone deacetylase 2 isoform X3

      Conserved Domains (2) summary
      COG4547
      Location:356 → 449
      CobT2; Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphorib... [Coenzyme transport and metabolism]
      cl17011
      Location:1 → 344
      Arginase_HDAC; Arginase-like and histone-like hydrolases

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049753.1 Alternate UNSW_CanFamBas_1.0

      Range
      70123758..70153135 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038618869.1 → XP_038474797.1  histone deacetylase 2 isoform X1

      Conserved Domains (2) summary
      COG4547
      Location:407 → 500
      CobT2; Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphorib... [Coenzyme transport and metabolism]
      cl17011
      Location:39 → 395
      Arginase_HDAC; Arginase-like and histone-like hydrolases

    2. XM_038618870.1 → XP_038474798.1  histone deacetylase 2 isoform X2

      Conserved Domains (2) summary
      cd10011
      Location:9 → 374
      HDAC2; Histone deacetylase 2 (HDAC2)
      COG4547
      Location:386 → 479
      CobT2; Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphorib... [Coenzyme transport and metabolism]

    3. XM_038618871.1 → XP_038474799.1  histone deacetylase 2 isoform X3

      Conserved Domains (2) summary
      COG4547
      Location:356 → 449
      CobT2; Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphorib... [Coenzyme transport and metabolism]
      cl17011
      Location:1 → 344
      Arginase_HDAC; Arginase-like and histone-like hydrolases

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049233.1 Alternate UU_Cfam_GSD_1.0

      Range
      70454633..70484021 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038554999.1 → XP_038410927.1  histone deacetylase 2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0MAX5

    2. XM_038555000.1 → XP_038410928.1  histone deacetylase 2 isoform X2

      UniProtKB/TrEMBL
      A0A8C0MAX5, A0A8C0MG29, A0A8I3S1X7
      Conserved Domains (2) summary
      cd10011
      Location:9 → 374
      HDAC2; Histone deacetylase 2 (HDAC2)
      COG4547
      Location:386 → 479
      CobT2; Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphorib... [Coenzyme transport and metabolism]

    3. XM_038555001.1 → XP_038410929.1  histone deacetylase 2 isoform X3

      UniProtKB/TrEMBL
      A0A8C0MAX5
      Conserved Domains (2) summary
      COG4547
      Location:356 → 449
      CobT2; Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphorib... [Coenzyme transport and metabolism]
      cl17011
      Location:1 → 344
      Arginase_HDAC; Arginase-like and histone-like hydrolases

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006594.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      69799259..69828714 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_014118225.3 → XP_013973700.2  histone deacetylase 2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0MAX5
      Conserved Domains (2) summary
      pfam14797
      Location:414 → 508
      SEEEED; Serine-rich region of AP3B1, clathrin-adaptor complex
      cl17011
      Location:39 → 395
      Arginase_HDAC; Arginase-like and histone-like hydrolases

    2. XM_038678802.1 → XP_038534730.1  histone deacetylase 2 isoform X2

      UniProtKB/TrEMBL
      A0A8C0MAX5, A0A8C0MG29, A0A8I3S1X7
      Conserved Domains (2) summary
      cd10011
      Location:9 → 374
      HDAC2; Histone deacetylase 2 (HDAC2)
      COG4547
      Location:386 → 479
      CobT2; Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphorib... [Coenzyme transport and metabolism]

    3. XM_038678806.1 → XP_038534734.1  histone deacetylase 2 isoform X3

      UniProtKB/TrEMBL
      A0A8C0MAX5
      Conserved Domains (2) summary
      COG4547
      Location:356 → 449
      CobT2; Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphorib... [Coenzyme transport and metabolism]
      cl17011
      Location:1 → 344
      Arginase_HDAC; Arginase-like and histone-like hydrolases
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials