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    ACO2 aconitase 2 [ Canis lupus familiaris (dog) ]

    Gene ID: 474487, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ACO2provided by VGNC
    Official Full Name
    aconitase 2provided by VGNC
    Primary source
    VGNC:VGNC:37514
    See related
    Ensembl:ENSCAFG00845016969
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See ACO2 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 10 NC_051814.1 (24487132..24543453, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 10 NC_006592.4 (23674973..23731276, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 10 NC_049231.1 (24699242..24755563, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 10 NC_049270.1 (24203926..24260231, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 10 NC_049751.1 (24525094..24581120, complement)

    Chromosome 10 - NC_051814.1Genomic Context describing neighboring genes Neighboring gene phosphomannomutase 1 Neighboring gene cold shock domain containing C2 Neighboring gene RNA polymerase III subunit H Neighboring gene uncharacterized LOC111097641 Neighboring gene uncharacterized LOC119873622 Neighboring gene PHD finger protein 5A Neighboring gene transducer of ERBB2, 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Light-activated BioID - an optically activated proximity labeling system to study protein-protein interactions. Shafraz O, et al. J Cell Sci, 2023 Oct 1. PMID 37756605, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 4 iron, 4 sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables aconitate hydratase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in tricarboxylic acid cycle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    aconitate hydratase, mitochondrial
    XP_038344424.1
    XP_038406351.1
    XP_038470316.1
    XP_038535659.1
    XP_849166.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051814.1 Reference ROS_Cfam_1.0

      Range
      24487132..24543453 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038679731.1 → XP_038535659.1  aconitate hydratase, mitochondrial

      UniProtKB/TrEMBL
      A0A8C0JKD3, A0A8C0P9S0, A0A8I3P6L6, A0A8P0S723
      Related
      ENSCAFP00845023587.1, ENSCAFT00845030069.1
      Conserved Domains (1) summary
      TIGR01340
      Location:45 → 775
      aconitase_mito; aconitate hydratase, mitochondrial

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049270.1 Alternate UMICH_Zoey_3.1

      Range
      24203926..24260231 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038488496.1 → XP_038344424.1  aconitate hydratase, mitochondrial

      Conserved Domains (1) summary
      TIGR01340
      Location:45 → 775
      aconitase_mito; aconitate hydratase, mitochondrial

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049751.1 Alternate UNSW_CanFamBas_1.0

      Range
      24525094..24581120 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038614388.1 → XP_038470316.1  aconitate hydratase, mitochondrial

      Conserved Domains (1) summary
      TIGR01340
      Location:45 → 775
      aconitase_mito; aconitate hydratase, mitochondrial

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049231.1 Alternate UU_Cfam_GSD_1.0

      Range
      24699242..24755563 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038550423.1 → XP_038406351.1  aconitate hydratase, mitochondrial

      UniProtKB/TrEMBL
      A0A8C0JKD3, A0A8C0P9S0, A0A8I3P6L6, A0A8P0S723
      Conserved Domains (1) summary
      TIGR01340
      Location:45 → 775
      aconitase_mito; aconitate hydratase, mitochondrial

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006592.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      23674973..23731276 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_844073.6 → XP_849166.1  aconitate hydratase, mitochondrial

      UniProtKB/TrEMBL
      A0A8C0JKD3, A0A8C0P9S0, A0A8I3P6L6, A0A8P0S723
      Conserved Domains (1) summary
      TIGR01340
      Location:45 → 775
      aconitase_mito; aconitate hydratase, mitochondrial
    Nucleotide Protein
    Heading Accession and Version

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