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    SMOC2 SPARC related modular calcium binding 2 [ Pan troglodytes (chimpanzee) ]

    Gene ID: 463137, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SMOC2provided by VGNC
    Official Full Name
    SPARC related modular calcium binding 2provided by VGNC
    Primary source
    VGNC:VGNC:3704
    Locus tag
    CK820_G0038920
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Orthologs
    human mouse all
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    Genomic context

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    See SMOC2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 5 NC_072403.2 (180522011..180747162)
    RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 6 NC_072404.1 (180520525..180745655)

    Chromosome 5 - NC_072403.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107975406 Neighboring gene dishevelled binding antagonist of beta catenin 2 Neighboring gene uncharacterized LOC107975407 Neighboring gene uncharacterized LOC107975410 Neighboring gene uncharacterized LOC129144351

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables extracellular matrix binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables heparin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in extracellular matrix organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in basement membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    SPARC-related modular calcium-binding protein 2
    Names
    secreted modular calcium-binding protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Genomic

    1. NC_072403.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

      Range
      180522011..180747162
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024357524.3 → XP_024213292.1  SPARC-related modular calcium-binding protein 2 isoform X4

      UniProtKB/TrEMBL
      A0A2J8KHH5, A0A803KJK9, H2QU20, K7BUA7
      Conserved Domains (5) summary
      smart00280
      Location:39 → 84
      KAZAL; Kazal type serine protease inhibitors
      cd00191
      Location:215 → 281
      TY; Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases
      cd16241
      Location:304 → 417
      EFh_SPARC_SMOC2; EF-hand, extracellular calcium-binding (EC) motif, found in secreted modular calcium-binding protein 2 (SMOC-2)
      pfam00086
      Location:90 → 153
      Thyroglobulin_1; Thyroglobulin type-1 repeat
      pfam16597
      Location:154 → 214
      Thyroglob_assoc; Thyroglobulin_1 repeat associated disordered domain

    2. XM_024357523.3 → XP_024213291.1  SPARC-related modular calcium-binding protein 2 isoform X3

      UniProtKB/TrEMBL
      A0A2J8KHH8, H2QU20
      Conserved Domains (5) summary
      smart00280
      Location:39 → 84
      KAZAL; Kazal type serine protease inhibitors
      cd00191
      Location:226 → 292
      TY; Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases
      pfam00086
      Location:90 → 153
      Thyroglobulin_1; Thyroglobulin type-1 repeat
      pfam16597
      Location:154 → 223
      Thyroglob_assoc; Thyroglobulin_1 repeat associated disordered domain
      cd16241
      Location:315 → 428
      EFh_SPARC_SMOC2; EF-hand, extracellular calcium-binding (EC) motif, found in secreted modular calcium-binding protein 2 (SMOC-2)

    3. XM_016956668.4 → XP_016812157.2  SPARC-related modular calcium-binding protein 2 isoform X2

      Conserved Domains (5) summary
      smart00280
      Location:39 → 84
      KAZAL; Kazal type serine protease inhibitors
      cd00191
      Location:215 → 281
      TY; Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases
      pfam00086
      Location:90 → 153
      Thyroglobulin_1; Thyroglobulin type-1 repeat
      pfam16597
      Location:154 → 212
      Thyroglob_assoc; Thyroglobulin_1 repeat associated disordered domain
      cd16241
      Location:304 → 417
      EFh_SPARC_SMOC2; EF-hand, extracellular calcium-binding (EC) motif, found in secreted modular calcium-binding protein 2 (SMOC-2)

    4. XM_024357522.3 → XP_024213290.1  SPARC-related modular calcium-binding protein 2 isoform X1

      Conserved Domains (5) summary
      smart00280
      Location:39 → 84
      KAZAL; Kazal type serine protease inhibitors
      cd00191
      Location:226 → 292
      TY; Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases
      pfam00086
      Location:90 → 153
      Thyroglobulin_1; Thyroglobulin type-1 repeat
      pfam16597
      Location:154 → 223
      Thyroglob_assoc; Thyroglobulin_1 repeat associated disordered domain
      cd16241
      Location:315 → 428
      EFh_SPARC_SMOC2; EF-hand, extracellular calcium-binding (EC) motif, found in secreted modular calcium-binding protein 2 (SMOC-2)
    Nucleotide Protein
    Heading Accession and Version

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