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    MARCHF7 membrane associated ring-CH-type finger 7 [ Pan troglodytes (chimpanzee) ]

    Gene ID: 459681, updated on 17-Aug-2024

    Summary

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    Official Symbol
    MARCHF7provided by VGNC
    Official Full Name
    membrane associated ring-CH-type finger 7provided by VGNC
    Primary source
    VGNC:VGNC:2009
    Locus tag
    CK820_G0001334
    See related
    Ensembl:ENSPTRG00000012564
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Also known as
    MARCH7
    Orthologs
    human mouse all
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    Genomic context

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    See MARCHF7 in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 13 NC_072411.2 (61762274..61818122)
    RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 2B NC_072400.1 (61762126..61818111)

    Chromosome 13 - NC_072411.2Genomic Context describing neighboring genes Neighboring gene bromodomain adjacent to zinc finger domain 2B Neighboring gene CAPZA1 pseudogene 2 Neighboring gene small ribosomal subunit protein eS1-like Neighboring gene CD302 molecule Neighboring gene lymphocyte antigen 75

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Major chimpanzee-specific structural changes in sperm development-associated genes. Kim RN, et al. Funct Integr Genomics, 2011 Sep. PMID 21484476
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ubiquitin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin conjugating enzyme binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein autoubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase MARCHF7
    Names
    axotrophin
    membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase
    NP_001267249.1
    XP_009441740.1
    XP_009441741.1
    XP_009441743.1
    XP_009441744.1
    XP_009441745.1
    XP_009441749.1
    XP_009441750.1
    XP_009441752.1
    XP_016804817.1
    XP_054534733.1
    XP_054534736.1
    XP_054534738.1
    XP_054534743.1
    XP_054534752.1
    XP_054534753.1
    XP_054534755.1
    XP_054534760.1
    XP_054534761.1
    XP_054534762.1
    XP_054534764.1
    XP_054534765.1
    XP_054534766.1
    XP_063646290.1
    XP_063646291.1
    XP_063646292.1
    XP_063646293.1
    XP_063646294.1
    XP_063646295.1
    XP_063646296.1
    XP_063646297.1
    XP_063646298.1
    XP_063646299.1
    XP_063646300.1
    XP_063646301.1
    XP_063646302.1
    XP_063646303.1
    XP_063646304.1
    XP_063646305.1
    XP_063646306.1
    XP_063646307.1
    XP_063646308.1
    XP_063646309.1
    XP_063646310.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001280320.1 → NP_001267249.1  E3 ubiquitin-protein ligase MARCHF7

      See identical proteins and their annotated locations for NP_001267249.1

      Status: PROVISIONAL

      Source sequence(s)
      AK306407
      UniProtKB/TrEMBL
      G2HI43
      Conserved Domains (1) summary
      smart00744
      Location:552 → 608
      RINGv; The RING-variant domain is a C4HC3 zinc-finger like motif found in a number of cellular and viral proteins

    RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Genomic

    1. NC_072411.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

      Range
      61762274..61818122
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009443470.5 → XP_009441745.1  E3 ubiquitin-protein ligase MARCHF7 isoform X1

      See identical proteins and their annotated locations for XP_009441745.1

      UniProtKB/TrEMBL
      A0A2J8PPZ3, A0A803KI46, K7CA02
      Conserved Domains (1) summary
      cd16812
      Location:552 → 610
      RING_CH-C4HC3_MARCH7; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING-CH7 (MARCH7)

    2. XM_009443465.5 → XP_009441740.1  E3 ubiquitin-protein ligase MARCHF7 isoform X1

      See identical proteins and their annotated locations for XP_009441740.1

      UniProtKB/TrEMBL
      A0A2J8PPZ3, A0A803KI46, K7CA02
      Conserved Domains (1) summary
      cd16812
      Location:552 → 610
      RING_CH-C4HC3_MARCH7; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING-CH7 (MARCH7)

    3. XM_054678768.2 → XP_054534743.1  E3 ubiquitin-protein ligase MARCHF7 isoform X1

      UniProtKB/TrEMBL
      A0A2J8PPZ3, A0A803KI46, K7CA02

    4. XM_009443466.5 → XP_009441741.1  E3 ubiquitin-protein ligase MARCHF7 isoform X1

      See identical proteins and their annotated locations for XP_009441741.1

      UniProtKB/TrEMBL
      A0A2J8PPZ3, A0A803KI46, K7CA02
      Conserved Domains (1) summary
      cd16812
      Location:552 → 610
      RING_CH-C4HC3_MARCH7; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING-CH7 (MARCH7)

    5. XM_054678758.2 → XP_054534733.1  E3 ubiquitin-protein ligase MARCHF7 isoform X1

      UniProtKB/TrEMBL
      A0A2J8PPZ3, A0A803KI46, K7CA02

    6. XM_054678791.2 → XP_054534766.1  E3 ubiquitin-protein ligase MARCHF7 isoform X6

    7. XM_054678789.2 → XP_054534764.1  E3 ubiquitin-protein ligase MARCHF7 isoform X6

    8. XM_009443469.5 → XP_009441744.1  E3 ubiquitin-protein ligase MARCHF7 isoform X1

      See identical proteins and their annotated locations for XP_009441744.1

      UniProtKB/TrEMBL
      A0A2J8PPZ3, A0A803KI46, K7CA02
      Conserved Domains (1) summary
      cd16812
      Location:552 → 610
      RING_CH-C4HC3_MARCH7; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING-CH7 (MARCH7)

    9. XM_054678780.2 → XP_054534755.1  E3 ubiquitin-protein ligase MARCHF7 isoform X1

      UniProtKB/TrEMBL
      A0A2J8PPZ3, A0A803KI46, K7CA02

    10. XM_054678786.2 → XP_054534761.1  E3 ubiquitin-protein ligase MARCHF7 isoform X2

    11. XM_009443468.5 → XP_009441743.1  E3 ubiquitin-protein ligase MARCHF7 isoform X1

      See identical proteins and their annotated locations for XP_009441743.1

      UniProtKB/TrEMBL
      A0A2J8PPZ3, A0A803KI46, K7CA02
      Conserved Domains (1) summary
      cd16812
      Location:552 → 610
      RING_CH-C4HC3_MARCH7; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING-CH7 (MARCH7)

    12. XM_054678763.2 → XP_054534738.1  E3 ubiquitin-protein ligase MARCHF7 isoform X1

      UniProtKB/TrEMBL
      A0A2J8PPZ3, A0A803KI46, K7CA02

    13. XM_054678761.2 → XP_054534736.1  E3 ubiquitin-protein ligase MARCHF7 isoform X1

      UniProtKB/TrEMBL
      A0A2J8PPZ3, A0A803KI46, K7CA02

    14. XM_054678785.2 → XP_054534760.1  E3 ubiquitin-protein ligase MARCHF7 isoform X2

    15. XM_054678787.2 → XP_054534762.1  E3 ubiquitin-protein ligase MARCHF7 isoform X2

    16. XM_063790235.1 → XP_063646305.1  E3 ubiquitin-protein ligase MARCHF7 isoform X6

    17. XM_009443475.5 → XP_009441750.1  E3 ubiquitin-protein ligase MARCHF7 isoform X4

      See identical proteins and their annotated locations for XP_009441750.1

      Conserved Domains (1) summary
      smart00744
      Location:496 → 552
      RINGv; The RING-variant domain is a C4HC3 zinc-finger like motif found in a number of cellular and viral proteins

    18. XM_009443477.5 → XP_009441752.1  E3 ubiquitin-protein ligase MARCHF7 isoform X5

      See identical proteins and their annotated locations for XP_009441752.1

      UniProtKB/TrEMBL
      A0A2J8PPZ1, A0A5S6R916, H2QIV6
      Related
      ENSPTRP00000021479.3
      Conserved Domains (1) summary
      cl17238
      Location:496 → 554
      RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

    19. XM_054678778.2 → XP_054534753.1  E3 ubiquitin-protein ligase MARCHF7 isoform X1

      UniProtKB/TrEMBL
      A0A2J8PPZ3, A0A803KI46, K7CA02

    20. XM_054678777.2 → XP_054534752.1  E3 ubiquitin-protein ligase MARCHF7 isoform X1

      UniProtKB/TrEMBL
      A0A2J8PPZ3, A0A803KI46, K7CA02

    21. XM_063790220.1 → XP_063646290.1  E3 ubiquitin-protein ligase MARCHF7 isoform X1

      UniProtKB/TrEMBL
      A0A2J8PPZ3, A0A803KI46, K7CA02

    22. XM_063790229.1 → XP_063646299.1  E3 ubiquitin-protein ligase MARCHF7 isoform X4

    23. XM_063790224.1 → XP_063646294.1  E3 ubiquitin-protein ligase MARCHF7 isoform X2

    24. XM_063790223.1 → XP_063646293.1  E3 ubiquitin-protein ligase MARCHF7 isoform X2

    25. XM_063790234.1 → XP_063646304.1  E3 ubiquitin-protein ligase MARCHF7 isoform X5

      UniProtKB/TrEMBL
      A0A2J8PPZ1, A0A5S6R916, H2QIV6

    26. XM_063790222.1 → XP_063646292.1  E3 ubiquitin-protein ligase MARCHF7 isoform X2

    27. XM_063790228.1 → XP_063646298.1  E3 ubiquitin-protein ligase MARCHF7 isoform X4

    28. XM_063790221.1 → XP_063646291.1  E3 ubiquitin-protein ligase MARCHF7 isoform X2

    29. XM_063790226.1 → XP_063646296.1  E3 ubiquitin-protein ligase MARCHF7 isoform X4

    30. XM_063790230.1 → XP_063646300.1  E3 ubiquitin-protein ligase MARCHF7 isoform X4

    31. XM_063790236.1 → XP_063646306.1  E3 ubiquitin-protein ligase MARCHF7 isoform X7

    32. XM_063790239.1 → XP_063646309.1  E3 ubiquitin-protein ligase MARCHF7 isoform X8

    33. XM_063790237.1 → XP_063646307.1  E3 ubiquitin-protein ligase MARCHF7 isoform X7

    34. XM_063790225.1 → XP_063646295.1  E3 ubiquitin-protein ligase MARCHF7 isoform X4

    35. XM_063790233.1 → XP_063646303.1  E3 ubiquitin-protein ligase MARCHF7 isoform X5

      UniProtKB/TrEMBL
      A0A2J8PPZ1, A0A5S6R916, H2QIV6

    36. XM_054678790.2 → XP_054534765.1  E3 ubiquitin-protein ligase MARCHF7 isoform X7

    37. XM_063790231.1 → XP_063646301.1  E3 ubiquitin-protein ligase MARCHF7 isoform X4

    38. XM_063790240.1 → XP_063646310.1  E3 ubiquitin-protein ligase MARCHF7 isoform X8

    39. XM_009443474.4 → XP_009441749.1  E3 ubiquitin-protein ligase MARCHF7 isoform X4

      See identical proteins and their annotated locations for XP_009441749.1

      Conserved Domains (1) summary
      smart00744
      Location:496 → 552
      RINGv; The RING-variant domain is a C4HC3 zinc-finger like motif found in a number of cellular and viral proteins

    40. XM_063790232.1 → XP_063646302.1  E3 ubiquitin-protein ligase MARCHF7 isoform X5

      UniProtKB/TrEMBL
      A0A2J8PPZ1, A0A5S6R916, H2QIV6

    41. XM_063790238.1 → XP_063646308.1  E3 ubiquitin-protein ligase MARCHF7 isoform X8

    42. XM_063790227.1 → XP_063646297.1  E3 ubiquitin-protein ligase MARCHF7 isoform X4

    43. XM_016949328.4 → XP_016804817.1  E3 ubiquitin-protein ligase MARCHF7 isoform X3

      UniProtKB/TrEMBL
      A0A2I3RJZ0, A0A2J8PQ02, A0A5S6R969
      Related
      ENSPTRP00000064978.1
      Conserved Domains (1) summary
      cd16812
      Location:514 → 572
      RING_CH-C4HC3_MARCH7; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING-CH7 (MARCH7)

    RNA

    1. XR_010149656.1 RNA Sequence

    2. XR_010149658.1 RNA Sequence

    3. XR_010149655.1 RNA Sequence

    4. XR_010149657.1 RNA Sequence

    5. XR_008546518.1 RNA Sequence

    6. XR_010149659.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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