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    DCAF8 DDB1 and CUL4 associated factor 8 [ Pan troglodytes (chimpanzee) ]

    Gene ID: 457434, updated on 6-Jun-2024

    Summary

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    Official Symbol
    DCAF8provided by VGNC
    Official Full Name
    DDB1 and CUL4 associated factor 8provided by VGNC
    Primary source
    VGNC:VGNC:99658
    Locus tag
    CK820_G0049299
    See related
    Ensembl:ENSPTRG00000001546
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Also known as
    WDR42A
    Orthologs
    human mouse all
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    Genomic context

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    See DCAF8 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 1 NC_072398.2 (88938702..88986428)
    RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 1 NC_072398.1 (142363304..142410143, complement)

    Chromosome 1 - NC_072398.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107968979 Neighboring gene peroxisomal biogenesis factor 19 Neighboring gene uncharacterized LOC107968973 Neighboring gene small ribosomal subunit protein uS2-like Neighboring gene proliferation and apoptosis adaptor protein 15 Neighboring gene uncharacterized LOC134810176 Neighboring gene uncharacterized LOC134810179

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Cul4-RING E3 ubiquitin ligase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DDB1- and CUL4-associated factor 8
    Names
    H326
    WD repeat domain 42A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Genomic

    1. NC_072398.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

      Range
      88938702..88986428
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063812057.1 → XP_063668127.1  DDB1- and CUL4-associated factor 8 isoform X1

      UniProtKB/TrEMBL
      K7BCQ6

    2. XM_009435588.3 → XP_009433863.1  DDB1- and CUL4-associated factor 8 isoform X2

      See identical proteins and their annotated locations for XP_009433863.1

      UniProtKB/TrEMBL
      A0A2J8JAE3, A0A6D2W2J2, H2Q0E2, K7BCQ6
      Related
      ENSPTRP00000082654.1
      Conserved Domains (2) summary
      sd00039
      Location:198 → 234
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:189 → 506
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    3. XM_009435620.3 → XP_009433895.1  DDB1- and CUL4-associated factor 8 isoform X3

      See identical proteins and their annotated locations for XP_009433895.1

      UniProtKB/TrEMBL
      K7BCQ6
      Conserved Domains (2) summary
      sd00039
      Location:173 → 209
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:164 → 481
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    4. XM_513922.8 → XP_513922.3  DDB1- and CUL4-associated factor 8 isoform X2

      See identical proteins and their annotated locations for XP_513922.3

      UniProtKB/TrEMBL
      A0A2J8JAE3, A0A6D2W2J2, H2Q0E2, K7BCQ6
      Conserved Domains (2) summary
      sd00039
      Location:198 → 234
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:189 → 506
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    5. XM_003308543.6 → XP_003308591.1  DDB1- and CUL4-associated factor 8 isoform X2

      See identical proteins and their annotated locations for XP_003308591.1

      UniProtKB/TrEMBL
      A0A2J8JAE3, A0A6D2W2J2, H2Q0E2, K7BCQ6
      Related
      ENSPTRP00000002595.2
      Conserved Domains (2) summary
      sd00039
      Location:198 → 234
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:189 → 506
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    6. XM_003308544.6 → XP_003308592.1  DDB1- and CUL4-associated factor 8 isoform X2

      See identical proteins and their annotated locations for XP_003308592.1

      UniProtKB/TrEMBL
      A0A2J8JAE3, A0A6D2W2J2, H2Q0E2, K7BCQ6
      Conserved Domains (2) summary
      sd00039
      Location:198 → 234
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:189 → 506
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    7. XM_009435601.5 → XP_009433876.1  DDB1- and CUL4-associated factor 8 isoform X2

      See identical proteins and their annotated locations for XP_009433876.1

      UniProtKB/TrEMBL
      A0A2J8JAE3, A0A6D2W2J2, H2Q0E2, K7BCQ6
      Conserved Domains (2) summary
      sd00039
      Location:198 → 234
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:189 → 506
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    8. XM_009435606.5 → XP_009433881.1  DDB1- and CUL4-associated factor 8 isoform X3

      See identical proteins and their annotated locations for XP_009433881.1

      UniProtKB/TrEMBL
      K7BCQ6
      Conserved Domains (2) summary
      sd00039
      Location:173 → 209
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:164 → 481
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    9. XM_063812074.1 → XP_063668144.1  DDB1- and CUL4-associated factor 8 isoform X3

      UniProtKB/TrEMBL
      K7BCQ6

    10. XM_009435575.5 → XP_009433850.1  DDB1- and CUL4-associated factor 8 isoform X2

      See identical proteins and their annotated locations for XP_009433850.1

      UniProtKB/TrEMBL
      A0A2J8JAE3, A0A6D2W2J2, H2Q0E2, K7BCQ6
      Conserved Domains (2) summary
      sd00039
      Location:198 → 234
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:189 → 506
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    11. XM_009435568.5 → XP_009433843.1  DDB1- and CUL4-associated factor 8 isoform X2

      See identical proteins and their annotated locations for XP_009433843.1

      UniProtKB/TrEMBL
      A0A2J8JAE3, A0A6D2W2J2, H2Q0E2, K7BCQ6
      Conserved Domains (2) summary
      sd00039
      Location:198 → 234
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:189 → 506
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    12. XM_063812060.1 → XP_063668130.1  DDB1- and CUL4-associated factor 8 isoform X2

      UniProtKB/TrEMBL
      A0A2J8JAE3, A0A6D2W2J2, H2Q0E2, K7BCQ6

    13. XM_063812064.1 → XP_063668134.1  DDB1- and CUL4-associated factor 8 isoform X2

      UniProtKB/TrEMBL
      A0A2J8JAE3, A0A6D2W2J2, H2Q0E2, K7BCQ6

    14. XM_009435611.5 → XP_009433886.1  DDB1- and CUL4-associated factor 8 isoform X3

      See identical proteins and their annotated locations for XP_009433886.1

      UniProtKB/TrEMBL
      K7BCQ6
      Conserved Domains (2) summary
      sd00039
      Location:173 → 209
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:164 → 481
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    15. XM_016930354.4 → XP_016785843.1  DDB1- and CUL4-associated factor 8 isoform X2

      UniProtKB/TrEMBL
      A0A2J8JAE3, A0A6D2W2J2, H2Q0E2, K7BCQ6
      Conserved Domains (2) summary
      sd00039
      Location:198 → 234
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:189 → 506
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    16. XM_063812059.1 → XP_063668129.1  DDB1- and CUL4-associated factor 8 isoform X2

      UniProtKB/TrEMBL
      A0A2J8JAE3, A0A6D2W2J2, H2Q0E2, K7BCQ6

    RNA

    1. XR_010157539.1 RNA Sequence

    2. XR_001710537.3 RNA Sequence

    3. XR_010157576.1 RNA Sequence

    4. XR_010157577.1 RNA Sequence

    5. XR_010157556.1 RNA Sequence

    6. XR_010157563.1 RNA Sequence

    7. XR_010157565.1 RNA Sequence

    8. XR_010157572.1 RNA Sequence

    9. XR_010157575.1 RNA Sequence

    10. XR_010157548.1 RNA Sequence

    11. XR_010157558.1 RNA Sequence

    12. XR_010157559.1 RNA Sequence

    13. XR_010157545.1 RNA Sequence

    14. XR_010157549.1 RNA Sequence

    15. XR_010157550.1 RNA Sequence

    16. XR_010157555.1 RNA Sequence

    17. XR_010157562.1 RNA Sequence

    18. XR_010157560.1 RNA Sequence

    19. XR_010157569.1 RNA Sequence

    20. XR_010157546.1 RNA Sequence

    21. XR_010157557.1 RNA Sequence

    22. XR_010157571.1 RNA Sequence

    23. XR_010157553.1 RNA Sequence

    24. XR_010157573.1 RNA Sequence

    25. XR_010157574.1 RNA Sequence

    Nucleotide Protein
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