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    DAGLA diacylglycerol lipase alpha [ Pan troglodytes (chimpanzee) ]

    Gene ID: 451241, updated on 18-Sep-2024

    Summary

    Official Symbol
    DAGLAprovided by VGNC
    Official Full Name
    diacylglycerol lipase alphaprovided by VGNC
    Primary source
    VGNC:VGNC:11335
    Locus tag
    CK820_G0030913
    See related
    Ensembl:ENSPTRG00000003747
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Orthologs
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    Genomic context

    See DAGLA in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 9 NC_072407.2 (63930400..63997428)
    RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 11 NC_072409.1 (63039761..63106789)

    Chromosome 9 - NC_072407.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134807354 Neighboring gene large ribosomal subunit protein uL10-like Neighboring gene myelin regulatory factor Neighboring gene transmembrane protein 258 Neighboring gene flap structure-specific endonuclease 1

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables lipoprotein lipase activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in arachidonate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in diacylglycerol catabolic process IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in retrograde trans-synaptic signaling by endocannabinoid IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in dendrite membrane IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in postsynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    sn1-specific diacylglycerol lipase alpha; diacylglycerol lipase-alpha
    Names
    neural stem cell-derived dendrite regulator
    XP_016776509.1
    XP_063639027.1
    XP_063639028.1
    XP_063639029.1
    XP_063639030.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Genomic

    1. NC_072407.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

      Range
      63930400..63997428
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_016921020.4XP_016776509.1  diacylglycerol lipase-alpha isoform X1

      UniProtKB/TrEMBL
      A0A2J8LD89, A0A6D2XSB7, H2Q3U4, K6ZXB4
      Related
      ENSPTRP00000006442.4
      Conserved Domains (1) summary
      cd00519
      Location:288529
      Lipase_3; Lipase (class 3). Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation," the process of ...
    2. XM_063782959.1XP_063639029.1  diacylglycerol lipase-alpha isoform X2

    3. XM_063782958.1XP_063639028.1  diacylglycerol lipase-alpha isoform X1

      UniProtKB/TrEMBL
      A0A2J8LD89, A0A6D2XSB7, H2Q3U4, K6ZXB4
    4. XM_063782957.1XP_063639027.1  diacylglycerol lipase-alpha isoform X1

      UniProtKB/TrEMBL
      A0A2J8LD89, A0A6D2XSB7, H2Q3U4, K6ZXB4
    5. XM_063782960.1XP_063639030.1  diacylglycerol lipase-alpha isoform X3