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    F8 coagulation factor VIII [ Gallus gallus (chicken) ]

    Gene ID: 422199, updated on 17-Aug-2024

    Summary

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    Symbol
    F8provided by CGNC
    Full Name
    coagulation factor VIIIprovided by CGNC
    Primary source
    CGNC:51654
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 4
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 4 NC_052535.1 (2101058..2120537, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 4 NC_052576.1 (2137552..2156961, complement)

    Chromosome 4 - NC_052535.1Genomic Context describing neighboring genes Neighboring gene membrane palmitoylated protein 1 Neighboring gene small integral membrane protein 9 Neighboring gene microRNA 222b Neighboring gene FUN14 domain containing 2 Neighboring gene C-X9-C motif containing 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables copper ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    coagulation factor VIII
    Names
    coagulation factor VIII, procoagulant component (hemophilia A)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052535.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      2101058..2120537 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_420193.8 → XP_420193.5  coagulation factor VIII

      UniProtKB/TrEMBL
      A0A1D5NW08
      Conserved Domains (5) summary
      smart00231
      Location:1797 → 1946
      FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain
      cd00057
      Location:1800 → 1945
      FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
      cd04228
      Location:1474 → 1638
      CuRO_5_FVIII_like; The fifth cupredoxin domain of coagulation factor VIII and similar proteins
      cd11018
      Location:1650 → 1793
      CuRO_6_FVIII_like; The sixth cupredoxin domain of coagulation factor VIII and similar proteins
      cl19115
      Location:426 → 602
      Cupredoxin; Cupredoxin superfamily

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052576.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      2137552..2156961 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040669502.2 → XP_040525436.1  coagulation factor VIII

      Conserved Domains (4) summary
      cd00057
      Location:1800 → 1945
      FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
      cd04228
      Location:1474 → 1638
      CuRO_5_FVIII_like; The fifth cupredoxin domain of coagulation factor VIII and similar proteins
      cd11018
      Location:1650 → 1793
      CuRO_6_FVIII_like; The sixth cupredoxin domain of coagulation factor VIII and similar proteins
      cl19115
      Location:426 → 602
      Cupredoxin; Cupredoxin superfamily
    Nucleotide Protein
    Heading Accession and Version

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