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    CAPN13 calpain 13 [ Gallus gallus (chicken) ]

    Gene ID: 421304, updated on 17-Aug-2024

    Summary

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    Official Symbol
    CAPN13provided by CGNC
    Official Full Name
    calpain 13provided by CGNC
    Primary source
    CGNC:14087
    See related
    Ensembl:ENSGALG00010017447
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    calpain-13
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    Genomic context

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    See CAPN13 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 3 NC_052534.1 (8050658..8085858)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 3 NC_052575.1 (7996329..8031493)

    Chromosome 3 - NC_052534.1Genomic Context describing neighboring genes Neighboring gene polypeptide N-acetylgalactosaminyltransferase 14 Neighboring gene microRNA 1792 Neighboring gene uncharacterized LOC124418342 Neighboring gene lysocardiolipin acyltransferase 1 Neighboring gene uncharacterized LOC124417839 Neighboring gene LBH regulator of WNT signaling pathway

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcium-dependent cysteine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    calpain-13

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      8050658..8085858
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_004940180.5 → XP_004940237.3  calpain-13 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Z0X0, A0A8V0Z8B6
      Related
      ENSGALP00010024693.1, ENSGALT00010042156.1

    2. XM_040697452.2 → XP_040553386.1  calpain-13 isoform X3

      UniProtKB/TrEMBL
      A0A8V0Z0X0, A0A8V0Z890
      Related
      ENSGALP00010024668.1, ENSGALT00010042125.1
      Conserved Domains (4) summary
      smart00230
      Location:34 → 347
      CysPc; Calpain-like thiol protease family
      cd15897
      Location:502 → 530
      EFh_PEF; EF-hand motif [structural motif]
      cl25352
      Location:502 → 630
      EFh_PEF; The penta-EF hand (PEF) family
      cl00165
      Location:383 → 472
      Calpain_III; Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are ...

    3. XM_025149358.3 → XP_025005126.2  calpain-13 isoform X2

      UniProtKB/TrEMBL
      A0A8V0Z0X0, A0A8V0Z181
      Related
      ENSGALP00010024676.1, ENSGALT00010042136.1
      Conserved Domains (3) summary
      cd16195
      Location:496 → 663
      EFh_PEF_CAPN13_14; Penta-EF hand, calcium binding motifs, found in calpain-13 (CAPN13), calpain-14 (CAPN14), and similar proteins
      cl00051
      Location:34 → 341
      CysPc; Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction.
      cl00165
      Location:377 → 466
      Calpain_III; Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are ...

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      7996329..8031493
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040666535.2 → XP_040522469.1  calpain-13 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Z0X0
      Conserved Domains (3) summary
      smart00230
      Location:34 → 347
      CysPc; Calpain-like thiol protease family
      cd16195
      Location:502 → 669
      EFh_PEF_CAPN13_14; Penta-EF hand, calcium binding motifs, found in calpain-13 (CAPN13), calpain-14 (CAPN14), and similar proteins
      cl00165
      Location:383 → 472
      Calpain_III; Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are ...

    2. XM_040666537.2 → XP_040522471.1  calpain-13 isoform X3

      UniProtKB/TrEMBL
      A0A8V0Z0X0
      Conserved Domains (4) summary
      smart00230
      Location:34 → 347
      CysPc; Calpain-like thiol protease family
      cd15897
      Location:502 → 530
      EFh_PEF; EF-hand motif [structural motif]
      cl25352
      Location:502 → 630
      EFh_PEF; The penta-EF hand (PEF) family
      cl00165
      Location:383 → 472
      Calpain_III; Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are ...

    3. XM_040666536.2 → XP_040522470.1  calpain-13 isoform X2

      UniProtKB/TrEMBL
      A0A8V0Z0X0
      Conserved Domains (3) summary
      cd16195
      Location:496 → 663
      EFh_PEF_CAPN13_14; Penta-EF hand, calcium binding motifs, found in calpain-13 (CAPN13), calpain-14 (CAPN14), and similar proteins
      cl00051
      Location:34 → 341
      CysPc; Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction.
      cl00165
      Location:377 → 466
      Calpain_III; Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are ...
    Nucleotide Protein
    Heading Accession and Version

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