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    HEXA hexosaminidase subunit alpha [ Gallus gallus (chicken) ]

    Gene ID: 415320, updated on 10-Oct-2024

    Summary

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    Symbol
    HEXAprovided by CGNC
    Full Name
    hexosaminidase subunit alphaprovided by CGNC
    Primary source
    CGNC:49954
    See related
    Ensembl:ENSGALG00010021539
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See HEXA in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 10 NC_052541.1 (1647376..1664297, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 10 NC_052582.1 (1521207..1538143, complement)

    Chromosome 10 - NC_052541.1Genomic Context describing neighboring genes Neighboring gene poly(ADP-ribose) polymerase family member 6 Neighboring gene CUGBP Elav-like family member 6 Neighboring gene ariadne RBR E3 ubiquitin protein ligase 1 Neighboring gene Bardet-Biedl syndrome 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables beta-N-acetylhexosaminidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in ganglioside catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in glycosaminoglycan metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    beta-hexosaminidase subunit alpha
    Names
    hexosaminidase A (alpha polypeptide)
    NP_001025561.2
    XP_046754928.1
    XP_046780627.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001030390.2 → NP_001025561.2  beta-hexosaminidase subunit alpha precursor

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000245
      UniProtKB/TrEMBL
      A0A8V0ZD93, A0A8V0ZKK2, Q5ZI46
      Related
      ENSGALP00010031253.1, ENSGALT00010052313.1
      Conserved Domains (2) summary
      cd06562
      Location:166 → 508
      GH20_HexA_HexB-like; Beta-N-acetylhexosaminidases catalyze the removal of beta-1,4-linked N-acetyl-D-hexosamine residues from the non-reducing ends of N-acetyl-beta-D-hexosaminides including N-acetylglucosides and N-acetylgalactosides. The hexA and hexB genes encode the ...
      pfam14845
      Location:24 → 144
      Glycohydro_20b2; beta-acetyl hexosaminidase like

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052541.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      1647376..1664297 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046898972.1 → XP_046754928.1  beta-hexosaminidase subunit alpha isoform X1

      UniProtKB/TrEMBL
      A0A8V0ZD93

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052582.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      1521207..1538143 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046924671.1 → XP_046780627.1  beta-hexosaminidase subunit alpha isoform X2

    Nucleotide Protein Strain
    Heading Accession and Version

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    Molecular Biology Databases
    Research Materials