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    TRAM1 translocation associated membrane protein 1 [ Canis lupus familiaris (dog) ]

    Gene ID: 403948, updated on 17-Aug-2024

    Summary

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    Official Symbol
    TRAM1provided by VGNC
    Official Full Name
    translocation associated membrane protein 1provided by VGNC
    Primary source
    VGNC:VGNC:54123
    See related
    Ensembl:ENSCAFG00845026170
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Also known as
    TRAM
    Orthologs
    human mouse all
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    Genomic context

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    See TRAM1 in Genome Data Viewer
    Location:
    chromosome: 29
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 29 NC_051833.1 (19766644..19800987, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 29 NC_006611.4 (19929189..19963216, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 29 NC_049250.1 (20151950..20186017, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 29 NC_049289.1 (19804740..19838512, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 29 NC_049770.1 (19871008..19905124, complement)

    Chromosome 29 - NC_051833.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111093226 Neighboring gene spermine synthase-like Neighboring gene 40S ribosomal protein S8-like Neighboring gene XK related 9 Neighboring gene lactamase beta 2 Neighboring gene mitochondrial import inner membrane translocase subunit TIM14-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Signal sequence-dependent function of the TRAM protein during early phases of protein transport across the endoplasmic reticulum membrane. Voigt S, et al. J Cell Biol, 1996 Jul. PMID 8698819, Free PMC Article
    2. A protein of the endoplasmic reticulum involved early in polypeptide translocation. Görlich D, et al. Nature, 1992 May 7. PMID 1315422
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in SRP-dependent cotranslational protein targeting to membrane, translocation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein insertion into ER membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    translocating chain-associated membrane protein 1
    Names
    Protein TRAM1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001003267.1 → NP_001003267.1  translocating chain-associated membrane protein 1

      See identical proteins and their annotated locations for NP_001003267.1

      Status: PROVISIONAL

      Source sequence(s)
      X63678
      UniProtKB/Swiss-Prot
      Q01685
      UniProtKB/TrEMBL
      A0A8C0KVW7, A0A8C0TR87
      Related
      ENSCAFP00845036259.1, ENSCAFT00845046178.1
      Conserved Domains (2) summary
      smart00724
      Location:117 → 326
      TLC; TRAM, LAG1 and CLN8 homology domains
      pfam08390
      Location:50 → 115
      TRAM1; TRAM1-like protein

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051833.1 Reference ROS_Cfam_1.0

      Range
      19766644..19800987 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038441056.1 → XP_038296984.1  translocating chain-associated membrane protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0MSS9, A0A8C0TR29, A0A8I3S5U1
      Related
      ENSCAFP00845036372.1, ENSCAFT00845046318.1
      Conserved Domains (2) summary
      smart00724
      Location:117 → 350
      TLC; TRAM, LAG1 and CLN8 homology domains
      pfam08390
      Location:50 → 115
      TRAM1; TRAM1-like protein

    2. XM_038441057.1 → XP_038296985.1  translocating chain-associated membrane protein 1 isoform X2

      Conserved Domains (1) summary
      smart00724
      Location:21 → 254
      TLC; TRAM, LAG1 and CLN8 homology domains

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049289.1 Alternate UMICH_Zoey_3.1

      Range
      19804740..19838512 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049770.1 Alternate UNSW_CanFamBas_1.0

      Range
      19871008..19905124 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049250.1 Alternate UU_Cfam_GSD_1.0

      Range
      20151950..20186017 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006611.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      19929189..19963216 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q01685.2 GenPept UniProtKB/Swiss-Prot:Q01685

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