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    GNAQ G protein subunit alpha q [ Canis lupus familiaris (dog) ]

    Gene ID: 403928, updated on 17-Aug-2024

    Summary

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    Official Symbol
    GNAQprovided by VGNC
    Official Full Name
    G protein subunit alpha qprovided by VGNC
    Primary source
    VGNC:VGNC:41306
    See related
    Ensembl:ENSCAFG00845009564
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See GNAQ in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 1 NC_051805.1 (81038541..81345574)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 1 NC_006583.4 (81197285..81391732)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 1 NC_049222.1 (81383410..81578003)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 1 NC_049261.1 (80931602..81126112)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 1 NC_049742.1 (80652980..80847487)

    Chromosome 1 - NC_051805.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111096628 Neighboring gene uncharacterized LOC111096629 Neighboring gene uncharacterized LOC111096630 Neighboring gene uncharacterized LOC111096633 Neighboring gene G protein subunit alpha 14 Neighboring gene vacuolar protein sorting 13 homolog A Neighboring gene protein SET-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Modulation of Ca²+ activity in cardiomyocytes through caveolae-Gαq interactions. Guo Y, et al. Biophys J, 2011 Apr 6. PMID 21463572, Free PMC Article
    2. Specificity of G alpha q and G alpha 11 gene expression in platelets and erythrocytes. Expressions of cellular differentiation and species differences. Johnson GJ, et al. Biochem J, 1996 Sep 15. PMID 8836152, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables G protein-coupled receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables G-protein beta/gamma-subunit complex binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables guanyl nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in action potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in adenylate cyclase-modulating G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phospholipase C-activating dopamine receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of heterotrimeric G-protein complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    guanine nucleotide-binding protein G(q) subunit alpha
    Names
    G alpha q
    guanine nucleotide binding protein (G protein), q polypeptide
    guanine nucleotide-binding protein alpha-q

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001003249.1 → NP_001003249.1  guanine nucleotide-binding protein G(q) subunit alpha

      See identical proteins and their annotated locations for NP_001003249.1

      Status: VALIDATED

      Source sequence(s)
      JAAUVH010000354, L76257
      UniProtKB/Swiss-Prot
      Q28294
      Related
      ENSCAFP00845013101.1, ENSCAFT00845016843.1
      Conserved Domains (1) summary
      cd00066
      Location:1 → 295
      G-alpha; Alpha subunit of G proteins (guanine nucleotide binding)

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051805.1 Reference ROS_Cfam_1.0

      Range
      81038541..81345574
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038653399.1 → XP_038509327.1  guanine nucleotide-binding protein G(q) subunit alpha isoform X1

      UniProtKB/Swiss-Prot
      Q28294
      UniProtKB/TrEMBL
      A0A8C0LPJ6, A0A8C0M1E6
      Conserved Domains (1) summary
      cd00066
      Location:40 → 353
      G-alpha; Alpha subunit of G proteins (guanine nucleotide binding)

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049261.1 Alternate UMICH_Zoey_3.1

      Range
      80931602..81126112
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049742.1 Alternate UNSW_CanFamBas_1.0

      Range
      80652980..80847487
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049222.1 Alternate UU_Cfam_GSD_1.0

      Range
      81383410..81578003
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006583.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      81197285..81391732
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q28294.2 GenPept UniProtKB/Swiss-Prot:Q28294

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.