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    NRAS NRAS proto-oncogene, GTPase [ Canis lupus familiaris (dog) ]

    Gene ID: 403872, updated on 17-Aug-2024

    Summary

    Official Symbol
    NRASprovided by VGNC
    Official Full Name
    NRAS proto-oncogene, GTPaseprovided by VGNC
    Primary source
    VGNC:VGNC:43959
    See related
    Ensembl:ENSCAFG00845026380
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Also known as
    N-RAS; rasp21
    Orthologs
    NEW
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    Genomic context

    See NRAS in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 17 NC_051821.1 (53289080..53296149, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 17 NC_006599.4 (52062320..52069399, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 17 NC_049238.1 (52938741..52945813, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 17 NC_049277.1 (52323232..52330285, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 17 NC_049758.1 (52365409..52372486, complement)

    Chromosome 17 - NC_051821.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106559931 Neighboring gene adenosine monophosphate deaminase 1 Neighboring gene cold shock domain containing E1 Neighboring gene uncharacterized LOC111090677

    Genomic regions, transcripts, and products

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GDP binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in Ras protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    GTPase NRas
    Names
    neuroblastoma RAS viral oncogene homolog
    NP_001273994.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001287065.1NP_001273994.1  GTPase NRas

      See identical proteins and their annotated locations for NP_001273994.1

      Status: VALIDATED

      Source sequence(s)
      JAAUVH010000359
      UniProtKB/TrEMBL
      A0A8C0S2X6, A0A8C0S329, A0A8I3PSP7, A0A8I3PXY1
      Related
      ENSCAFP00845036549.1, ENSCAFT00845046556.1
      Conserved Domains (1) summary
      cd04138
      Location:3164
      H_N_K_Ras_like; Ras GTPase family containing H-Ras,N-Ras and K-Ras4A/4B

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051821.1 Reference ROS_Cfam_1.0

      Range
      53289080..53296149 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049277.1 Alternate UMICH_Zoey_3.1

      Range
      52323232..52330285 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049758.1 Alternate UNSW_CanFamBas_1.0

      Range
      52365409..52372486 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049238.1 Alternate UU_Cfam_GSD_1.0

      Range
      52938741..52945813 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006599.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      52062320..52069399 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)