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    COL4A3 collagen type IV alpha 3 chain [ Canis lupus familiaris (dog) ]

    Gene ID: 403842, updated on 17-Aug-2024

    Summary

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    Official Symbol
    COL4A3provided by VGNC
    Official Full Name
    collagen type IV alpha 3 chainprovided by VGNC
    Primary source
    VGNC:VGNC:59075
    See related
    Ensembl:ENSCAFG00845015636
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See COL4A3 in Genome Data Viewer
    Location:
    chromosome: 25
    Exon count:
    52
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 25 NC_051829.1 (40223476..40354004)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 25 NC_006607.4 (40594141..40724413)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 25 NC_049246.1 (40174823..40305251)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 25 NC_049285.1 (40160971..40291219)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 25 NC_049766.1 (40001099..40131636)

    Chromosome 25 - NC_051829.1Genomic Context describing neighboring genes Neighboring gene rhomboid domain containing 1 Neighboring gene uncharacterized LOC102157244 Neighboring gene collagen type IV alpha 4 chain Neighboring gene uncharacterized LOC102151715 Neighboring gene uncharacterized LOC102151666 Neighboring gene uncharacterized LOC111092350 Neighboring gene mitochondrial fission factor Neighboring gene transmembrane 4 L six family member 20

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Canine COL4A3 and COL4A4: sequencing, mapping and genomic organization. Wiersma AC, et al. DNA Seq, 2005 Aug. PMID 16147883
    2. Evaluation of canine COL4A3 and COL4A4 as candidates for familial renal disease in the Norwegian elkhound. Wiersma AC, et al. J Hered, 2005. PMID 16014809
    3. Haplotype sharing excludes orthologous COL4A3, COL4A4 or MYH9 loci in hereditary nephritis in bull terriers. O'Leary CA, et al. Anim Genet, 2009 Apr. PMID 19133935
    4. Coordinate gene expression of the alpha3, alpha4, and alpha5 chains of collagen type IV. Evidence from a canine model of X-linked nephritis with a COL4A5 gene mutation. Thorner PS, et al. J Biol Chem, 1996 Jun 7. PMID 8662866
    5. Immunohistochemical analysis of collagen types I, III, IV and alpha-actin in the urethra of sexually intact and ovariectomized beagles. Augsburger HR, et al. Int Urogynecol J Pelvic Floor Dysfunct, 2007 Sep. PMID 17206491

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables extracellular matrix structural constituent IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in basement membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of collagen trimer IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    collagen alpha-3(IV) chain; LOW QUALITY PROTEIN: collagen alpha-3(IV) chain

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051829.1 Reference ROS_Cfam_1.0

      Range
      40223476..40354004
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038435604.1 → XP_038291532.1  collagen alpha-3(IV) chain

      UniProtKB/TrEMBL
      A0A8I3NM06
      Related
      ENSCAFP00845021969.1, ENSCAFT00845027911.1
      Conserved Domains (2) summary
      pfam01391
      Location:1064 → 1118
      Collagen; Collagen triple helix repeat (20 copies)
      pfam01413
      Location:1446 → 1552
      C4; C-terminal tandem repeated domain in type 4 procollagen

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049285.1 Alternate UMICH_Zoey_3.1

      Range
      40160971..40291219
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038510536.1 → XP_038366464.1  LOW QUALITY PROTEIN: collagen alpha-3(IV) chain

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049766.1 Alternate UNSW_CanFamBas_1.0

      Range
      40001099..40131636
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038638313.1 → XP_038494241.1  collagen alpha-3(IV) chain

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049246.1 Alternate UU_Cfam_GSD_1.0

      Range
      40174823..40305251
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038573998.1 → XP_038429926.1  collagen alpha-3(IV) chain

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006607.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      40594141..40724413
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038458373.1 → XP_038314301.1  collagen alpha-3(IV) chain

      UniProtKB/TrEMBL
      A0A8P0NCG5
      Conserved Domains (2) summary
      pfam01391
      Location:1064 → 1118
      Collagen; Collagen triple helix repeat (20 copies)
      pfam01413
      Location:1446 → 1552
      C4; C-terminal tandem repeated domain in type 4 procollagen
    Nucleotide Protein Strain
    Heading Accession and Version

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