HTR1B 5-hydroxytryptamine receptor 1B [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: HTR1Bprovided by VGNC
Official Full Name: 5-hydroxytryptamine receptor 1Bprovided by VGNC
Primary source: VGNC:VGNC:110597
See related: Ensembl:ENSCAFG00845008653
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 12

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	12	NC_051816.1 (39430205..39431374, complement)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	12	NC_006594.4 (38541798..38542967, complement)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	12	NC_049233.1 (38869413..38870583, complement)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	12	NC_049272.1 (38755029..38756198, complement)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	12	NC_049753.1 (38739892..38741061, complement)

Chromosome 12 - NC_051816.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Gene does not play a major role in the variation in aggression in the Golden Retrievers.
Title: Evaluation of the serotonergic genes htr1A, htr1B, htr2A, and slc6A4 in aggressive behavior of golden retriever dogs.

Submit: New GeneRIF Correction

General gene information

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Markers

HTR1B (e-PCR)
- UniSTS:264058

GDB:580614 (e-PCR)
- UniSTS:157841

GDB:603584 (e-PCR)
- UniSTS:158177

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables G protein-coupled serotonin receptor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in adenylate cyclase-activating adrenergic receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in bone remodeling	IEA Inferred from Electronic Annotation more info	PubMed
involved_in chemical synaptic transmission	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of behavior	IEA Inferred from Electronic Annotation more info	PubMed
involved_in vasoconstriction	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: 5-hydroxytryptamine receptor 1B

Names: 5-HT-1B; 5-HT1B; 5-HT1D beta; 5-HT1D subtype beta; 5-HTR1B; 5-Hydroxytryptamine 1D receptor subtype beta; serotonin receptor 1B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001006948.1 → NP_001006949.1 5-hydroxytryptamine receptor 1B

Status: PROVISIONAL

Source sequence(s)

AB193090

UniProtKB/Swiss-Prot

P79250, Q6VVV0

UniProtKB/TrEMBL

A0A8C0KGB7

Related

ENSCAFP00845011816.1, ENSCAFT00845015216.1

Conserved Domains (1) summary

cd15333
Location:45 → 379

7tmA_5-HT1B_1D; serotonin receptor subtypes 1B and 1D, member of the class A family of seven-transmembrane G protein-coupled receptors