AFP alpha fetoprotein [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: AFPprovided by VGNC
Official Full Name: alpha fetoproteinprovided by VGNC
Primary source: VGNC:VGNC:37692
See related: Ensembl:ENSCAFG00845005947
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 13

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	13	NC_051817.1 (62992405..63012932)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	13	NC_006595.4 (61852491..61873033)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	13	NC_049234.1 (63232901..63253687)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	13	NC_049273.1 (62603973..62624508)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	13	NC_049754.1 (62097020..62117581)

Chromosome 13 - NC_051817.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

This study constitutes the first comprehensive study of p-glycoprotein, alpha-fetoprotein, and endothelial markers in canine hepatocellular carcinoma and cirrhosis.
Title: Cellular characterization of multidrug resistance P-glycoprotein, alpha fetoprotein, and neovascular endothelium-associated antigens in canine hepatocellular carcinoma and cirrhotic liver.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables fatty acid binding	IEA Inferred from Electronic Annotation more info	PubMed
enables zinc ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in transport	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in blood microparticle	IEA Inferred from Electronic Annotation more info	PubMed
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: alpha-fetoprotein

Names: alpha-1-fetoprotein; alpha-fetoglobulin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.