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    AP3B1 adaptor related protein complex 3 subunit beta 1 [ Canis lupus familiaris (dog) ]

    Gene ID: 403459, updated on 17-Aug-2024

    Summary

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    Official Symbol
    AP3B1provided by VGNC
    Official Full Name
    adaptor related protein complex 3 subunit beta 1provided by VGNC
    Primary source
    VGNC:VGNC:37963
    See related
    Ensembl:ENSCAFG00845008344
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See AP3B1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    32
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 3 NC_051807.1 (28405848..28672345)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 3 NC_006585.4 (29722995..29988777)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 3 NC_049224.1 (28647884..28914348)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 3 NC_049263.1 (28341769..28607713)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 3 NC_049744.1 (28320012..28585750)

    Chromosome 3 - NC_051807.1Genomic Context describing neighboring genes Neighboring gene secretory carrier membrane protein 1 Neighboring gene uncharacterized LOC106558577 Neighboring gene uncharacterized LOC111095167 Neighboring gene uncharacterized LOC111095353

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Light-activated BioID - an optically activated proximity labeling system to study protein-protein interactions. Shafraz O, et al. J Cell Sci, 2023 Oct 1. PMID 37756605, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in anterograde synaptic vesicle transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of AP-3 adaptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of clathrin adaptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of membrane coat IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    AP-3 complex subunit beta-1
    Names
    adapter-related protein complex 3 subunit beta-1
    adaptor protein complex AP-3 beta-1 subunit
    adaptor protein complex AP-3 subunit beta-1
    adaptor related protein complex 3 beta 1 subunit
    adaptor-related protein complex AP3 beta 1 subunit
    beta-3A-adaptin
    beta3A-adaptin
    clathrin assembly protein complex 3 beta-1 large chain

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001002974.2 → NP_001002974.1  AP-3 complex subunit beta-1

      See identical proteins and their annotated locations for NP_001002974.1

      Status: PROVISIONAL

      Source sequence(s)
      AY221640
      UniProtKB/Swiss-Prot
      Q7YRF1
      UniProtKB/TrEMBL
      A0A8C0RUP0
      Related
      ENSCAFP00845011565.1, ENSCAFT00845014918.1
      Conserved Domains (5) summary
      pfam01602
      Location:46 → 585
      Adaptin_N; Adaptin N terminal region
      pfam12717
      Location:128 → 251
      Cnd1; non-SMC mitotic condensation complex subunit 1
      pfam14796
      Location:811 → 955
      AP3B1_C; Clathrin-adaptor complex-3 beta-1 subunit C-terminal
      pfam14797
      Location:673 → 757
      SEEEED; Serine-rich region of AP3B1, clathrin-adaptor complex
      sd00044
      Location:116 → 144
      HEAT; HEAT repeat [structural motif]

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051807.1 Reference ROS_Cfam_1.0

      Range
      28405848..28672345
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038660423.1 → XP_038516351.1  AP-3 complex subunit beta-1 isoform X6

      UniProtKB/TrEMBL
      A0A8C0PLK8
      Conserved Domains (4) summary
      sd00044
      Location:116 → 144
      HEAT; HEAT repeat [structural motif]
      pfam14797
      Location:724 → 779
      SEEEED; Serine-rich region of AP3B1, clathrin-adaptor complex
      pfam01602
      Location:46 → 581
      Adaptin_N; Adaptin N terminal region
      pfam14796
      Location:810 → 856
      AP3B1_C; Clathrin-adaptor complex-3 beta-1 subunit C-terminal

    2. XM_038660421.1 → XP_038516349.1  AP-3 complex subunit beta-1 isoform X4

      UniProtKB/TrEMBL
      A0A8C0PLK8
      Conserved Domains (4) summary
      sd00044
      Location:116 → 144
      HEAT; HEAT repeat [structural motif]
      pfam14797
      Location:724 → 779
      SEEEED; Serine-rich region of AP3B1, clathrin-adaptor complex
      pfam01602
      Location:46 → 581
      Adaptin_N; Adaptin N terminal region
      pfam14796
      Location:810 → 955
      AP3B1_C; Clathrin-adaptor complex-3 beta-1 subunit C-terminal

    3. XM_038660422.1 → XP_038516350.1  AP-3 complex subunit beta-1 isoform X5

      UniProtKB/TrEMBL
      A0A8C0PLK8
      Conserved Domains (4) summary
      sd00044
      Location:116 → 144
      HEAT; HEAT repeat [structural motif]
      pfam14797
      Location:724 → 779
      SEEEED; Serine-rich region of AP3B1, clathrin-adaptor complex
      pfam01602
      Location:46 → 581
      Adaptin_N; Adaptin N terminal region
      pfam14796
      Location:810 → 955
      AP3B1_C; Clathrin-adaptor complex-3 beta-1 subunit C-terminal

    4. XM_038660419.1 → XP_038516347.1  AP-3 complex subunit beta-1 isoform X2

      UniProtKB/TrEMBL
      A0A8C0RUK5, A0A8P0NWU2
      Conserved Domains (4) summary
      sd00044
      Location:91 → 119
      HEAT; HEAT repeat [structural motif]
      pfam14797
      Location:699 → 754
      SEEEED; Serine-rich region of AP3B1, clathrin-adaptor complex
      pfam01602
      Location:46 → 556
      Adaptin_N; Adaptin N terminal region
      pfam14796
      Location:785 → 930
      AP3B1_C; Clathrin-adaptor complex-3 beta-1 subunit C-terminal

    5. XM_038660418.1 → XP_038516346.1  AP-3 complex subunit beta-1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0PKJ8, A0A8C0RUP0, A0A8I3N8P6
      Related
      ENSCAFP00845011401.1, ENSCAFT00845014714.1
      Conserved Domains (4) summary
      sd00044
      Location:116 → 144
      HEAT; HEAT repeat [structural motif]
      pfam14797
      Location:723 → 778
      SEEEED; Serine-rich region of AP3B1, clathrin-adaptor complex
      pfam01602
      Location:46 → 581
      Adaptin_N; Adaptin N terminal region
      pfam14796
      Location:809 → 954
      AP3B1_C; Clathrin-adaptor complex-3 beta-1 subunit C-terminal

    6. XM_038660420.1 → XP_038516348.1  AP-3 complex subunit beta-1 isoform X3

      UniProtKB/TrEMBL
      A0A8C0RUP0
      Conserved Domains (4) summary
      sd00044
      Location:89 → 117
      HEAT; HEAT repeat [structural motif]
      pfam14797
      Location:697 → 752
      SEEEED; Serine-rich region of AP3B1, clathrin-adaptor complex
      pfam01602
      Location:19 → 554
      Adaptin_N; Adaptin N terminal region
      pfam14796
      Location:783 → 928
      AP3B1_C; Clathrin-adaptor complex-3 beta-1 subunit C-terminal

    RNA

    1. XR_005423843.1 RNA Sequence

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049263.1 Alternate UMICH_Zoey_3.1

      Range
      28341769..28607713
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049744.1 Alternate UNSW_CanFamBas_1.0

      Range
      28320012..28585750
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049224.1 Alternate UU_Cfam_GSD_1.0

      Range
      28647884..28914348
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006585.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      29722995..29988777
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7YRF1.1 GenPept UniProtKB/Swiss-Prot:Q7YRF1

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