HADH hydroxyacyl-CoA dehydrogenase [Sus scrofa (pig)] - Gene

Summary

Official Symbol: HADHprovided by VGNC
Official Full Name: hydroxyacyl-CoA dehydrogenaseprovided by VGNC
Primary source: VGNC:VGNC:88771
See related: Ensembl:ENSSSCG00000009150
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Sus scrofa
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Also known as: HAD; HADHSC
Annotation information: Annotation category: partial on reference assembly
Expression: Ubiquitous expression in kidney (RPKM 211.0), heart (RPKM 190.0) and 8 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 8

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
106	current	Sscrofa11.1 (GCF_000003025.6)	8	NC_010450.4 (113952561..114005510, complement)
105	previous assembly	Sscrofa10.2 (GCF_000003025.5)	8	NC_010450.3 (122212898..122265850, complement)

Chromosome 8 - NC_010450.4 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
BioProject: PRJNA311523
Publication: PMID 27646534
Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables 3-hydroxyacyl-CoA dehydrogenase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables NAD+ binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in fatty acid beta-oxidation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in mitochondrion	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: hydroxyacyl-coenzyme A dehydrogenase, mitochondrial

Names: HCDH; L-3-hydroxyacyl-CoA dehydrogenase; medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase; short-chain 3-hydroxyacyl-CoA dehydrogenase

NP_999496.1

EC 1.1.1.35

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_214331.1 → NP_999496.1 hydroxyacyl-coenzyme A dehydrogenase, mitochondrial precursor

See identical proteins and their annotated locations for NP_999496.1

Status: PROVISIONAL

Source sequence(s)

AF027652

UniProtKB/Swiss-Prot

P00348, Q9XS66

UniProtKB/TrEMBL

A0A480WX09, A0A8D0KJJ7

Related

ENSSSCP00000053505.1, ENSSSCT00000049871.3

Conserved Domains (3) summary

COG1250
Location:27 → 313

FadB; 3-hydroxyacyl-CoA dehydrogenase [Lipid transport and metabolism]

pfam00725
Location:216 → 313

3HCDH; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain

pfam02737
Location:29 → 214

3HCDH_N; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain