DAO D-amino acid oxidase [Sus scrofa (pig)] - Gene

Summary

Official Symbol: DAOprovided by VGNC
Official Full Name: D-amino acid oxidaseprovided by VGNC
Primary source: VGNC:VGNC:87155
See related: Ensembl:ENSSSCG00000009942
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Sus scrofa
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Also known as: DAAO; DAO1; DAMOX
Annotation information: Annotation category: partial on reference assembly
Expression: Biased expression in kidney (RPKM 246.1), mixtures (RPKM 64.5) and 1 other tissue See more
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 14

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
106	current	Sscrofa11.1 (GCF_000003025.6)	14	NC_010456.5 (41931549..41950628, complement)
105	previous assembly	Sscrofa10.2 (GCF_000003025.5)	14	NC_010456.4 (44473515..44492595, complement)

Chromosome 14 - NC_010456.5 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Transcriptome data used for gene annotation
Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
BioProject: PRJNA311523
Publication: PMID 27646534
Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

DAO suppressed the growth of Staphylococcus aureus in a manner that depended on the concentration of DAO and D-amino acid in vitro; results suggest that DAO, together with myeloperoxidase, may play an important role in antibacterial systems in mammals
Title: Protective role of D-amino acid oxidase against Staphylococcus aureus infection.
catalyzes the oxidation of D-amino acid to imino acid and its three dimensional structure is determined.
Title: [Structure and reaction mechanism of D-amino acid oxidase].
The thermostable mutant DAO from porcine kidney by a single amino acid substitution, F42C, was stable at 55 degrees C, while the wild-type enzyme was stable only up to 45 degrees C.
Title: Thermostabilization of porcine kidney D-amino acid oxidase by a single amino acid substitution.
expression of Histamine N-Methyltransferase and Diamine Oxidase in porcine tissues
Title: Expression of histamine degrading enzymes in porcine tissues.

Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Markers

DAO-1 (e-PCR)
- UniSTS:253970

DAO (e-PCR)
- UniSTS:253505

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables D-amino-acid oxidase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables FAD binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in D-amino acid metabolic process	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: D-amino-acid oxidase

NP_999231.1

EC 1.4.3.3

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.