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    TNFRSF11B TNF receptor superfamily member 11b [ Gallus gallus (chicken) ]

    Gene ID: 378803, updated on 17-Aug-2024

    Summary

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    Symbol
    TNFRSF11Bprovided by CGNC
    Full Name
    TNF receptor superfamily member 11bprovided by CGNC
    Primary source
    CGNC:12044
    See related
    Ensembl:ENSGALG00010009219
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    OPG
    Orthologs
    human mouse all
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    Genomic context

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    See TNFRSF11B in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 2 NC_052533.1 (135324723..135342421, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 2 NC_052574.1 (135532760..135550446, complement)

    Chromosome 2 - NC_052533.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121109905 Neighboring gene uncharacterized LOC121109906 Neighboring gene collectin subfamily member 10 Neighboring gene mal, T-cell differentiation protein 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Effects of manganese deficiency on the microstructure of proximal tibia and OPG/RANKL gene expression in chicks. Liu R, et al. Vet Res Commun, 2015 Mar. PMID 25634035
    2. Characterization of chicken TNFR superfamily decoy receptors, DcR3 and osteoprotegerin. Bridgham JT, et al. Biochem Biophys Res Commun, 2003 Aug 8. PMID 12878204

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tumor necrosis factor receptor superfamily member 11B
    Names
    tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001033641.2 → NP_001028813.2  tumor necrosis factor receptor superfamily member 11B precursor

      Status: PROVISIONAL

      Source sequence(s)
      JAENSK010000044
      UniProtKB/TrEMBL
      A0A8V0Y2R7, Q4F9K2
      Related
      ENSGALP00010012607.1, ENSGALT00010021999.1
      Conserved Domains (4) summary
      smart00005
      Location:289 → 354
      DEATH; DEATH domain, found in proteins involved in cell death (apoptosis)
      cd01670
      Location:223 → 291
      Death; Death Domain: a protein-protein interaction domain
      cd00185
      Location:124 → 186
      TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)
      cd10581
      Location:6 → 152
      TNFRSF11B; Tumor necrosis factor receptor superfamily member 11B (TNFRSF11B), also known as Osteoprotegerin (OPG)

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052533.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      135324723..135342421 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015283019.4 → XP_015138505.1  tumor necrosis factor receptor superfamily member 11B isoform X1

      UniProtKB/TrEMBL
      A0A3Q2U211, A0A8V0Y2R3
      Related
      ENSGALP00010012615.1, ENSGALT00010022009.1
      Conserved Domains (3) summary
      cd00185
      Location:85 → 147
      TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)
      pfam00531
      Location:251 → 327
      Death; Death domain
      cl22855
      Location:1 → 113
      TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052574.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      135532760..135550446 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046910215.1 → XP_046766171.1  tumor necrosis factor receptor superfamily member 11B isoform X1

      UniProtKB/TrEMBL
      A0A3Q2U211, A0A8V0Y2R3
    Nucleotide Protein Strain
    Heading Accession and Version

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