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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001013246.2 → NP_001013264.2 rho guanine nucleotide exchange factor 12
Status: VALIDATED
- Source sequence(s)
-
JAXUCZ010000008
- UniProtKB/TrEMBL
-
Q5BMA6
- Related
- ENSRNOP00000074482.2, ENSRNOT00000081007.3
- Conserved Domains (4) summary
-
- cd08754
Location:349 → 570
- RGS_LARG; Regulator of G protein signaling (RGS) domain found in the leukemia-associated Rho guanine nucleotide exchange factor (RhoGEF) protein (LARG)
- smart00325
Location:791 → 976
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
- cd00992
Location:71 → 145
- PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
- cd13390
Location:995 → 1132
- PH_LARG; Leukemia-associated Rho guanine nucleotide exchange factor Pleckstrin homology (PH) domain
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCr8
Genomic
-
NC_086026.1 Reference GRCr8
- Range
-
52247047..52373158 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_039081856.2 → XP_038937784.1 rho guanine nucleotide exchange factor 12 isoform X1
- UniProtKB/TrEMBL
- D3ZYR0, Q5BMA6
- Related
- ENSRNOP00000056613.5, ENSRNOT00000059868.6
- Conserved Domains (4) summary
-
- cd08754
Location:330 → 551
- RGS_LARG; Regulator of G protein signaling (RGS) domain found in the leukemia-associated Rho guanine nucleotide exchange factor (RhoGEF) protein (LARG)
- smart00325
Location:772 → 957
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
- cd00992
Location:52 → 126
- PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
- cd13390
Location:976 → 1113
- PH_LARG; Leukemia-associated Rho guanine nucleotide exchange factor Pleckstrin homology (PH) domain
-
XM_063265873.1 → XP_063121943.1 rho guanine nucleotide exchange factor 12 isoform X2
-
XM_063265874.1 → XP_063121944.1 rho guanine nucleotide exchange factor 12 isoform X3