Zdhhc13 zinc finger DHHC-type palmitoyltransferase 13 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Zdhhc13provided by RGD
Official Full Name: zinc finger DHHC-type palmitoyltransferase 13provided by RGD
Primary source: RGD:1309736
See related: EnsemblRapid:ENSRNOG00000014277 AllianceGenome:RGD:1309736
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable magnesium ion transmembrane transporter activity and protein-cysteine S-palmitoyltransferase activity. Predicted to be involved in positive regulation of canonical NF-kappaB signal transduction and protein targeting to membrane. Predicted to be located in Golgi apparatus; Golgi-associated vesicle membrane; and endoplasmic reticulum. Predicted to be active in Golgi membrane. Orthologous to human ZDHHC13 (zinc finger DHHC-type palmitoyltransferase 13). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Kidney (RPKM 109.7), Spleen (RPKM 84.0) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 1q22

Exon count:: 17

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (107623599..107662178)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (98487319..98525906)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (104106211..104145045)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH139123 (e-PCR)
- UniSTS:221209

RH131848 (e-PCR)
- UniSTS:215131

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables magnesium ion transmembrane transporter activity	ISO Inferred from Sequence Orthology more info
enables palmitoyltransferase activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in magnesium ion transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of canonical NF-kappaB signal transduction	ISO Inferred from Sequence Orthology more info	PubMed

Component	Evidence Code	Pubs
located_in Golgi apparatus	ISO Inferred from Sequence Orthology more info
located_in Golgi membrane	ISO Inferred from Sequence Orthology more info
located_in Golgi-associated vesicle membrane	ISO Inferred from Sequence Orthology more info
located_in endoplasmic reticulum	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: palmitoyltransferase ZDHHC13

Names: probable palmitoyltransferase ZDHHC13; zinc finger, DHHC domain containing 13; zinc finger, DHHC-type containing 13

NP_001382044.1

EC 2.3.1.225

XP_038940918.1

EC 2.3.1.225

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001395115.1 → NP_001382044.1 palmitoyltransferase ZDHHC13

Status: VALIDATED

Source sequence(s)

JAXUCZ010000001

UniProtKB/TrEMBL

A6JBF2, E9PU37

Related

ENSRNOP00000019175.4, ENSRNOT00000019175.7

Conserved Domains (3) summary

sd00045
Location:81 → 112

ANK; ANK repeat [structural motif]

pfam01529
Location:423 → 557

DHHC; DHHC palmitoyltransferase

cl39094
Location:66 → 269

Ank_2; Ankyrin repeats (3 copies)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086019.1 Reference GRCr8

Range

107623599..107662178

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_039084990.2 → XP_038940918.1 palmitoyltransferase ZDHHC13 isoform X1

Conserved Domains (3) summary

COG0666
Location:15 → 141

ANKYR; Ankyrin repeat [Signal transduction mechanisms]

sd00045
Location:18 → 49

ANK; ANK repeat [structural motif]

pfam01529
Location:293 → 427

DHHC; DHHC palmitoyltransferase

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_001039037.1: Suppressed sequence

Description

NM_001039037.1: This RefSeq record was removed by NCBI staff. Contact info@ncbi.nlm.nih.gov for further information.