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    Ppp1r16a protein phosphatase 1, regulatory subunit 16A [ Rattus norvegicus (Norway rat) ]

    Gene ID: 362944, updated on 2-Nov-2024

    Summary

    Official Symbol
    Ppp1r16aprovided by RGD
    Official Full Name
    protein phosphatase 1, regulatory subunit 16Aprovided by RGD
    Primary source
    RGD:1307962
    See related
    EnsemblRapid:ENSRNOG00000015450 AllianceGenome:RGD:1307962
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable enzyme inhibitor activity and myosin phosphatase regulator activity. Predicted to be located in plasma membrane. Predicted to be active in cytoplasm. Orthologous to human PPP1R16A (protein phosphatase 1 regulatory subunit 16A). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Lung (RPKM 91.0), Kidney (RPKM 63.1) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Ppp1r16a in Genome Data Viewer
    Location:
    7q34
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (110272307..110295452)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (108391664..108414812)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (117734002..117757249)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene Tmem276-zftraf1 readthrough Neighboring gene Transmembrane protein 276 Neighboring gene kinesin family member C2 Neighboring gene forkhead box H1 Neighboring gene glutamic--pyruvic transaminase Neighboring gene major facilitator superfamily domain containing 3 Neighboring gene RecQ like helicase 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables enzyme inhibitor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables myosin phosphatase regulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    protein phosphatase 1 regulatory subunit 16A
    Names
    protein phosphatase 1, regulatory (inhibitor) subunit 16A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001130566.1NP_001124038.1  protein phosphatase 1 regulatory subunit 16A

      See identical proteins and their annotated locations for NP_001124038.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473950
      UniProtKB/TrEMBL
      A0A8I6A2T7, A6HSC4
      Related
      ENSRNOP00000020768.2, ENSRNOT00000020768.5
      Conserved Domains (4) summary
      cd00204
      Location:99286
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:76168
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:205253
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:75102
      ANK; ANK repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      110272307..110295452
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063263876.1XP_063119946.1  protein phosphatase 1 regulatory subunit 16A isoform X1

      UniProtKB/TrEMBL
      D3ZVR8