Trim7 tripartite motif-containing 7 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Trim7provided by RGD
Official Full Name: tripartite motif-containing 7provided by RGD
Primary source: RGD:1307328
See related: EnsemblRapid:ENSRNOG00000002469 AllianceGenome:RGD:1307328
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in antiviral innate immune response. Predicted to be located in nucleus. Predicted to be active in cytoplasm. Orthologous to human TRIM7 (tripartite motif containing 7). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Testes (RPKM 145.2), Muscle (RPKM 138.4) and 7 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 10q21

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	10	NC_086028.1 (33706614..33722609)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	10	NC_051345.1 (33205491..33221482)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	10	NC_005109.4 (34185535..34200750)

Chromosome 10 - NC_086028.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables ubiquitin protein ligase activity	IBA Inferred from Biological aspect of Ancestor more info
enables ubiquitin protein ligase activity	ISO Inferred from Sequence Orthology more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in antiviral innate immune response	ISO Inferred from Sequence Orthology more info
involved_in innate immune response	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
is_active_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in nucleus	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: E3 ubiquitin-protein ligase TRIM7

Names: tripartite motif protein 7; tripartite motif-containing protein 7

NP_001385696.1

EC 2.3.2.27

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001398767.1 → NP_001385696.1 E3 ubiquitin-protein ligase TRIM7

Status: VALIDATED

Source sequence(s)

JAXUCZ010000010

UniProtKB/TrEMBL

D3ZNJ9

Related

ENSRNOP00000003339.5, ENSRNOT00000003339.7

Conserved Domains (5) summary

COG1196
Location:167 → 284

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

cd13740
Location:344 → 510

SPRY_PRY_TRIM7; PRY/SPRY domain in tripartite motif-binding protein 7 (TRIM7)

cd00162
Location:29 → 80

RING_Ubox; RING-HC finger (C3HC4-type) [structural motif]

cd19762
Location:128 → 170

Bbox2_TRIM7-like; B-box-type 2 zinc finger found in tripartite motif-containing proteins TRIM7, TRIM27 and similar proteins

cl17238
Location:26 → 81

RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain