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    Phkg1 phosphorylase kinase catalytic subunit gamma 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 29353, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Phkg1provided by RGD
    Official Full Name
    phosphorylase kinase catalytic subunit gamma 1provided by RGD
    Primary source
    RGD:3325
    See related
    EnsemblRapid:ENSRNOG00000000920 AllianceGenome:RGD:3325
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Phkg; PHKIN01
    Summary
    Enables ATP binding activity; enzyme binding activity; and phosphorylase kinase activity. Involved in glycogen metabolic process and protein phosphorylation. Part of phosphorylase kinase complex. Orthologous to human PHKG1 (phosphorylase kinase catalytic subunit gamma 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Muscle (RPKM 1156.5) and Heart (RPKM 84.7) See more
    Orthologs
    human mouse all
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    Genomic context

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    See Phkg1 in Genome Data Viewer
    Location:
    12q13
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (32474926..32490657)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (26838822..26854547)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (30450431..30464314)

    Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene MLV-related proviral Env polyprotein-like Neighboring gene protein NYNRIN-like Neighboring gene coiled-coil-helix-coiled-coil-helix domain containing 2 Neighboring gene sulfatase modifying factor 2 Neighboring gene uncharacterized LOC120095933 Neighboring gene small nucleolar RNA SNORA15 Neighboring gene chaperonin containing TCP1 subunit 6A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Characterization of the gene for rat phosphorylase kinase catalytic subunit. Cawley KC, et al. J Biol Chem, 1993 Jan 15. PMID 8419323
    2. Nucleotide sequence of cDNA encoding the catalytic subunit of phosphorylase kinase from rat soleus muscle. Cawley KC, et al. Nucleic Acids Res, 1988 Mar 25. PMID 3357797, Free PMC Article
    3. Comparison of glycogen phosphorylase kinases of various rat tissues. Taira T, et al. J Biochem, 1982 Mar. PMID 6281247
    4. Rat skeletal muscle phosphorylase kinase: turnover and control of isozyme levels in culture. Salsgiver WJ, et al. Am J Physiol, 1986 Mar. PMID 3953807
    5. Phosphorylase kinase: the complexity of its regulation is reflected in the complexity of its structure. Brushia RJ, et al. Front Biosci, 1999 Sep 15. PMID 10487978

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables ATP binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables calmodulin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables enzyme binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables histone H2AS1 kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphorylase kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phosphorylase kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables phosphorylase kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphorylase kinase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables phosphorylase kinase activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables protein serine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables tau-protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in chromatin remodeling IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in glycogen metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in glycogen metabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in glycogen metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in glycogen metabolic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in protein phosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of phosphorylase kinase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of phosphorylase kinase complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of phosphorylase kinase complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of phosphorylase kinase complex TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform
    Names
    gamma phosphorylase kinase
    phosphorylase kinase subunit gamma-1
    phosphorylase kinase, gamma 1
    serine/threonine-protein kinase PHKG1
    NP_113761.1
    XP_038945214.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_031573.2 → NP_113761.1  phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform

      See identical proteins and their annotated locations for NP_113761.1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000012
      UniProtKB/Swiss-Prot
      P13286
      UniProtKB/TrEMBL
      A0A8I5ZWH7, A6J0P5
      Related
      ENSRNOP00000001222.1, ENSRNOT00000001222.6
      Conserved Domains (1) summary
      cl21453
      Location:16 → 291
      PKc_like; Protein Kinases, catalytic domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086030.1 Reference GRCr8

      Range
      32474926..32490657
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039089286.2 → XP_038945214.1  phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZWH7
      Conserved Domains (1) summary
      cl21453
      Location:16 → 281
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P13286.2 GenPept UniProtKB/Swiss-Prot:P13286

    Gene LinkOut

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