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    Itgb3 integrin subunit beta 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 29302, updated on 28-Oct-2024

    Summary

    Official Symbol
    Itgb3provided by RGD
    Official Full Name
    integrin subunit beta 3provided by RGD
    Primary source
    RGD:628868
    See related
    EnsemblRapid:ENSRNOG00000048449 AllianceGenome:RGD:628868
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    GPIIIa
    Summary
    Contributes to fibrinogen binding activity. Involved in several processes, including positive regulation of cell migration; positive regulation of cell population proliferation; and positive regulation of signal transduction. Located in apical plasma membrane; cell surface; and focal adhesion. Part of integrin complex. Is active in glycinergic synapse. Biomarker of bacterial pneumonia; glomerulonephritis; and transient cerebral ischemia. Human ortholog(s) of this gene implicated in several diseases, including acute myeloid leukemia; autoimmune thrombocytopenic purpura; blood platelet disease (multiple); end stage renal disease; and non-arteritic anterior ischemic optic neuropathy. Orthologous to human ITGB3 (integrin subunit beta 3). [provided by Alliance of Genome Resources, Oct 2024]
    Expression
    Biased expression in Spleen (RPKM 209.8), Liver (RPKM 99.9) and 7 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Itgb3 in Genome Data Viewer
    Location:
    10q32.1
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (90009927..90067787)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (89509917..89564679)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (92667869..92783413)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene cell division cycle 27 Neighboring gene myosin, light chain 4 Neighboring gene glutathione S-transferase pi 1, pseudogene 2 Neighboring gene uncharacterized LOC134480888 Neighboring gene EF-hand calcium binding domain 3 Neighboring gene uncharacterized LOC108352141

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables C-X3-C chemokine binding IEA
    Inferred from Electronic Annotation
    more info
     
    contributes_to C-X3-C chemokine binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables cell adhesion molecule binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables enzyme binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables extracellular matrix binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables extracellular matrix binding ISO
    Inferred from Sequence Orthology
    more info
     
    contributes_to fibrinogen binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    contributes_to fibrinogen binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables fibroblast growth factor binding IEA
    Inferred from Electronic Annotation
    more info
     
    contributes_to fibroblast growth factor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables fibronectin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables fibronectin binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables fibronectin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables identical protein binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables insulin-like growth factor I binding IEA
    Inferred from Electronic Annotation
    more info
     
    contributes_to insulin-like growth factor I binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables integrin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables integrin binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables integrin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables neuregulin binding IEA
    Inferred from Electronic Annotation
    more info
     
    contributes_to neuregulin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protease binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protease binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein disulfide isomerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein disulfide isomerase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein kinase C binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein kinase C binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables vascular endothelial growth factor receptor 2 binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables vascular endothelial growth factor receptor 2 binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in activation of protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in activation of protein kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in apolipoprotein A-I-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in apolipoprotein A-I-mediated signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in apoptotic cell clearance IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in apoptotic cell clearance ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in blood coagulation, fibrin clot formation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within blood coagulation, fibrin clot formation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cell adhesion IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cell adhesion TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in cell adhesion mediated by integrin IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in cell adhesion mediated by integrin IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cell adhesion mediated by integrin ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cell migration IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in cell-matrix adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in cell-matrix adhesion IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cell-matrix adhesion ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cell-matrix adhesion ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cell-substrate adhesion ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cell-substrate junction assembly IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cell-substrate junction assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cellular response to insulin-like growth factor stimulus IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in cellular response to mechanical stimulus IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in cellular response to platelet-derived growth factor stimulus IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cellular response to platelet-derived growth factor stimulus ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cellular response to xenobiotic stimulus IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in embryo implantation IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in heterotypic cell-cell adhesion IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in heterotypic cell-cell adhesion ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in integrin-mediated signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in integrin-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in maintenance of postsynaptic specialization structure EXP
    Inferred from Experiment
    more info
    PubMed 
    involved_in maintenance of postsynaptic specialization structure IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in mesodermal cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mesodermal cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative chemotaxis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in negative chemotaxis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of endothelial cell apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of lipid storage IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in negative regulation of lipid storage ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of lipid transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in negative regulation of lipid transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of lipoprotein metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in negative regulation of lipoprotein metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of low-density lipoprotein receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within negative regulation of low-density lipoprotein receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of macrophage derived foam cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in negative regulation of macrophage derived foam cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in platelet activation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in platelet aggregation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in platelet aggregation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within platelet aggregation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in platelet aggregation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in platelet-derived growth factor receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within platelet-derived growth factor receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of ERK1 and ERK2 cascade IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of T cell migration IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of T cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of angiogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of bone resorption IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of cell adhesion mediated by integrin IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of cell-matrix adhesion IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within positive regulation of cell-matrix adhesion ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of endothelial cell migration IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of endothelial cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of endothelial cell proliferation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of endothelial cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of fibroblast migration IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of fibroblast migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within positive regulation of fibroblast migration ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of fibroblast proliferation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within positive regulation of fibroblast proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of gene expression IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of gene expression ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of glomerular mesangial cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of leukocyte migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of osteoblast proliferation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of osteoblast proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of peptidyl-tyrosine phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of peptidyl-tyrosine phosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of smooth muscle cell migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of smooth muscle cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of substrate adhesion-dependent cell spreading IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within positive regulation of substrate adhesion-dependent cell spreading ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of G protein-coupled receptor signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of actin cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of actin cytoskeleton organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of extracellular matrix organization IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within regulation of extracellular matrix organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of postsynaptic neurotransmitter receptor diffusion trapping EXP
    Inferred from Experiment
    more info
    PubMed 
    involved_in regulation of postsynaptic neurotransmitter receptor diffusion trapping IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in regulation of postsynaptic neurotransmitter receptor internalization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of postsynaptic neurotransmitter receptor internalization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of protein localization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of protein localization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of protein localization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within regulation of protein tyrosine kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of release of sequestered calcium ion into cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in regulation of serotonin uptake IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of serotonin uptake ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of serotonin uptake ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of trophoblast cell migration IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within regulation of trophoblast cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in response to activity IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in response to platelet-derived growth factor IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in smooth muscle cell migration IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in smooth muscle cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in substrate adhesion-dependent cell spreading IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in substrate adhesion-dependent cell spreading ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in symbiont entry into host cell IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of alpha9-beta1 integrin-ADAM8 complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of alpha9-beta1 integrin-ADAM8 complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of alphav-beta3 integrin-HMGB1 complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of alphav-beta3 integrin-HMGB1 complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of alphav-beta3 integrin-IGF-1-IGF1R complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of alphav-beta3 integrin-IGF-1-IGF1R complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of alphav-beta3 integrin-PKCalpha complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of alphav-beta3 integrin-PKCalpha complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in apical plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in apical plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in apical plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in cell surface IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cell surface IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cell surface ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cell-cell junction IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cell-cell junction ISO
    Inferred from Sequence Orthology
    more info
     
    located_in external side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in external side of plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in filopodium membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in filopodium membrane ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in focal adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in focal adhesion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in focal adhesion IEA
    Inferred from Electronic Annotation
    more info
     
    located_in focal adhesion ISO
    Inferred from Sequence Orthology
    more info
     
    located_in glutamatergic synapse IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in glutamatergic synapse ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in glycinergic synapse EXP
    Inferred from Experiment
    more info
    PubMed 
    is_active_in glycinergic synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of integrin alphaIIb-beta3 complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of integrin alphaIIb-beta3 complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of integrin alphav-beta3 complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of integrin alphav-beta3 complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of integrin complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of integrin complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of integrin complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in lamellipodium membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in lamellipodium membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in melanosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in melanosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in microvillus membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in microvillus membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane TAS
    Traceable Author Statement
    more info
     
    located_in postsynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
     
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of receptor complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in ruffle membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in ruffle membrane ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in synapse IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in synapse ISO
    Inferred from Sequence Orthology
    more info
     
    located_in synapse ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in synaptic membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in synaptic membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    integrin beta-3
    Names
    integrin beta 3 (Cd61)
    integrin, beta 3
    platelet membrane glycoprotein IIIa

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_153720.2NP_714942.1  integrin beta-3 precursor

      See identical proteins and their annotated locations for NP_714942.1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/Swiss-Prot
      M0RCF3, Q8R2H2
      UniProtKB/TrEMBL
      A0A0G2JWK0
      Related
      ENSRNOP00000067271.3, ENSRNOT00000073350.4
      Conserved Domains (4) summary
      smart00187
      Location:37460
      INB; Integrin beta subunits (N-terminal portion of extracellular region)
      pfam07965
      Location:633716
      Integrin_B_tail; Integrin beta tail domain
      pfam08725
      Location:743785
      Integrin_b_cyt; Integrin beta cytoplasmic domain
      pfam18372
      Location:462491
      I-EGF_1; Integrin beta epidermal growth factor like domain 1

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      90009927..90067787
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063268800.1XP_063124870.1  integrin beta-3 isoform X1

      Related
      ENSRNOP00000108816.1, ENSRNOT00000125492.1