Oxgr1 oxoglutarate receptor 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Oxgr1provided by RGD
Official Full Name: oxoglutarate receptor 1provided by RGD
Primary source: RGD:1303155
See related: EnsemblRapid:ENSRNOG00000075479 AllianceGenome:RGD:1303155
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Gpr80; P2Y15
Summary: Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in calcium oxalate nephrolithiasis. Orthologous to human OXGR1 (oxoglutarate receptor 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Restricted expression toward (RPKM 43.6) See more
Orthologs: human mouse all
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Genomic context

Location:: 15q24

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	15	NC_086033.1 (103551338..103573611, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	15	NC_051350.1 (97145947..97146960, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	15	NC_005114.4 (105399596..105422559, complement)

Chromosome 15 - NC_086033.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

P2Y15 is a cell surface receptor for AMP and adenosine
Title: Identification and characterization of a cell-surface receptor, P2Y15, for AMP and adenosine.

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables G protein-coupled receptor activity	ISO Inferred from Sequence Orthology more info
enables G protein-coupled receptor activity	ISS Inferred from Sequence or Structural Similarity more info
enables signaling receptor activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in biological_process	ND No biological Data available more info

Component	Evidence Code	Pubs
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	ISO Inferred from Sequence Orthology more info
located_in plasma membrane	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: 2-oxoglutarate receptor 1

Names: G protein-coupled receptor 80; P2Y purinoceptor 15; alpha-ketoglutarate receptor 1; oxoglutarate (alpha-ketoglutarate) receptor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_207588.1 → NP_997471.1 2-oxoglutarate receptor 1

See identical proteins and their annotated locations for NP_997471.1

Status: PROVISIONAL

Source sequence(s)

AY191367

UniProtKB/Swiss-Prot

Q6Y1R5

UniProtKB/TrEMBL

A6HUH9

Related

ENSRNOP00000098804.1, ENSRNOT00000150824.1

Conserved Domains (1) summary

cd15375
Location:35 → 313

7tmA_OXGR1; 2-oxoglutarate receptor 1, member of the class A family of seven-transmembrane G protein-coupled receptors