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    Evx2 even-skipped homeobox 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 288155, updated on 2-Nov-2024

    Summary

    Official Symbol
    Evx2provided by RGD
    Official Full Name
    even-skipped homeobox 2provided by RGD
    Primary source
    RGD:1305594
    See related
    EnsemblRapid:ENSRNOG00000001589 AllianceGenome:RGD:1305594
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within limb morphogenesis. Predicted to be active in nucleus. Orthologous to human EVX2 (even-skipped homeobox 2). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Low expression observed in reference dataset See more
    Orthologs
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    Genomic context

    See Evx2 in Genome Data Viewer
    Location:
    3q23
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (79965630..79969700, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (59558197..59562267, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (61564917..61581598, complement)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein S26, pseudogene 2 Neighboring gene U6 spliceosomal RNA Neighboring gene prothymosin alpha, pseudogene 8 Neighboring gene homeo box D13 Neighboring gene homeo box D12

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    homeobox even-skipped homolog protein 2
    Names
    even skipped homeotic gene 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      79965630..79969700 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_221512.9XP_221512.6  homeobox even-skipped homolog protein 2

      UniProtKB/TrEMBL
      D4ACC8
      Related
      ENSRNOP00000002156.5, ENSRNOT00000002156.6
      Conserved Domains (1) summary
      pfam00046
      Location:194247
      Homeobox; Homeobox domain