CD9 CD9 molecule [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: CD9provided by VGNC
Official Full Name: CD9 moleculeprovided by VGNC
Primary source: VGNC:VGNC:27053
See related: BGD:BT24423; Ensembl:ENSBTAG00000014764
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 5

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	5	NC_037332.1 (104123604..104159285, complement)

Chromosome 5 - NC_037332.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:: NC_037332.1 Chromosome 5 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The aim of this study was to compare the localization of CD9 and CD81 tetraspanins during oocyte maturation and early development of the embryos in bovine and porcine model.
Title: Detection of CD9 and CD81 tetraspanins in bovine and porcine oocytes and embryos.
Tests showed that the vitrification/warming procedures significantly decreased CD9 expression at the mRNA and protein levels, and changed the CD9 distribution pattern in bovine oocytes.
Title: Decreased expression of CD9 in bovine oocytes after cryopreservation and the relationship to fertilization capacity.
CD9 present on bovine matured oocytes is involved in sperm-oocyte interaction during fertilization.
Title: Tetraspanin CD9 in bovine oocytes and its role in fertilization.
Immortalized microvascular endothelial cells of the bovine retina express members of the tetraspanin family of which CD9 was demonstrated to have a function in migration and adhesion of these cells.
Title: Tetraspanin CD9 is involved in the migration of retinal microvascular endothelial cells.

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General gene information

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Markers

BMS772 (e-PCR), detects polymorphism
- UniSTS:80680

HAUT29 (e-PCR), detects polymorphism
- UniSTS:251533

CD9 (e-PCR), detects polymorphism
- UniSTS:278179

Gene Ontology Provided by RefSeq

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: CD9 antigen

Names: CD9 antigen (p24)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_173900.2 → NP_776325.1 CD9 antigen

See identical proteins and their annotated locations for NP_776325.1

Status: PROVISIONAL

Source sequence(s)

M81720

UniProtKB/Swiss-Prot

A6QLK0, P30932

UniProtKB/TrEMBL

A0AAF6Z0W1

Related

ENSBTAP00000019643.6, ENSBTAT00000019643.6

Conserved Domains (2) summary

cd03152
Location:109 → 191

CD9_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), CD9 family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model spans ...

pfam00335
Location:9 → 219

Tetraspannin; Tetraspanin family