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Dlg2 discs large MAGUK scaffold protein 2 [ Mus musculus (house mouse) ]

Gene ID: 23859, updated on 28-Oct-2024

Summary

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Official Symbol: Dlg2provided by MGI
Official Full Name: discs large MAGUK scaffold protein 2provided by MGI
Primary source: MGI:MGI:1344351
See related: Ensembl:ENSMUSG00000052572 AllianceGenome:MGI:1344351
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Dlgh2; PSD93; Gm1197; Gm21505; A330103J02Rik; B230218P12Rik; B330007M19Rik
Summary: A structural constituent of postsynaptic density. Involved in several processes, including axo-dendritic protein transport; clustering of voltage-gated potassium channels; and neurotransmitter receptor localization to postsynaptic specialization membrane. Acts upstream of or within chemical synaptic transmission and sensory perception of pain. Located in several cellular components, including juxtaparanode region of axon; postsynaptic membrane; and synaptic vesicle membrane. Is active in axon initial segment and glutamatergic synapse. Is expressed in jaw bone; nervous system; and retina. Orthologous to human DLG2 (discs large MAGUK scaffold protein 2). [provided by Alliance of Genome Resources, Oct 2024]
Expression: Biased expression in frontal lobe adult (RPKM 12.3), cortex adult (RPKM 11.4) and 5 other tissues See more
Orthologs: human all
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Genomic context

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See Dlg2 in Genome Data Viewer

Location:: 7 E1; 7 51.07 cM

Exon count:: 40

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	7	NC_000073.7 (90125399..92098454)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	7	NC_000073.6 (90476188..92449246)

Chromosome 7 - NC_000073.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Selective behavioural impairments in mice heterozygous for the cross disorder psychiatric risk gene DLG2.
Title: Selective behavioural impairments in mice heterozygous for the cross disorder psychiatric risk gene DLG2.
MAGUKs are essential, but redundant, in long-term potentiation.
Title: MAGUKs are essential, but redundant, in long-term potentiation.
PSD-93 mediates the crosstalk between neuron and microglia and facilitates acute ischemic stroke injury by binding to CX3CL1.
Title: PSD-93 mediates the crosstalk between neuron and microglia and facilitates acute ischemic stroke injury by binding to CX3CL1.
PSD-93 Interacts with SynGAP and Promotes SynGAP Ubiquitination and Ischemic Brain Injury in Mice.
Title: PSD-93 Interacts with SynGAP and Promotes SynGAP Ubiquitination and Ischemic Brain Injury in Mice.
A DLG2 deficiency in mice leads to reduced sociability and increased repetitive behavior accompanied by aberrant synaptic transmission in the dorsal striatum.
Title: A DLG2 deficiency in mice leads to reduced sociability and increased repetitive behavior accompanied by aberrant synaptic transmission in the dorsal striatum.
PIP3-Phldb2 is crucial for LTP regulating synaptic NMDA and AMPA receptor density and PSD95 turnover.
Title: PIP(3)-Phldb2 is crucial for LTP regulating synaptic NMDA and AMPA receptor density and PSD95 turnover.
PSD-93 is identified as a target gene of miR-152-3p.
Title: MicroRNA-152-3p protects neurons from oxygen-glucose-deprivation/reoxygenation-induced injury through upregulation of Nrf2/ARE antioxidant signaling by targeting PSD-93.
Study describe a novel splice variant of Dlg2 gene termed Dlg2eta and define the differential expression pattern of DLG2 isoforms in IFNbeta-producing plasmacytoid dendritic cells (pDCs). The presence of DLG2eta protein in the CNS of Dlg2 mice might influence the phenotype of these mice and has to be taken into account in the interpretation of results regarding the functional role of DLG2 in neuronal postsynaptic membr...
Title: Identification of a novel Dlg2 isoform differentially expressed in IFNβ-producing plasmacytoid dendritic cells.
Study found robust hypersocial behavior in the dyadic interaction test in both PSD95(+/-) males and females. Additionally, male PSD95(+/-) mice exhibited higher levels of aggression and territoriality, while female PSD95(+/-) mice showed increased vocalization upon exposure to an anesthetized female mouse. Both male and female PSD95(+/-) mice revealed mild hypoactivity in the open field but no obvious motor deficit.
Title: Hypersocial behavior and biological redundancy in mice with reduced expression of PSD95 or PSD93.
This study demonstrated that in Chronic social defeat stress leads to changes PSD-93 in hippocampus of young mice.
Title: Chronic social defeat stress leads to changes of behaviour and memory-associated proteins of young mice.

Submit: New GeneRIF Correction See all GeneRIFs (23)

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Targeted (4) 1 citation

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

13.MHAa56f1.seq (e-PCR)
- UniSTS:123152

AU047030 (e-PCR)
- UniSTS:110910

G42651 (e-PCR)
- UniSTS:94551

D11S4187 (e-PCR)
- UniSTS:68955

D11S2286E (e-PCR)
- UniSTS:151416

D7Dcr38 (e-PCR), detects polymorphism
- UniSTS:507796

22.MMHAP25FRH7.seq (e-PCR)
- UniSTS:123562

46.MMHAP38FRH10.seq (e-PCR)
- UniSTS:124623

MHAa87b2.seq (e-PCR)
- UniSTS:125415

D7Mit301 (e-PCR), detects polymorphism
- UniSTS:116730

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables PDZ domain binding	ISO Inferred from Sequence Orthology more info
enables ionotropic glutamate receptor binding	IBA Inferred from Biological aspect of Ancestor more info
enables kinase binding	ISO Inferred from Sequence Orthology more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein kinase binding	IBA Inferred from Biological aspect of Ancestor more info
enables protein phosphatase binding	ISO Inferred from Sequence Orthology more info
enables protein-containing complex binding	ISO Inferred from Sequence Orthology more info
enables structural constituent of postsynaptic density	IDA Inferred from Direct Assay more info	PubMed
enables structural constituent of postsynaptic density	IEP Inferred from Expression Pattern more info	PubMed
enables structural constituent of postsynaptic density	IMP Inferred from Mutant Phenotype more info	PubMed

Process	Evidence Code	Pubs
involved_in anterograde axonal protein transport	IGI Inferred from Genetic Interaction more info	PubMed
involved_in cell-cell adhesion	IBA Inferred from Biological aspect of Ancestor more info
involved_in cellular response to potassium ion	IDA Inferred from Direct Assay more info	PubMed
involved_in chemical synaptic transmission	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within chemical synaptic transmission	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in clustering of voltage-gated potassium channels	IDA Inferred from Direct Assay more info	PubMed
involved_in clustering of voltage-gated potassium channels	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in establishment or maintenance of epithelial cell apical/basal polarity	IBA Inferred from Biological aspect of Ancestor more info
involved_in maintenance of postsynaptic density structure	IEA Inferred from Electronic Annotation more info
involved_in nervous system development	IBA Inferred from Biological aspect of Ancestor more info
involved_in neuronal ion channel clustering	ISO Inferred from Sequence Orthology more info
involved_in neurotransmitter receptor localization to postsynaptic specialization membrane	IDA Inferred from Direct Assay more info	PubMed
involved_in neurotransmitter receptor localization to postsynaptic specialization membrane	IEP Inferred from Expression Pattern more info	PubMed
involved_in neurotransmitter receptor localization to postsynaptic specialization membrane	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in protein localization to synapse	IBA Inferred from Biological aspect of Ancestor more info
involved_in receptor clustering	IBA Inferred from Biological aspect of Ancestor more info
involved_in receptor clustering	ISO Inferred from Sequence Orthology more info
involved_in receptor localization to synapse	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of postsynaptic membrane neurotransmitter receptor levels	IBA Inferred from Biological aspect of Ancestor more info
involved_in retrograde axonal protein transport	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within sensory perception of pain	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in axon cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in axon initial segment	IDA Inferred from Direct Assay more info	PubMed
is_active_in axon initial segment	IMP Inferred from Mutant Phenotype more info	PubMed
is_active_in basolateral plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in cell junction	IDA Inferred from Direct Assay more info	PubMed
located_in dendrite	ISO Inferred from Sequence Orthology more info
is_active_in glutamatergic synapse	IDA Inferred from Direct Assay more info	PubMed
is_active_in glutamatergic synapse	IEP Inferred from Expression Pattern more info	PubMed
is_active_in glutamatergic synapse	IMP Inferred from Mutant Phenotype more info	PubMed
is_active_in glutamatergic synapse	ISO Inferred from Sequence Orthology more info
located_in juxtaparanode region of axon	IDA Inferred from Direct Assay more info	PubMed
located_in juxtaparanode region of axon	ISO Inferred from Sequence Orthology more info
located_in membrane	ISO Inferred from Sequence Orthology more info
is_active_in neuromuscular junction	IBA Inferred from Biological aspect of Ancestor more info
located_in neuromuscular junction	IEA Inferred from Electronic Annotation more info
is_active_in neuron projection	IBA Inferred from Biological aspect of Ancestor more info
located_in neuronal cell body	ISO Inferred from Sequence Orthology more info
located_in perikaryon	IEA Inferred from Electronic Annotation more info
located_in postsynaptic density	IDA Inferred from Direct Assay more info	PubMed
is_active_in postsynaptic density membrane	IBA Inferred from Biological aspect of Ancestor more info
is_active_in postsynaptic density membrane	ISO Inferred from Sequence Orthology more info
located_in postsynaptic membrane	IDA Inferred from Direct Assay more info	PubMed
located_in synaptic vesicle membrane	IDA Inferred from Direct Assay more info	PubMed
part_of voltage-gated potassium channel complex	ISO Inferred from Sequence Orthology more info
part_of voltage-gated potassium channel complex	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: disks large homolog 2

Names: channel-associated protein of synapse-110; chapsyn-110; discs large MAGUK scaffold protein 2 eta; discs large MAGUK scaffold protein 2 gamma; discs, large homolog 2; postsynaptic density protein PSD-93

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001243046.1 → NP_001229975.1 disks large homolog 2 isoform 2

Status: VALIDATED

Description

Transcript Variant: This variant (2) differs in the 5' UTR and has multiple differences in the coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (2) has a distinct N-terminus and is shorter, compared to isoform 1.

Source sequence(s)

AC141890, AC158144, AK030221

Consensus CDS

CCDS57562.1

UniProtKB/TrEMBL

D3YWU0

Related

ENSMUSP00000095910.3, ENSMUST00000098308.4

Conserved Domains (4) summary

smart00072
Location:301 → 468

GuKc; Guanylate kinase homologues

cd00992
Location:16 → 94

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:290 → 468

Guanylate_kin; Guanylate kinase

cl17036
Location:131 → 204

SH3; Src Homology 3 domain superfamily
NM_001243047.1 → NP_001229976.1 disks large homolog 2 isoform 3

See identical proteins and their annotated locations for NP_001229976.1

Status: VALIDATED

Description

Transcript Variant: This variant (3) differs in the 5' UTR and uses a downstream, in-frame start codon, compared to variant 1. The encoded isoform (3) has a shorter N-terminus, compared to isoform 1.

Source sequence(s)

AC141890, AC158144, AK039754, CB520190

UniProtKB/Swiss-Prot

Q91XM9

Conserved Domains (2) summary

pfam00625
Location:143 → 321

Guanylate_kin; Guanylate kinase

cl17036
Location:16 → 89

SH3; Src Homology 3 domain superfamily
NM_011807.3 → NP_035937.2 disks large homolog 2 isoform 1

See identical proteins and their annotated locations for NP_035937.2

Status: VALIDATED

Description

Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).

Source sequence(s)

AC109506, AC118621, AC119218, AC121261, AC127299, AC141890, AC158144, AC161490

Consensus CDS

CCDS40021.1

UniProtKB/Swiss-Prot

F8VQM7, Q8BXK7, Q8BYG5, Q91XM9

UniProtKB/TrEMBL

E9Q2L2

Related

ENSMUSP00000102814.3, ENSMUST00000107196.10

Conserved Domains (6) summary

cd12032
Location:534 → 607

SH3_DLG2; Src Homology 3 domain of Disks Large homolog 2

smart00072
Location:672 → 839

GuKc; Guanylate kinase homologues

cd00992
Location:419 → 497

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:661 → 839

Guanylate_kin; Guanylate kinase

pfam10600
Location:278 → 345

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:14 → 97

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000073.7 Reference GRCm39 C57BL/6J

Range

90125399..92098454

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_036153031.1 → XP_036008924.1 disks large homolog 2 isoform X8

UniProtKB/TrEMBL

A0A338P6J0

Conserved Domains (6) summary

cd12032
Location:624 → 697

SH3_DLG2; Src Homology 3 domain of Disks Large homolog 2

cd00992
Location:509 → 587

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:783 → 961

Guanylate_kin; Guanylate kinase

pfam09058
Location:2 → 62

L27_1

pfam10600
Location:420 → 483

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:157 → 239

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
XM_006507776.5 → XP_006507839.1 disks large homolog 2 isoform X7

UniProtKB/TrEMBL

A0A338P6J0

Conserved Domains (6) summary

cd12032
Location:625 → 698

SH3_DLG2; Src Homology 3 domain of Disks Large homolog 2

cd00992
Location:510 → 588

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:784 → 962

Guanylate_kin; Guanylate kinase

pfam09058
Location:4 → 63

L27_1

pfam10600
Location:421 → 484

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:158 → 240

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
XM_006507769.5 → XP_006507832.1 disks large homolog 2 isoform X2

See identical proteins and their annotated locations for XP_006507832.1

UniProtKB/TrEMBL

A0A338P6J0

Conserved Domains (6) summary

cd12032
Location:676 → 749

SH3_DLG2; Src Homology 3 domain of Disks Large homolog 2

cd00992
Location:561 → 639

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:835 → 1013

Guanylate_kin; Guanylate kinase

pfam09058
Location:2 → 62

L27_1

pfam10600
Location:420 → 487

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:157 → 239

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
XM_006507767.5 → XP_006507830.1 disks large homolog 2 isoform X1

UniProtKB/TrEMBL

A0A338P6J0

Conserved Domains (6) summary

cd12032
Location:677 → 750

SH3_DLG2; Src Homology 3 domain of Disks Large homolog 2

cd00992
Location:562 → 640

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:836 → 1014

Guanylate_kin; Guanylate kinase

pfam09058
Location:4 → 63

L27_1

pfam10600
Location:421 → 488

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:158 → 240

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
XM_006507771.5 → XP_006507834.1 disks large homolog 2 isoform X4

UniProtKB/TrEMBL

A0A338P6J0

Conserved Domains (6) summary

cd12032
Location:677 → 750

SH3_DLG2; Src Homology 3 domain of Disks Large homolog 2

cd00992
Location:562 → 640

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:822 → 1000

Guanylate_kin; Guanylate kinase

pfam09058
Location:4 → 63

L27_1

pfam10600
Location:421 → 488

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:158 → 240

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
XM_036153032.1 → XP_036008925.1 disks large homolog 2 isoform X9

UniProtKB/TrEMBL

A0A338P6J0

Conserved Domains (6) summary

cd12032
Location:625 → 698

SH3_DLG2; Src Homology 3 domain of Disks Large homolog 2

cd00992
Location:510 → 588

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:766 → 944

Guanylate_kin; Guanylate kinase

pfam09058
Location:4 → 63

L27_1

pfam10600
Location:421 → 484

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:158 → 240

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
XM_006507777.5 → XP_006507840.1 disks large homolog 2 isoform X10

UniProtKB/TrEMBL

A0A338P6J0

Conserved Domains (6) summary

cd12032
Location:625 → 698

SH3_DLG2; Src Homology 3 domain of Disks Large homolog 2

cd00992
Location:510 → 588

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:752 → 930

Guanylate_kin; Guanylate kinase

pfam09058
Location:4 → 63

L27_1

pfam10600
Location:421 → 484

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:158 → 240

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
XM_006507770.5 → XP_006507833.1 disks large homolog 2 isoform X3

UniProtKB/TrEMBL

A0A338P6J0

Conserved Domains (6) summary

cd12032
Location:676 → 749

SH3_DLG2; Src Homology 3 domain of Disks Large homolog 2

cd00992
Location:561 → 639

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:835 → 1013

Guanylate_kin; Guanylate kinase

pfam09058
Location:4 → 63

L27_1

pfam10600
Location:420 → 487

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:158 → 239

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
XM_006507772.5 → XP_006507835.1 disks large homolog 2 isoform X5

UniProtKB/TrEMBL

A0A338P6J0

Conserved Domains (6) summary

cd12032
Location:677 → 750

SH3_DLG2; Src Homology 3 domain of Disks Large homolog 2

cd00992
Location:562 → 640

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:818 → 996

Guanylate_kin; Guanylate kinase

pfam09058
Location:4 → 63

L27_1

pfam10600
Location:421 → 488

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:158 → 240

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
XM_006507773.5 → XP_006507836.1 disks large homolog 2 isoform X6

UniProtKB/TrEMBL

A0A338P6J0

Related

ENSMUSP00000155862.3, ENSMUST00000231777.3

Conserved Domains (6) summary

cd12032
Location:677 → 750

SH3_DLG2; Src Homology 3 domain of Disks Large homolog 2

cd00992
Location:562 → 640

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:804 → 982

Guanylate_kin; Guanylate kinase

pfam09058
Location:4 → 63

L27_1

pfam10600
Location:421 → 488

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:158 → 240

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
XM_006507779.4 → XP_006507842.1 disks large homolog 2 isoform X12

UniProtKB/TrEMBL

E9Q2L2

Conserved Domains (5) summary

cd12032
Location:555 → 628

SH3_DLG2; Src Homology 3 domain of Disks Large homolog 2

cd00992
Location:440 → 518

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:714 → 892

Guanylate_kin; Guanylate kinase

pfam10600
Location:299 → 366

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:36 → 118

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
XM_036153033.1 → XP_036008926.1 disks large homolog 2 isoform X15

UniProtKB/TrEMBL

E9Q2L2

Conserved Domains (5) summary

cd12032
Location:554 → 627

SH3_DLG2; Src Homology 3 domain of Disks Large homolog 2

cd00992
Location:439 → 517

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:713 → 891

Guanylate_kin; Guanylate kinase

pfam10600
Location:298 → 365

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:36 → 117

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
XM_036153043.1 → XP_036008936.1 disks large homolog 2 isoform X32

UniProtKB/TrEMBL

E9Q2L2

Conserved Domains (5) summary

cd12032
Location:482 → 555

SH3_DLG2; Src Homology 3 domain of Disks Large homolog 2

cd00992
Location:367 → 445

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:641 → 819

Guanylate_kin; Guanylate kinase

pfam10600
Location:278 → 341

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:14 → 97

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
XM_006507784.5 → XP_006507847.1 disks large homolog 2 isoform X20

UniProtKB/TrEMBL

E9Q2L2

Conserved Domains (5) summary

cd12032
Location:533 → 606

SH3_DLG2; Src Homology 3 domain of Disks Large homolog 2

cd00992
Location:418 → 496

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:692 → 870

Guanylate_kin; Guanylate kinase

pfam10600
Location:277 → 344

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:14 → 96

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
XM_006507783.5 → XP_006507846.1 disks large homolog 2 isoform X19

UniProtKB/TrEMBL

E9Q2L2

Related

ENSMUSP00000073885.4, ENSMUST00000074273.10

Conserved Domains (5) summary

cd12032
Location:534 → 607

SH3_DLG2; Src Homology 3 domain of Disks Large homolog 2

cd00992
Location:419 → 497

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:693 → 871

Guanylate_kin; Guanylate kinase

pfam10600
Location:278 → 345

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:14 → 97

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
XM_036153038.1 → XP_036008931.1 disks large homolog 2 isoform X24

UniProtKB/TrEMBL

E9Q2L2

Conserved Domains (5) summary

cd12032
Location:533 → 606

SH3_DLG2; Src Homology 3 domain of Disks Large homolog 2

cd00992
Location:418 → 496

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:674 → 852

Guanylate_kin; Guanylate kinase

pfam10600
Location:277 → 344

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:14 → 96

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
XM_036153041.1 → XP_036008934.1 disks large homolog 2 isoform X28

UniProtKB/TrEMBL

E9Q2L2

Conserved Domains (5) summary

cd12032
Location:533 → 606

SH3_DLG2; Src Homology 3 domain of Disks Large homolog 2

cd00992
Location:418 → 496

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:660 → 838

Guanylate_kin; Guanylate kinase

pfam10600
Location:277 → 344

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:14 → 96

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
XM_006507781.5 → XP_006507844.1 disks large homolog 2 isoform X14

UniProtKB/TrEMBL

E9Q2L2

Conserved Domains (5) summary

cd12032
Location:554 → 627

SH3_DLG2; Src Homology 3 domain of Disks Large homolog 2

cd00992
Location:439 → 517

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:713 → 891

Guanylate_kin; Guanylate kinase

pfam10600
Location:298 → 365

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:34 → 117

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
XM_036153035.1 → XP_036008928.1 disks large homolog 2 isoform X18

UniProtKB/TrEMBL

E9Q2L2

Conserved Domains (5) summary

cd12032
Location:554 → 627

SH3_DLG2; Src Homology 3 domain of Disks Large homolog 2

cd00992
Location:439 → 517

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:695 → 873

Guanylate_kin; Guanylate kinase

pfam10600
Location:298 → 365

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:34 → 117

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
XM_036153036.1 → XP_036008929.1 disks large homolog 2 isoform X21

UniProtKB/TrEMBL

E9Q2L2

Conserved Domains (5) summary

cd12032
Location:554 → 627

SH3_DLG2; Src Homology 3 domain of Disks Large homolog 2

cd00992
Location:439 → 517

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:681 → 859

Guanylate_kin; Guanylate kinase

pfam10600
Location:298 → 365

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:34 → 117

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
XM_036153040.1 → XP_036008933.1 disks large homolog 2 isoform X27

UniProtKB/TrEMBL

E9Q2L2

Conserved Domains (5) summary

cd12032
Location:502 → 575

SH3_DLG2; Src Homology 3 domain of Disks Large homolog 2

cd00992
Location:387 → 465

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:661 → 839

Guanylate_kin; Guanylate kinase

pfam10600
Location:298 → 361

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:34 → 117

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
XM_006507782.5 → XP_006507845.1 disks large homolog 2 isoform X16

UniProtKB/TrEMBL

E9Q2L2

Conserved Domains (5) summary

cd12032
Location:553 → 626

SH3_DLG2; Src Homology 3 domain of Disks Large homolog 2

cd00992
Location:438 → 516

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:712 → 890

Guanylate_kin; Guanylate kinase

pfam10600
Location:297 → 364

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:34 → 116

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
XM_030242541.2 → XP_030098401.1 disks large homolog 2 isoform X22

UniProtKB/TrEMBL

E9Q2L2

Conserved Domains (5) summary

cd12032
Location:553 → 626

SH3_DLG2; Src Homology 3 domain of Disks Large homolog 2

cd00992
Location:438 → 516

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:680 → 858

Guanylate_kin; Guanylate kinase

pfam10600
Location:297 → 364

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:34 → 116

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
XM_006507786.4 → XP_006507849.1 disks large homolog 2 isoform X30

UniProtKB/TrEMBL

E9Q2L2

Conserved Domains (5) summary

cd12032
Location:492 → 565

SH3_DLG2; Src Homology 3 domain of Disks Large homolog 2

cd00992
Location:377 → 455

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:651 → 829

Guanylate_kin; Guanylate kinase

pfam10600
Location:236 → 303

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:25 → 55

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
XM_036153045.1 → XP_036008938.1 disks large homolog 2 isoform X34

UniProtKB/TrEMBL

E9Q2L2

Conserved Domains (5) summary

cd12032
Location:492 → 565

SH3_DLG2; Src Homology 3 domain of Disks Large homolog 2

cd00992
Location:377 → 455

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:619 → 797

Guanylate_kin; Guanylate kinase

pfam10600
Location:236 → 303

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:24 → 55

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
XM_030242543.2 → XP_030098403.1 disks large homolog 2 isoform X36

UniProtKB/TrEMBL

D3YUZ8

Conserved Domains (5) summary

cd12032
Location:440 → 513

SH3_DLG2; Src Homology 3 domain of Disks Large homolog 2

cd00992
Location:325 → 403

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:599 → 777

Guanylate_kin; Guanylate kinase

pfam10600
Location:236 → 299

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:25 → 55

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
XM_036153037.1 → XP_036008930.1 disks large homolog 2 isoform X23

UniProtKB/TrEMBL

A0A571BEK3

Conserved Domains (5) summary

cd12032
Location:517 → 590

SH3_DLG2; Src Homology 3 domain of Disks Large homolog 2

cd00992
Location:402 → 480

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:676 → 854

Guanylate_kin; Guanylate kinase

pfam10600
Location:313 → 376

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:45 → 132

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
XM_036153039.1 → XP_036008932.1 disks large homolog 2 isoform X26

UniProtKB/TrEMBL

A0A571BEK3

Conserved Domains (5) summary

cd12032
Location:517 → 590

SH3_DLG2; Src Homology 3 domain of Disks Large homolog 2

cd00992
Location:402 → 480

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:662 → 840

Guanylate_kin; Guanylate kinase

pfam10600
Location:313 → 376

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:45 → 132

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
XM_036153042.1 → XP_036008935.1 disks large homolog 2 isoform X31

UniProtKB/TrEMBL

A0A571BEK3

Conserved Domains (5) summary

cd12032
Location:517 → 590

SH3_DLG2; Src Homology 3 domain of Disks Large homolog 2

cd00992
Location:402 → 480

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:644 → 822

Guanylate_kin; Guanylate kinase

pfam10600
Location:313 → 376

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:45 → 132

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
XM_006507778.4 → XP_006507841.1 disks large homolog 2 isoform X11

UniProtKB/TrEMBL

A0A571BEK3, A0A571BEZ4

Related

ENSMUSP00000158695.2, ENSMUST00000238467.2

Conserved Domains (5) summary

cd12032
Location:569 → 642

SH3_DLG2; Src Homology 3 domain of Disks Large homolog 2

cd00992
Location:454 → 532

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:728 → 906

Guanylate_kin; Guanylate kinase

pfam10600
Location:313 → 380

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:45 → 132

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
XM_006507780.4 → XP_006507843.1 disks large homolog 2 isoform X13

UniProtKB/TrEMBL

A0A571BEK3

Conserved Domains (5) summary

cd12032
Location:569 → 642

SH3_DLG2; Src Homology 3 domain of Disks Large homolog 2

cd00992
Location:454 → 532

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:714 → 892

Guanylate_kin; Guanylate kinase

pfam10600
Location:313 → 380

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:45 → 132

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
XM_036153034.1 → XP_036008927.1 disks large homolog 2 isoform X17

UniProtKB/TrEMBL

A0A571BEK3

Related

ENSMUSP00000158731.2, ENSMUST00000238619.2

Conserved Domains (5) summary

cd12032
Location:569 → 642

SH3_DLG2; Src Homology 3 domain of Disks Large homolog 2

cd00992
Location:454 → 532

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:696 → 874

Guanylate_kin; Guanylate kinase

pfam10600
Location:313 → 380

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:45 → 132

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
XM_006507785.1 → XP_006507848.1 disks large homolog 2 isoform X25

UniProtKB/TrEMBL

E9Q2L2

Conserved Domains (5) summary

cd12032
Location:507 → 580

SH3_DLG2; Src Homology 3 domain of Disks Large homolog 2

cd00992
Location:392 → 470

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:666 → 844

Guanylate_kin; Guanylate kinase

pfam10600
Location:251 → 318

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:42 → 70

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
XM_030242542.1 → XP_030098402.1 disks large homolog 2 isoform X29

UniProtKB/TrEMBL

A0A2L2P590, E9Q2L2

Conserved Domains (5) summary

cd12032
Location:507 → 580

SH3_DLG2; Src Homology 3 domain of Disks Large homolog 2

cd00992
Location:392 → 470

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:652 → 830

Guanylate_kin; Guanylate kinase

pfam10600
Location:251 → 318

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:42 → 70

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
XM_036153044.1 → XP_036008937.1 disks large homolog 2 isoform X33

UniProtKB/TrEMBL

D3YUZ8

Conserved Domains (5) summary

cd12032
Location:507 → 580

SH3_DLG2; Src Homology 3 domain of Disks Large homolog 2

cd00992
Location:392 → 470

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:634 → 812

Guanylate_kin; Guanylate kinase

pfam10600
Location:251 → 318

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:42 → 70

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
XM_036153047.1 → XP_036008940.1 disks large homolog 2 isoform X37

UniProtKB/TrEMBL

D3YUZ8

Related

ENSMUSP00000102811.2, ENSMUST00000107193.8

Conserved Domains (5) summary

cd12032
Location:455 → 528

SH3_DLG2; Src Homology 3 domain of Disks Large homolog 2

cd00992
Location:340 → 418

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:582 → 760

Guanylate_kin; Guanylate kinase

pfam10600
Location:251 → 314

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:42 → 70

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
XM_036153046.1 → XP_036008939.1 disks large homolog 2 isoform X35

UniProtKB/TrEMBL

D3YUZ8

Conserved Domains (5) summary

cd12032
Location:455 → 528

SH3_DLG2; Src Homology 3 domain of Disks Large homolog 2

cd00992
Location:340 → 418

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:614 → 792

Guanylate_kin; Guanylate kinase

pfam10600
Location:251 → 314

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:42 → 70

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
XM_006507789.5 → XP_006507852.1 disks large homolog 2 isoform X38

See identical proteins and their annotated locations for XP_006507852.1

Conserved Domains (2) summary

pfam00625
Location:175 → 353

Guanylate_kin; Guanylate kinase

cl17036
Location:16 → 89

SH3; Src Homology 3 domain superfamily
XM_036153050.1 → XP_036008943.1 disks large homolog 2 isoform X40

Conserved Domains (2) summary

pfam00625
Location:157 → 335

Guanylate_kin; Guanylate kinase

cl17036
Location:16 → 89

SH3; Src Homology 3 domain superfamily
XM_006507788.5 → XP_006507851.1 disks large homolog 2 isoform X38

See identical proteins and their annotated locations for XP_006507851.1

Conserved Domains (2) summary

pfam00625
Location:175 → 353

Guanylate_kin; Guanylate kinase

cl17036
Location:16 → 89

SH3; Src Homology 3 domain superfamily
XM_036153049.1 → XP_036008942.1 disks large homolog 2 isoform X40

Conserved Domains (2) summary

pfam00625
Location:157 → 335

Guanylate_kin; Guanylate kinase

cl17036
Location:16 → 89

SH3; Src Homology 3 domain superfamily
XM_006507790.5 → XP_006507853.1 disks large homolog 2 isoform X41

See identical proteins and their annotated locations for XP_006507853.1

Conserved Domains (2) summary

pfam00625
Location:143 → 321

Guanylate_kin; Guanylate kinase

cl17036
Location:16 → 89

SH3; Src Homology 3 domain superfamily
XM_006507787.5 → XP_006507850.1 disks large homolog 2 isoform X38

See identical proteins and their annotated locations for XP_006507850.1

Conserved Domains (2) summary

pfam00625
Location:175 → 353

Guanylate_kin; Guanylate kinase

cl17036
Location:16 → 89

SH3; Src Homology 3 domain superfamily
XM_036153051.1 → XP_036008944.1 disks large homolog 2 isoform X40

Conserved Domains (2) summary

pfam00625
Location:157 → 335

Guanylate_kin; Guanylate kinase

cl17036
Location:16 → 89

SH3; Src Homology 3 domain superfamily
XM_036153048.1 → XP_036008941.1 disks large homolog 2 isoform X39

UniProtKB/TrEMBL

A0A2L2P595

Conserved Domains (2) summary

pfam00625
Location:161 → 339

Guanylate_kin; Guanylate kinase

cl17036
Location:16 → 89

SH3; Src Homology 3 domain superfamily