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    Rtp3 receptor transporter protein 3 [ Mus musculus (house mouse) ]

    Gene ID: 235636, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Rtp3provided by MGI
    Official Full Name
    receptor transporter protein 3provided by MGI
    Primary source
    MGI:MGI:2446841
    See related
    Ensembl:ENSMUSG00000066319 AllianceGenome:MGI:2446841
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Tmem7
    Summary
    Predicted to enable olfactory receptor binding activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception of bitter taste; protein insertion into membrane; and protein targeting to membrane. Predicted to be located in membrane. Predicted to be active in cytoplasm. Orthologous to human RTP3 (receptor transporter protein 3). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in liver E18 (RPKM 10.9), liver E14.5 (RPKM 9.7) and 10 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Rtp3 in Genome Data Viewer
    Location:
    9 F2; 9 60.79 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (110814003..110818781, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (110984935..110990265, complement)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene CRISPRi-validated Tdgf1 proximal enhancer Neighboring gene cripto, EGF-CFC family member Neighboring gene leucine rich repeat containing 2 Neighboring gene predicted gene 10030 Neighboring gene lactotransferrin Neighboring gene C-C motif chemokine receptor-like 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Comparative human/murine sequence analysis of the common eliminated region 1 from human 3p21.3. Kiss H, et al. Mamm Genome, 2002 Nov. PMID 12461651
    2. RTP family members induce functional expression of mammalian odorant receptors. Saito H, et al. Cell, 2004 Nov 24. PMID 15550249
    3. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article
    4. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Homology

    Clone Names

    • MGC118000

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables olfactory receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in detection of chemical stimulus involved in sensory perception of bitter taste IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in detection of chemical stimulus involved in sensory perception of bitter taste ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in protein insertion into membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein targeting to membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein targeting to membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    receptor-transporting protein 3
    Names
    transmembrane protein 7

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_153100.2 → NP_694740.2  receptor-transporting protein 3

      See identical proteins and their annotated locations for NP_694740.2

      Status: VALIDATED

      Source sequence(s)
      AC118727
      Consensus CDS
      CCDS81087.1
      UniProtKB/Swiss-Prot
      E9QP29, Q2KHT1, Q5QGU6, Q8VDC2
      UniProtKB/TrEMBL
      B2RWS3
      Related
      ENSMUSP00000143305.2, ENSMUST00000199891.2
      Conserved Domains (2) summary
      pfam05109
      Location:214 → 393
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam13695
      Location:52 → 164
      zf-3CxxC; Zinc-binding domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      110814003..110818781 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036154920.1 → XP_036010813.1  receptor-transporting protein 3 isoform X1

      UniProtKB/TrEMBL
      B2RWS3
      Conserved Domains (2) summary
      PHA03247
      Location:171 → 453
      PHA03247; large tegument protein UL36; Provisional
      pfam13695
      Location:52 → 164
      zf-3CxxC; Zinc-binding domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5QGU6.2 GenPept UniProtKB/Swiss-Prot:Q5QGU6

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
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