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    Scara3 scavenger receptor class A, member 3 [ Mus musculus (house mouse) ]

    Gene ID: 219151, updated on 2-Nov-2024

    Summary

    Official Symbol
    Scara3provided by MGI
    Official Full Name
    scavenger receptor class A, member 3provided by MGI
    Primary source
    MGI:MGI:2444418
    See related
    Ensembl:ENSMUSG00000034463 AllianceGenome:MGI:2444418
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    CSR; APC7; CSR1; MSLR1; MSRL1; C130058N24Rik
    Summary
    Predicted to be an extracellular matrix structural constituent conferring tensile strength. Predicted to be involved in extracellular matrix organization. Predicted to be located in endoplasmic reticulum. Predicted to be part of collagen trimer. Predicted to be active in collagen-containing extracellular matrix and extracellular space. Is expressed in several structures, including brain; embryo mesenchyme; jaw skeleton; long bone; and sensory organ. Orthologous to human SCARA3 (scavenger receptor class A member 3). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in limb E14.5 (RPKM 18.5), mammary gland adult (RPKM 16.6) and 22 other tissues See more
    Orthologs
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    Genomic context

    See Scara3 in Genome Data Viewer
    Location:
    14 D1; 14 34.36 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (66156844..66191427, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (65919394..65953978, complement)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E5449 Neighboring gene coiled-coil domain containing 25 Neighboring gene CapStarr-seq enhancer MGSCv37_chr14:66503658-66503811 Neighboring gene predicted gene, 41181 Neighboring gene predicted gene, 41182 Neighboring gene predicted gene, 19222 Neighboring gene clusterin

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables extracellular matrix structural constituent conferring tensile strength IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in extracellular matrix organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
     
    part_of collagen trimer IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in collagen-containing extracellular matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    scavenger receptor class A member 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_172604.3NP_766192.1  scavenger receptor class A member 3

      See identical proteins and their annotated locations for NP_766192.1

      Status: PROVISIONAL

      Source sequence(s)
      AC125058, AC126444
      Consensus CDS
      CCDS49524.1
      UniProtKB/Swiss-Prot
      Q8C6N1, Q8C850
      Related
      ENSMUSP00000046525.4, ENSMUST00000042046.5
      Conserved Domains (1) summary
      pfam01391
      Location:475584
      Collagen; Collagen triple helix repeat (20 copies)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      66156844..66191427 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036158569.1XP_036014462.1  scavenger receptor class A member 3 isoform X1