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    Szrd1 SUZ RNA binding domain containing 1 [ Mus musculus (house mouse) ]

    Gene ID: 213491, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Szrd1provided by MGI
    Official Full Name
    SUZ RNA binding domain containing 1provided by MGI
    Primary source
    MGI:MGI:1098672
    See related
    Ensembl:ENSMUSG00000040842 AllianceGenome:MGI:1098672
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    D4Ertd22e; 1110022I03
    Summary
    Orthologous to human SZRD1 (SUZ RNA binding domain containing 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in adrenal adult (RPKM 23.3), duodenum adult (RPKM 22.4) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Szrd1 in Genome Data Viewer
    Location:
    4 D3; 4 73.38 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (140840326..140867110, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (141112978..141139799, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene ribosomal protein S2 pseudogene Neighboring gene spermatogenesis associated 21 Neighboring gene STARR-seq mESC enhancer starr_11890 Neighboring gene STARR-positive B cell enhancer ABC_E3533 Neighboring gene STARR-positive B cell enhancer ABC_E3534 Neighboring gene F-box protein 42 Neighboring gene STARR-seq mESC enhancer starr_11892 Neighboring gene STARR-positive B cell enhancer ABC_E10273 Neighboring gene STARR-positive B cell enhancer ABC_E3535 Neighboring gene STARR-positive B cell enhancer ABC_E6249 Neighboring gene ciliogenesis and planar polarity effector 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Tagging genes with cassette-exchange sites. Cobellis G, et al. Nucleic Acids Res, 2005 Mar 1. PMID 15741177, Free PMC Article
    2. Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette. Taniwaki T, et al. Dev Growth Differ, 2005 Apr. PMID 15840001
    3. Exchangeable gene trap using the Cre/mutated lox system. Araki K, et al. Cell Mol Biol (Noisy-le-grand), 1999 Jul. PMID 10512203
    4. Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Piao Y, et al. Genome Res, 2001 Sep. PMID 11544199, Free PMC Article
    5. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    SUZ RNA-binding domain-containing; SUZ domain-containing protein 1
    Names
    UPF0485 protein C1orf144 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025608.3 → NP_001020779.1  SUZ RNA-binding domain-containing isoform 1

      See identical proteins and their annotated locations for NP_001020779.1

      Status: VALIDATED

      Source sequence(s)
      AL645625
      Consensus CDS
      CCDS18864.1
      UniProtKB/Swiss-Prot
      Q3TB72, Q6NXN1, Q8BT36
      UniProtKB/TrEMBL
      A2AA85
      Related
      ENSMUSP00000099545.4, ENSMUST00000102487.4
      Conserved Domains (2) summary
      pfam12752
      Location:56 → 107
      SUZ; SUZ domain
      pfam12901
      Location:119 → 151
      SUZ-C; SUZ-C motif

    2. NM_001277195.2 → NP_001264124.1  SUZ RNA-binding domain-containing isoform 3

      See identical proteins and their annotated locations for NP_001264124.1

      Status: VALIDATED

      Source sequence(s)
      AL645625
      UniProtKB/TrEMBL
      A2AA85
      Related
      ENSMUSP00000115949.2, ENSMUST00000148204.8
      Conserved Domains (2) summary
      pfam12752
      Location:55 → 106
      SUZ; SUZ domain
      pfam12901
      Location:118 → 150
      SUZ-C; SUZ-C motif

    RNA

    1. NR_102343.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL645625
      Related
      ENSMUST00000094549.11

    2. NR_102344.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL645625
      Related
      ENSMUST00000039939.7

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      140840326..140867110 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030253383.1 → XP_030109243.1  SUZ domain-containing protein 1 isoform X5

      Conserved Domains (1) summary
      pfam12752
      Location:55 → 106
      SUZ; SUZ domain

    2. XM_006538700.3 → XP_006538763.1  SUZ domain-containing protein 1 isoform X4

      UniProtKB/TrEMBL
      A2AA85
      Conserved Domains (2) summary
      pfam12752
      Location:48 → 99
      SUZ; SUZ domain
      pfam12901
      Location:127 → 143
      SUZ-C; SUZ-C motif

    3. XM_006538699.5 → XP_006538762.1  SUZ domain-containing protein 1 isoform X3

      UniProtKB/TrEMBL
      A2AA85
      Conserved Domains (2) summary
      pfam12752
      Location:49 → 100
      SUZ; SUZ domain
      pfam12901
      Location:128 → 144
      SUZ-C; SUZ-C motif

    4. XM_006538695.5 → XP_006538758.1  SUZ domain-containing protein 1 isoform X2

      UniProtKB/TrEMBL
      A2AA85
      Conserved Domains (2) summary
      pfam12752
      Location:63 → 114
      SUZ; SUZ domain
      pfam12901
      Location:142 → 158
      SUZ-C; SUZ-C motif

    5. XM_006538694.5 → XP_006538757.1  SUZ domain-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      A2AA85
      Conserved Domains (2) summary
      pfam12752
      Location:64 → 115
      SUZ; SUZ domain
      pfam12901
      Location:143 → 159
      SUZ-C; SUZ-C motif

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_174996.2: Suppressed sequence

      Description
      NM_174996.2: This RefSeq was permanently suppressed because currently there is support for the transcript but not for the protein.
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6NXN1.1 GenPept UniProtKB/Swiss-Prot:Q6NXN1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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