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    ZNF266 zinc finger protein 266 [ Homo sapiens (human) ]

    Gene ID: 10781, updated on 2-Nov-2024

    Summary

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    Official Symbol
    ZNF266provided by HGNC
    Official Full Name
    zinc finger protein 266provided by HGNC
    Primary source
    HGNC:HGNC:13059
    See related
    Ensembl:ENSG00000174652 MIM:604751; AllianceGenome:HGNC:13059
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    HZF1
    Summary
    This gene encodes a protein containing many tandem zinc-finger motifs. Zinc fingers are protein or nucleic acid-binding domains, and may be involved in a variety of functions, including regulation of transcription. This gene is located in a cluster of similar genes encoding zinc finger proteins on chromosome 19. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Sep 2012]
    Expression
    Ubiquitous expression in spleen (RPKM 14.7), lymph node (RPKM 12.7) and 25 other tissues See more
    Orthologs
    all
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    Genomic context

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    See ZNF266 in Genome Data Viewer
    Location:
    19p13.2
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (9412429..9435573, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (9538632..9561760, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (9523105..9546249, complement)

    Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene ZNF559-ZNF177 readthrough Neighboring gene zinc finger protein 177 Neighboring gene uncharacterized LOC112268250 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13929 Neighboring gene uncharacterized LOC105372269 Neighboring gene zinc finger protein 560 Neighboring gene uncharacterized LOC105372268 Neighboring gene actin beta pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Analysis of SNPs with an effect on gene expression identifies UBE2L3 and BCL3 as potential new risk genes for Crohn's disease. Fransen K, et al. Hum Mol Genet, 2010 Sep 1. PMID 20601676
    2. Isolation of cDNA clones for 42 different Krüppel-related zinc finger proteins expressed in the human monoblast cell line U-937. Abrink M, et al. DNA Cell Biol, 1995 Feb. PMID 7865130
    3. Sticky fingers: zinc-fingers as protein-recognition motifs. Gamsjaeger R, et al. Trends Biochem Sci, 2007 Feb. PMID 17210253
    4. A directed protein interaction network for investigating intracellular signal transduction. Vinayagam A, et al. Sci Signal, 2011 Sep 6. PMID 21900206
    5. Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations. Fragoza R, et al. Nat Commun, 2019 Sep 12. PMID 31515488, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Observational study and meta-analysis of gene-disease association. (HuGE Navigator)
      Title: Analysis of SNPs with an effect on gene expression identifies UBE2L3 and BCL3 as potential new risk genes for Crohn's disease.
    Submit: New GeneRIF Correction

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 266
    Names
    zinc finger protein 1
    zinc finger protein HZF1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001271314.2 → NP_001258243.1  zinc finger protein 266 isoform 1

      See identical proteins and their annotated locations for NP_001258243.1

      Status: REVIEWED

      Source sequence(s)
      AC011451, AL833503, CN484252, DA735170
      Consensus CDS
      CCDS12213.1
      UniProtKB/Swiss-Prot
      A0AV90, A4FU85, Q14584, Q6IQ07, Q6U8A5, Q8IVG3, Q8WVX1, Q96SX9
      Related
      ENSP00000467151.1, ENST00000588933.5
      Conserved Domains (4) summary
      COG5048
      Location:210 → 549
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:382 → 402
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:132 → 150
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02581
      Location:1 → 28
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

    2. NM_001370374.1 → NP_001357303.1  zinc finger protein 266 isoform 2

      Status: REVIEWED

      Source sequence(s)
      AC011451
      Consensus CDS
      CCDS92507.1
      UniProtKB/TrEMBL
      A0A3F2YPB8
      Related
      ENSP00000466714.2, ENST00000592904.7
      Conserved Domains (4) summary
      smart00349
      Location:39 → 95
      KRAB; krueppel associated box
      COG5048
      Location:277 → 616
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:449 → 469
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:199 → 217
      ZF_C2H2; C2H2 Zn finger [structural motif]

    3. NM_001370375.1 → NP_001357304.1  zinc finger protein 266 isoform 2

      Status: REVIEWED

      Source sequence(s)
      AC011451
      Consensus CDS
      CCDS92507.1
      UniProtKB/TrEMBL
      A0A3F2YPB8
      Conserved Domains (4) summary
      smart00349
      Location:39 → 95
      KRAB; krueppel associated box
      COG5048
      Location:277 → 616
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:449 → 469
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:199 → 217
      ZF_C2H2; C2H2 Zn finger [structural motif]

    4. NM_001370376.1 → NP_001357305.1  zinc finger protein 266 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AC011451
      Consensus CDS
      CCDS12213.1
      UniProtKB/Swiss-Prot
      A0AV90, A4FU85, Q14584, Q6IQ07, Q6U8A5, Q8IVG3, Q8WVX1, Q96SX9
      Conserved Domains (4) summary
      COG5048
      Location:210 → 549
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:382 → 402
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:132 → 150
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02581
      Location:1 → 28
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

    5. NM_001370377.1 → NP_001357306.1  zinc finger protein 266 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AC011451
      Consensus CDS
      CCDS12213.1
      UniProtKB/Swiss-Prot
      A0AV90, A4FU85, Q14584, Q6IQ07, Q6U8A5, Q8IVG3, Q8WVX1, Q96SX9
      Conserved Domains (4) summary
      COG5048
      Location:210 → 549
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:382 → 402
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:132 → 150
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02581
      Location:1 → 28
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

    6. NM_001370378.1 → NP_001357307.1  zinc finger protein 266 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AC011451
      Consensus CDS
      CCDS12213.1
      UniProtKB/Swiss-Prot
      A0AV90, A4FU85, Q14584, Q6IQ07, Q6U8A5, Q8IVG3, Q8WVX1, Q96SX9
      Related
      ENSP00000498589.1, ENST00000651268.1
      Conserved Domains (4) summary
      COG5048
      Location:210 → 549
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:382 → 402
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:132 → 150
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02581
      Location:1 → 28
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

    7. NM_001370379.1 → NP_001357308.1  zinc finger protein 266 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AC011451
      Consensus CDS
      CCDS12213.1
      UniProtKB/Swiss-Prot
      A0AV90, A4FU85, Q14584, Q6IQ07, Q6U8A5, Q8IVG3, Q8WVX1, Q96SX9
      Conserved Domains (4) summary
      COG5048
      Location:210 → 549
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:382 → 402
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:132 → 150
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02581
      Location:1 → 28
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

    8. NM_001370380.1 → NP_001357309.1  zinc finger protein 266 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AC011451
      Consensus CDS
      CCDS12213.1
      UniProtKB/Swiss-Prot
      A0AV90, A4FU85, Q14584, Q6IQ07, Q6U8A5, Q8IVG3, Q8WVX1, Q96SX9
      Related
      ENSP00000468491.1, ENST00000588221.5
      Conserved Domains (4) summary
      COG5048
      Location:210 → 549
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:382 → 402
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:132 → 150
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02581
      Location:1 → 28
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

    9. NM_001370381.1 → NP_001357310.1  zinc finger protein 266 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AC011451
      Consensus CDS
      CCDS12213.1
      UniProtKB/Swiss-Prot
      A0AV90, A4FU85, Q14584, Q6IQ07, Q6U8A5, Q8IVG3, Q8WVX1, Q96SX9
      Conserved Domains (4) summary
      COG5048
      Location:210 → 549
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:382 → 402
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:132 → 150
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02581
      Location:1 → 28
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

    10. NM_001370382.1 → NP_001357311.1  zinc finger protein 266 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AC011451
      Consensus CDS
      CCDS12213.1
      UniProtKB/Swiss-Prot
      A0AV90, A4FU85, Q14584, Q6IQ07, Q6U8A5, Q8IVG3, Q8WVX1, Q96SX9
      Conserved Domains (4) summary
      COG5048
      Location:210 → 549
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:382 → 402
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:132 → 150
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02581
      Location:1 → 28
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

    11. NM_001370383.1 → NP_001357312.1  zinc finger protein 266 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AC011451
      Consensus CDS
      CCDS12213.1
      UniProtKB/Swiss-Prot
      A0AV90, A4FU85, Q14584, Q6IQ07, Q6U8A5, Q8IVG3, Q8WVX1, Q96SX9
      Conserved Domains (4) summary
      COG5048
      Location:210 → 549
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:382 → 402
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:132 → 150
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02581
      Location:1 → 28
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

    12. NM_001370384.1 → NP_001357313.1  zinc finger protein 266 isoform 2

      Status: REVIEWED

      Source sequence(s)
      AC011451
      Consensus CDS
      CCDS92507.1
      UniProtKB/TrEMBL
      A0A3F2YPB8
      Conserved Domains (4) summary
      smart00349
      Location:39 → 95
      KRAB; krueppel associated box
      COG5048
      Location:277 → 616
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:449 → 469
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:199 → 217
      ZF_C2H2; C2H2 Zn finger [structural motif]

    13. NM_001370385.1 → NP_001357314.1  zinc finger protein 266 isoform 2

      Status: REVIEWED

      Source sequence(s)
      AC011451
      Consensus CDS
      CCDS92507.1
      UniProtKB/TrEMBL
      A0A3F2YPB8
      Conserved Domains (4) summary
      smart00349
      Location:39 → 95
      KRAB; krueppel associated box
      COG5048
      Location:277 → 616
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:449 → 469
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:199 → 217
      ZF_C2H2; C2H2 Zn finger [structural motif]

    14. NM_001370386.1 → NP_001357315.1  zinc finger protein 266 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AC011451
      Consensus CDS
      CCDS12213.1
      UniProtKB/Swiss-Prot
      A0AV90, A4FU85, Q14584, Q6IQ07, Q6U8A5, Q8IVG3, Q8WVX1, Q96SX9
      Conserved Domains (4) summary
      COG5048
      Location:210 → 549
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:382 → 402
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:132 → 150
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02581
      Location:1 → 28
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

    15. NM_001370387.1 → NP_001357316.1  zinc finger protein 266 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AC011451
      Consensus CDS
      CCDS12213.1
      UniProtKB/Swiss-Prot
      A0AV90, A4FU85, Q14584, Q6IQ07, Q6U8A5, Q8IVG3, Q8WVX1, Q96SX9
      Conserved Domains (4) summary
      COG5048
      Location:210 → 549
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:382 → 402
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:132 → 150
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02581
      Location:1 → 28
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

    16. NM_001370388.1 → NP_001357317.1  zinc finger protein 266 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AC011451
      Consensus CDS
      CCDS12213.1
      UniProtKB/Swiss-Prot
      A0AV90, A4FU85, Q14584, Q6IQ07, Q6U8A5, Q8IVG3, Q8WVX1, Q96SX9
      Related
      ENSP00000467403.1, ENST00000592292.5
      Conserved Domains (4) summary
      COG5048
      Location:210 → 549
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:382 → 402
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:132 → 150
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02581
      Location:1 → 28
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

    17. NM_001370389.1 → NP_001357318.1  zinc finger protein 266 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AC011451
      Consensus CDS
      CCDS12213.1
      UniProtKB/Swiss-Prot
      A0AV90, A4FU85, Q14584, Q6IQ07, Q6U8A5, Q8IVG3, Q8WVX1, Q96SX9
      Conserved Domains (4) summary
      COG5048
      Location:210 → 549
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:382 → 402
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:132 → 150
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02581
      Location:1 → 28
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

    18. NM_001370390.1 → NP_001357319.1  zinc finger protein 266 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AC011451
      Consensus CDS
      CCDS12213.1
      UniProtKB/Swiss-Prot
      A0AV90, A4FU85, Q14584, Q6IQ07, Q6U8A5, Q8IVG3, Q8WVX1, Q96SX9
      Conserved Domains (4) summary
      COG5048
      Location:210 → 549
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:382 → 402
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:132 → 150
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02581
      Location:1 → 28
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

    19. NM_001370391.1 → NP_001357320.1  zinc finger protein 266 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AC011451
      Consensus CDS
      CCDS12213.1
      UniProtKB/Swiss-Prot
      A0AV90, A4FU85, Q14584, Q6IQ07, Q6U8A5, Q8IVG3, Q8WVX1, Q96SX9
      Conserved Domains (4) summary
      COG5048
      Location:210 → 549
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:382 → 402
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:132 → 150
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02581
      Location:1 → 28
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

    20. NM_001370392.1 → NP_001357321.1  zinc finger protein 266 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AC011451
      Consensus CDS
      CCDS12213.1
      UniProtKB/Swiss-Prot
      A0AV90, A4FU85, Q14584, Q6IQ07, Q6U8A5, Q8IVG3, Q8WVX1, Q96SX9
      Conserved Domains (4) summary
      COG5048
      Location:210 → 549
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:382 → 402
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:132 → 150
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02581
      Location:1 → 28
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

    21. NM_001370393.1 → NP_001357322.1  zinc finger protein 266 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AC011451
      Consensus CDS
      CCDS12213.1
      UniProtKB/Swiss-Prot
      A0AV90, A4FU85, Q14584, Q6IQ07, Q6U8A5, Q8IVG3, Q8WVX1, Q96SX9
      Conserved Domains (4) summary
      COG5048
      Location:210 → 549
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:382 → 402
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:132 → 150
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02581
      Location:1 → 28
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

    22. NM_001370394.1 → NP_001357323.1  zinc finger protein 266 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AC011451
      Consensus CDS
      CCDS12213.1
      UniProtKB/Swiss-Prot
      A0AV90, A4FU85, Q14584, Q6IQ07, Q6U8A5, Q8IVG3, Q8WVX1, Q96SX9
      Conserved Domains (4) summary
      COG5048
      Location:210 → 549
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:382 → 402
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:132 → 150
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02581
      Location:1 → 28
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

    23. NM_001370395.1 → NP_001357324.1  zinc finger protein 266 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AC011451
      Consensus CDS
      CCDS12213.1
      UniProtKB/Swiss-Prot
      A0AV90, A4FU85, Q14584, Q6IQ07, Q6U8A5, Q8IVG3, Q8WVX1, Q96SX9
      Conserved Domains (4) summary
      COG5048
      Location:210 → 549
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:382 → 402
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:132 → 150
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02581
      Location:1 → 28
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

    24. NM_001370396.1 → NP_001357325.1  zinc finger protein 266 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AC011451
      Consensus CDS
      CCDS12213.1
      UniProtKB/Swiss-Prot
      A0AV90, A4FU85, Q14584, Q6IQ07, Q6U8A5, Q8IVG3, Q8WVX1, Q96SX9
      Conserved Domains (4) summary
      COG5048
      Location:210 → 549
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:382 → 402
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:132 → 150
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02581
      Location:1 → 28
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

    25. NM_001370397.1 → NP_001357326.1  zinc finger protein 266 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AC011451
      Consensus CDS
      CCDS12213.1
      UniProtKB/Swiss-Prot
      A0AV90, A4FU85, Q14584, Q6IQ07, Q6U8A5, Q8IVG3, Q8WVX1, Q96SX9
      Conserved Domains (4) summary
      COG5048
      Location:210 → 549
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:382 → 402
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:132 → 150
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02581
      Location:1 → 28
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

    26. NM_001370398.1 → NP_001357327.1  zinc finger protein 266 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AC011451
      Consensus CDS
      CCDS12213.1
      UniProtKB/Swiss-Prot
      A0AV90, A4FU85, Q14584, Q6IQ07, Q6U8A5, Q8IVG3, Q8WVX1, Q96SX9
      Conserved Domains (4) summary
      COG5048
      Location:210 → 549
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:382 → 402
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:132 → 150
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02581
      Location:1 → 28
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

    27. NM_001370399.1 → NP_001357328.1  zinc finger protein 266 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AC011451
      Consensus CDS
      CCDS12213.1
      UniProtKB/Swiss-Prot
      A0AV90, A4FU85, Q14584, Q6IQ07, Q6U8A5, Q8IVG3, Q8WVX1, Q96SX9
      Conserved Domains (4) summary
      COG5048
      Location:210 → 549
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:382 → 402
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:132 → 150
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02581
      Location:1 → 28
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

    28. NM_001370400.1 → NP_001357329.1  zinc finger protein 266 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AC011451
      Consensus CDS
      CCDS12213.1
      UniProtKB/Swiss-Prot
      A0AV90, A4FU85, Q14584, Q6IQ07, Q6U8A5, Q8IVG3, Q8WVX1, Q96SX9
      Conserved Domains (4) summary
      COG5048
      Location:210 → 549
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:382 → 402
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:132 → 150
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02581
      Location:1 → 28
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

    29. NM_006631.4 → NP_006622.2  zinc finger protein 266 isoform 1

      See identical proteins and their annotated locations for NP_006622.2

      Status: REVIEWED

      Source sequence(s)
      AC011451, AY376240, CN484252
      Consensus CDS
      CCDS12213.1
      UniProtKB/Swiss-Prot
      A0AV90, A4FU85, Q14584, Q6IQ07, Q6U8A5, Q8IVG3, Q8WVX1, Q96SX9
      Related
      ENSP00000467315.1, ENST00000590306.5
      Conserved Domains (4) summary
      COG5048
      Location:210 → 549
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:382 → 402
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:132 → 150
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02581
      Location:1 → 28
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

      Range
      9412429..9435573 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006722623.4 → XP_006722686.1  zinc finger protein 266 isoform X1

      See identical proteins and their annotated locations for XP_006722686.1

      UniProtKB/TrEMBL
      A0A3F2YPB8
      Conserved Domains (4) summary
      smart00349
      Location:39 → 95
      KRAB; krueppel associated box
      COG5048
      Location:277 → 616
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:449 → 469
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:199 → 217
      ZF_C2H2; C2H2 Zn finger [structural motif]

    2. XM_047438069.1 → XP_047294025.1  zinc finger protein 266 isoform X1

      UniProtKB/TrEMBL
      A0A3F2YPB8

    3. XM_047438068.1 → XP_047294024.1  zinc finger protein 266 isoform X1

      UniProtKB/TrEMBL
      A0A3F2YPB8

    4. XM_047438066.1 → XP_047294022.1  zinc finger protein 266 isoform X1

      UniProtKB/TrEMBL
      A0A3F2YPB8

    5. XM_047438074.1 → XP_047294030.1  zinc finger protein 266 isoform X2

      UniProtKB/Swiss-Prot
      A0AV90, A4FU85, Q14584, Q6IQ07, Q6U8A5, Q8IVG3, Q8WVX1, Q96SX9

    6. XM_011527650.1 → XP_011525952.1  zinc finger protein 266 isoform X2

      See identical proteins and their annotated locations for XP_011525952.1

      UniProtKB/Swiss-Prot
      A0AV90, A4FU85, Q14584, Q6IQ07, Q6U8A5, Q8IVG3, Q8WVX1, Q96SX9
      Conserved Domains (4) summary
      COG5048
      Location:210 → 549
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:382 → 402
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:132 → 150
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl02581
      Location:1 → 28
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

    7. XM_047438070.1 → XP_047294026.1  zinc finger protein 266 isoform X2

      UniProtKB/Swiss-Prot
      A0AV90, A4FU85, Q14584, Q6IQ07, Q6U8A5, Q8IVG3, Q8WVX1, Q96SX9

    8. XM_047438071.1 → XP_047294027.1  zinc finger protein 266 isoform X2

      UniProtKB/Swiss-Prot
      A0AV90, A4FU85, Q14584, Q6IQ07, Q6U8A5, Q8IVG3, Q8WVX1, Q96SX9

    9. XM_047438073.1 → XP_047294029.1  zinc finger protein 266 isoform X2

      UniProtKB/Swiss-Prot
      A0AV90, A4FU85, Q14584, Q6IQ07, Q6U8A5, Q8IVG3, Q8WVX1, Q96SX9

    10. XM_047438072.1 → XP_047294028.1  zinc finger protein 266 isoform X2

      UniProtKB/Swiss-Prot
      A0AV90, A4FU85, Q14584, Q6IQ07, Q6U8A5, Q8IVG3, Q8WVX1, Q96SX9

    11. XM_006722620.2 → XP_006722683.1  zinc finger protein 266 isoform X1

      See identical proteins and their annotated locations for XP_006722683.1

      UniProtKB/TrEMBL
      A0A3F2YPB8
      Conserved Domains (4) summary
      smart00349
      Location:39 → 95
      KRAB; krueppel associated box
      COG5048
      Location:277 → 616
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:449 → 469
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:199 → 217
      ZF_C2H2; C2H2 Zn finger [structural motif]

    12. XM_017026173.2 → XP_016881662.1  zinc finger protein 266 isoform X3

      Conserved Domains (1) summary
      smart00349
      Location:39 → 95
      KRAB; krueppel associated box

    13. XM_011527644.1 → XP_011525946.1  zinc finger protein 266 isoform X1

      See identical proteins and their annotated locations for XP_011525946.1

      UniProtKB/TrEMBL
      A0A3F2YPB8
      Conserved Domains (4) summary
      smart00349
      Location:39 → 95
      KRAB; krueppel associated box
      COG5048
      Location:277 → 616
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:449 → 469
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:199 → 217
      ZF_C2H2; C2H2 Zn finger [structural motif]

    14. XM_047438065.1 → XP_047294021.1  zinc finger protein 266 isoform X1

      UniProtKB/TrEMBL
      A0A3F2YPB8

    15. XM_047438067.1 → XP_047294023.1  zinc finger protein 266 isoform X1

      UniProtKB/TrEMBL
      A0A3F2YPB8

    16. XM_047438064.1 → XP_047294020.1  zinc finger protein 266 isoform X1

      UniProtKB/TrEMBL
      A0A3F2YPB8

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060943.1 Alternate T2T-CHM13v2.0

      Range
      9538632..9561760 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054319558.1 → XP_054175533.1  zinc finger protein 266 isoform X1

      UniProtKB/TrEMBL
      A0A3F2YPB8

    2. XM_054319559.1 → XP_054175534.1  zinc finger protein 266 isoform X1

      UniProtKB/TrEMBL
      A0A3F2YPB8

    3. XM_054319557.1 → XP_054175532.1  zinc finger protein 266 isoform X1

      UniProtKB/TrEMBL
      A0A3F2YPB8

    4. XM_054319555.1 → XP_054175530.1  zinc finger protein 266 isoform X1

      UniProtKB/TrEMBL
      A0A3F2YPB8

    5. XM_054319565.1 → XP_054175540.1  zinc finger protein 266 isoform X2

      UniProtKB/Swiss-Prot
      A0AV90, A4FU85, Q14584, Q6IQ07, Q6U8A5, Q8IVG3, Q8WVX1, Q96SX9

    6. XM_054319564.1 → XP_054175539.1  zinc finger protein 266 isoform X2

      UniProtKB/Swiss-Prot
      A0AV90, A4FU85, Q14584, Q6IQ07, Q6U8A5, Q8IVG3, Q8WVX1, Q96SX9

    7. XM_054319560.1 → XP_054175535.1  zinc finger protein 266 isoform X2

      UniProtKB/Swiss-Prot
      A0AV90, A4FU85, Q14584, Q6IQ07, Q6U8A5, Q8IVG3, Q8WVX1, Q96SX9

    8. XM_054319561.1 → XP_054175536.1  zinc finger protein 266 isoform X2

      UniProtKB/Swiss-Prot
      A0AV90, A4FU85, Q14584, Q6IQ07, Q6U8A5, Q8IVG3, Q8WVX1, Q96SX9

    9. XM_054319563.1 → XP_054175538.1  zinc finger protein 266 isoform X2

      UniProtKB/Swiss-Prot
      A0AV90, A4FU85, Q14584, Q6IQ07, Q6U8A5, Q8IVG3, Q8WVX1, Q96SX9

    10. XM_054319562.1 → XP_054175537.1  zinc finger protein 266 isoform X2

      UniProtKB/Swiss-Prot
      A0AV90, A4FU85, Q14584, Q6IQ07, Q6U8A5, Q8IVG3, Q8WVX1, Q96SX9

    11. XM_054319551.1 → XP_054175526.1  zinc finger protein 266 isoform X1

      UniProtKB/TrEMBL
      A0A3F2YPB8

    12. XM_054319566.1 → XP_054175541.1  zinc finger protein 266 isoform X3

    13. XM_054319554.1 → XP_054175529.1  zinc finger protein 266 isoform X1

      UniProtKB/TrEMBL
      A0A3F2YPB8

    14. XM_054319553.1 → XP_054175528.1  zinc finger protein 266 isoform X1

      UniProtKB/TrEMBL
      A0A3F2YPB8

    15. XM_054319556.1 → XP_054175531.1  zinc finger protein 266 isoform X1

      UniProtKB/TrEMBL
      A0A3F2YPB8

    16. XM_054319552.1 → XP_054175527.1  zinc finger protein 266 isoform X1

      UniProtKB/TrEMBL
      A0A3F2YPB8

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_198058.1: Suppressed sequence

      Description
      NM_198058.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q14584.2 GenPept UniProtKB/Swiss-Prot:Q14584

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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