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    MIR6747 microRNA 6747 [ Homo sapiens (human) ]

    Gene ID: 102465447, updated on 17-Sep-2024

    Summary

    Official Symbol
    MIR6747provided by HGNC
    Official Full Name
    microRNA 6747provided by HGNC
    Primary source
    HGNC:HGNC:50027
    See related
    Ensembl:ENSG00000276102 miRBase:MI0022592; AllianceGenome:HGNC:50027
    Gene type
    ncRNA
    RefSeq status
    PROVISIONAL
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    hsa-mir-6747
    Summary
    microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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    Genomic context

    See MIR6747 in Genome Data Viewer
    Location:
    11q12.3
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (62567011..62567071, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (62556463..62556523, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (62334483..62334543, complement)

    Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102723765 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4815 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4816 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:62193633-62194180 Neighboring gene secretoglobin family 1A member 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:62201545-62202046 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:62202047-62202546 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4817 Neighboring gene Sharpr-MPRA regulatory region 7741 Neighboring gene AHNAK nucleoprotein Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:62273135-62273882 Neighboring gene Sharpr-MPRA regulatory region 266 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr11:62302796-62303995 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:62306574-62307176 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:62307177-62307777 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4818 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4819 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:62312785-62313295 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:62313296-62313806 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:62314385-62314915 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3414 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3415 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:62318643-62319448 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:62319449-62320254 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3416 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:62323477-62324282 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:62324283-62325086 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:62325319-62325834 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:62326954-62327496 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4824 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:62329123-62329665 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4825 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:62341487-62342448 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:62342449-62343410 Neighboring gene eukaryotic translation elongation factor 1 gamma Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:62358805-62359500 Neighboring gene terminal uridylyl transferase 1, U6 snRNA-specific Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4828 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:62368208-62368918 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3419 Neighboring gene metastasis associated 1 family member 2

    Genomic regions, transcripts, and products

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_106805.1 RNA Sequence

      Status: PROVISIONAL

      Source sequence(s)
      AP002990
      Related
      ENST00000617193.1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

      Range
      62567011..62567071 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060935.1 Alternate T2T-CHM13v2.0

      Range
      62556463..62556523 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)