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    ARPC3 actin related protein 2/3 complex subunit 3 [ Canis lupus familiaris (dog) ]

    Gene ID: 100856747, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ARPC3provided by VGNC
    Official Full Name
    actin related protein 2/3 complex subunit 3provided by VGNC
    Primary source
    VGNC:VGNC:111347
    See related
    Ensembl:ENSCAFG00845027962
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See ARPC3 in Genome Data Viewer
    Location:
    chromosome: 26
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 26 NC_051830.1 (8524788..8535469, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 26 NC_006608.4 (8430745..8441421, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 26 NC_049247.1 (8497864..8508751, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 26 NC_049286.1 (8484142..8494810, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 26 NC_049767.1 (8542697..8553529, complement)

    Chromosome 26 - NC_051830.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102153400 Neighboring gene anaphase promoting complex subunit 7 Neighboring gene GPN-loop GTPase 3 Neighboring gene family with sequence similarity 216 member A Neighboring gene VPS29 retromer complex component

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables actin filament binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Arp2/3 complex-mediated actin nucleation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of actin filament polymerization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Arp2/3 protein complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    actin-related protein 2/3 complex subunit 3
    Names
    actin related protein 2/3 complex, subunit 3, 21kDa

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051830.1 Reference ROS_Cfam_1.0

      Range
      8524788..8535469 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038436625.1 → XP_038292553.1  actin-related protein 2/3 complex subunit 3 isoform X1

      UniProtKB/TrEMBL
      A0A8C0Z2Q6, A0A8I3PVA8, A0A8I3Q467
      Related
      ENSCAFP00845038723.1, ENSCAFT00845049350.1
      Conserved Domains (1) summary
      pfam04062
      Location:2 → 186
      P21-Arc; ARP2/3 complex ARPC3 (21 kDa) subunit

    2. XM_038436626.1 → XP_038292554.1  actin-related protein 2/3 complex subunit 3 isoform X2

      UniProtKB/TrEMBL
      A0A8C0RRY4, A0A8C0Z2Q6, A0A8I3Q467
      Related
      ENSCAFP00845038807.1, ENSCAFT00845049459.1
      Conserved Domains (1) summary
      pfam04062
      Location:1 → 173
      P21-Arc; ARP2/3 complex ARPC3 (21 kDa) subunit

    3. XM_038436627.1 → XP_038292555.1  actin-related protein 2/3 complex subunit 3 isoform X3

      UniProtKB/TrEMBL
      A0A8C0Z2Q6, A0A8I3Q467
      Conserved Domains (1) summary
      pfam04062
      Location:2 → 172
      P21-Arc; ARP2/3 complex ARPC3 (21 kDa) subunit

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049286.1 Alternate UMICH_Zoey_3.1

      Range
      8484142..8494810 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038511541.1 → XP_038367469.1  actin-related protein 2/3 complex subunit 3 isoform X1

      Conserved Domains (1) summary
      pfam04062
      Location:2 → 186
      P21-Arc; ARP2/3 complex ARPC3 (21 kDa) subunit

    2. XM_038511542.1 → XP_038367470.1  actin-related protein 2/3 complex subunit 3 isoform X2

      Conserved Domains (1) summary
      pfam04062
      Location:1 → 173
      P21-Arc; ARP2/3 complex ARPC3 (21 kDa) subunit

    3. XM_038511543.1 → XP_038367471.1  actin-related protein 2/3 complex subunit 3 isoform X3

      Conserved Domains (1) summary
      pfam04062
      Location:2 → 172
      P21-Arc; ARP2/3 complex ARPC3 (21 kDa) subunit

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049767.1 Alternate UNSW_CanFamBas_1.0

      Range
      8542697..8553529 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038639219.1 → XP_038495147.1  actin-related protein 2/3 complex subunit 3 isoform X1

      Conserved Domains (1) summary
      pfam04062
      Location:2 → 186
      P21-Arc; ARP2/3 complex ARPC3 (21 kDa) subunit

    2. XM_038639220.1 → XP_038495148.1  actin-related protein 2/3 complex subunit 3 isoform X2

      Conserved Domains (1) summary
      pfam04062
      Location:1 → 173
      P21-Arc; ARP2/3 complex ARPC3 (21 kDa) subunit

    3. XM_038639221.1 → XP_038495149.1  actin-related protein 2/3 complex subunit 3 isoform X3

      Conserved Domains (1) summary
      pfam04062
      Location:2 → 172
      P21-Arc; ARP2/3 complex ARPC3 (21 kDa) subunit

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049247.1 Alternate UU_Cfam_GSD_1.0

      Range
      8497864..8508751 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038575040.1 → XP_038430968.1  actin-related protein 2/3 complex subunit 3 isoform X1

      UniProtKB/TrEMBL
      A0A8C0Z2Q6, A0A8I3PVA8, A0A8I3Q467
      Conserved Domains (1) summary
      pfam04062
      Location:2 → 186
      P21-Arc; ARP2/3 complex ARPC3 (21 kDa) subunit

    2. XM_038575041.1 → XP_038430969.1  actin-related protein 2/3 complex subunit 3 isoform X2

      UniProtKB/TrEMBL
      A0A8C0RRY4, A0A8C0Z2Q6, A0A8I3Q467
      Conserved Domains (1) summary
      pfam04062
      Location:1 → 173
      P21-Arc; ARP2/3 complex ARPC3 (21 kDa) subunit

    3. XM_038575042.1 → XP_038430970.1  actin-related protein 2/3 complex subunit 3 isoform X3

      UniProtKB/TrEMBL
      A0A8C0Z2Q6, A0A8I3Q467
      Conserved Domains (1) summary
      pfam04062
      Location:2 → 172
      P21-Arc; ARP2/3 complex ARPC3 (21 kDa) subunit

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006608.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      8430745..8441421 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_022410435.2 → XP_022266143.1  actin-related protein 2/3 complex subunit 3 isoform X1

      UniProtKB/TrEMBL
      A0A8C0Z2Q6, A0A8I3PVA8, A0A8I3Q467
      Conserved Domains (1) summary
      pfam04062
      Location:2 → 186
      P21-Arc; ARP2/3 complex ARPC3 (21 kDa) subunit

    2. XM_003639909.5 → XP_003639957.1  actin-related protein 2/3 complex subunit 3 isoform X2

      See identical proteins and their annotated locations for XP_003639957.1

      UniProtKB/TrEMBL
      A0A8C0RRY4, A0A8C0Z2Q6, A0A8I3Q467
      Conserved Domains (1) summary
      pfam04062
      Location:1 → 173
      P21-Arc; ARP2/3 complex ARPC3 (21 kDa) subunit

    3. XM_014108091.3 → XP_013963566.1  actin-related protein 2/3 complex subunit 3 isoform X3

      UniProtKB/TrEMBL
      A0A8C0Z2Q6, A0A8I3Q467
      Conserved Domains (1) summary
      pfam04062
      Location:2 → 172
      P21-Arc; ARP2/3 complex ARPC3 (21 kDa) subunit
    Nucleotide Protein
    Heading Accession and Version

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