RPA2 replication protein A2 [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: RPA2provided by VGNC
Official Full Name: replication protein A2provided by VGNC
Primary source: VGNC:VGNC:45703
See related: Ensembl:ENSCAFG00845011391
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	2	NC_051806.1 (73023824..73039936)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	2	NC_006584.4 (69041511..69057436)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	2	NC_049223.1 (71857687..71874007)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	2	NC_049262.1 (69851237..69867152)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	2	NC_049743.1 (70861509..70877423)

Chromosome 2 - NC_051806.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in DNA replication	IEA Inferred from Electronic Annotation more info	PubMed
involved_in double-strand break repair via homologous recombination	IEA Inferred from Electronic Annotation more info	PubMed
involved_in nucleotide-excision repair	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of DNA replication factor A complex	IEA Inferred from Electronic Annotation more info	PubMed
located_in chromosome, telomeric region	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed
located_in site of double-strand break	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: replication protein A 32 kDa subunit

Names: replication protein A2, 32kDa

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051806.1 Reference ROS_Cfam_1.0

Range

73023824..73039936

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038659690.1 → XP_038515618.1 replication protein A 32 kDa subunit

UniProtKB/TrEMBL

A0A8C0LGC0, A0A8C0MXK7, A0A8I3N802

Related

ENSCAFP00845015880.1, ENSCAFT00845020258.1

Conserved Domains (2) summary

COG5235
Location:11 → 267

RFA2; Single-stranded DNA-binding replication protein A (RPA), medium (30 kD) subunit [DNA replication, recombination, and repair]

cd04478
Location:73 → 167

RPA2_DBD_D; A subfamily of OB folds corresponding to the OB fold of the central ssDNA-binding domain (DBD)-D of human RPA2 (also called RPA32). RPA2 is a subunit of Replication protein A (RPA). RPA is a nuclear ssDNA-binding protein (SSB) which appears to be ...

Alternate UMICH_Zoey_3.1

Genomic

NC_049262.1 Alternate UMICH_Zoey_3.1

Range

69851237..69867152

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038470544.1 → XP_038326472.1 replication protein A 32 kDa subunit

Conserved Domains (2) summary

COG5235
Location:11 → 267

RFA2; Single-stranded DNA-binding replication protein A (RPA), medium (30 kD) subunit [DNA replication, recombination, and repair]

cd04478
Location:73 → 167

RPA2_DBD_D; A subfamily of OB folds corresponding to the OB fold of the central ssDNA-binding domain (DBD)-D of human RPA2 (also called RPA32). RPA2 is a subunit of Replication protein A (RPA). RPA is a nuclear ssDNA-binding protein (SSB) which appears to be ...

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049743.1 Alternate UNSW_CanFamBas_1.0

Range

70861509..70877423

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038595609.1 → XP_038451537.1 replication protein A 32 kDa subunit

Conserved Domains (2) summary

COG5235
Location:11 → 267

RFA2; Single-stranded DNA-binding replication protein A (RPA), medium (30 kD) subunit [DNA replication, recombination, and repair]

cd04478
Location:73 → 167

RPA2_DBD_D; A subfamily of OB folds corresponding to the OB fold of the central ssDNA-binding domain (DBD)-D of human RPA2 (also called RPA32). RPA2 is a subunit of Replication protein A (RPA). RPA is a nuclear ssDNA-binding protein (SSB) which appears to be ...

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049223.1 Alternate UU_Cfam_GSD_1.0

Range

71857687..71874007

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038531388.1 → XP_038387316.1 replication protein A 32 kDa subunit

UniProtKB/TrEMBL

A0A8C0LGC0, A0A8C0MXK7, A0A8I3N802

Conserved Domains (2) summary

COG5235
Location:11 → 267

RFA2; Single-stranded DNA-binding replication protein A (RPA), medium (30 kD) subunit [DNA replication, recombination, and repair]

cd04478
Location:73 → 167

RPA2_DBD_D; A subfamily of OB folds corresponding to the OB fold of the central ssDNA-binding domain (DBD)-D of human RPA2 (also called RPA32). RPA2 is a subunit of Replication protein A (RPA). RPA is a nuclear ssDNA-binding protein (SSB) which appears to be ...

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006584.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

69041511..69057436

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_003638940.5 → XP_003638988.1 replication protein A 32 kDa subunit

UniProtKB/TrEMBL

A0A8C0LGC0, A0A8P0TDG2

Conserved Domains (3) summary

COG5235
Location:25 → 267

RFA2; Single-stranded DNA-binding replication protein A (RPA), medium (30 kD) subunit [DNA replication, recombination, and repair]

cd04478
Location:73 → 167

RPA2_DBD_D; RPA2_DBD_D: A subfamily of OB folds corresponding to the OB fold of the central ssDNA-binding domain (DBD)-D of human RPA2 (also called RPA32). RPA2 is a subunit of Replication protein A (RPA). RPA is a nuclear ssDNA-binding protein (SSB) which appears ...

pfam08784
Location:166 → 262

RPA_C; Replication protein A C terminal