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    BMP3 bone morphogenetic protein 3 [ Canis lupus familiaris (dog) ]

    Gene ID: 100855862, updated on 17-Aug-2024

    Summary

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    Official Symbol
    BMP3provided by VGNC
    Official Full Name
    bone morphogenetic protein 3provided by VGNC
    Primary source
    VGNC:VGNC:57398
    See related
    Ensembl:ENSCAFG00845017996
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See BMP3 in Genome Data Viewer
    Location:
    chromosome: 32
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 32 NC_051836.1 (5238247..5266418)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 32 NC_006614.4 (36645845..36674004, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 32 NC_049253.1 (34764153..34792337, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 32 NC_049292.1 (5267894..5294547)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 32 NC_049773.1 (5175043..5202995)

    Chromosome 32 - NC_051836.1Genomic Context describing neighboring genes Neighboring gene cilia and flagella associated protein 299 Neighboring gene uncharacterized LOC119867173 Neighboring gene MICOS complex subunit MIC27-like Neighboring gene protein kinase cGMP-dependent 2 Neighboring gene RasGEF domain family member 1B Neighboring gene 60S ribosomal protein L37a-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Variation of BMP3 contributes to dog breed skull diversity. Schoenebeck JJ, et al. PLoS Genet, 2012. PMID 22876193, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Canine brachycephaly is caused by a missense mutation in the gene BMP3.
      Title: Variation of BMP3 contributes to dog breed skull diversity.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cytokine activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables growth factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in BMP signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in SMAD protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in osteoblast differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    bone morphogenetic protein 3
    Names
    bone morphogenetic protein 3 (osteogenic)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051836.1 Reference ROS_Cfam_1.0

      Range
      5238247..5266418
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038443947.1 → XP_038299875.1  bone morphogenetic protein 3

      UniProtKB/TrEMBL
      A0A8C0KCR6, A0A8C0NIS2, A0A8I3PA06
      Related
      ENSCAFP00845024925.1, ENSCAFT00845031860.1
      Conserved Domains (1) summary
      cd19393
      Location:366 → 475
      TGF_beta_BMP3; transforming growth factor beta (TGF-beta) like domain found in bone morphogenetic protein 3 (BMP-3) and similar proteins

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049292.1 Alternate UMICH_Zoey_3.1

      Range
      5267894..5294547
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038518348.1 → XP_038374276.1  bone morphogenetic protein 3

      Conserved Domains (1) summary
      cd19393
      Location:366 → 475
      TGF_beta_BMP3; transforming growth factor beta (TGF-beta) like domain found in bone morphogenetic protein 3 (BMP-3) and similar proteins

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049773.1 Alternate UNSW_CanFamBas_1.0

      Range
      5175043..5202995
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038646277.1 → XP_038502205.1  bone morphogenetic protein 3

      Conserved Domains (1) summary
      cd19393
      Location:366 → 475
      TGF_beta_BMP3; transforming growth factor beta (TGF-beta) like domain found in bone morphogenetic protein 3 (BMP-3) and similar proteins

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049253.1 Alternate UU_Cfam_GSD_1.0

      Range
      34764153..34792337 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038582313.1 → XP_038438241.1  bone morphogenetic protein 3

      UniProtKB/TrEMBL
      A0A8C0KCR6, A0A8C0NIS2, A0A8I3PA06
      Conserved Domains (1) summary
      cd19393
      Location:366 → 475
      TGF_beta_BMP3; transforming growth factor beta (TGF-beta) like domain found in bone morphogenetic protein 3 (BMP-3) and similar proteins

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006614.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      36645845..36674004 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038462141.1 → XP_038318069.1  bone morphogenetic protein 3

      UniProtKB/TrEMBL
      A0A8C0KCR6, A0A8C0NIS2, A0A8I3PA06
      Conserved Domains (1) summary
      cd19393
      Location:366 → 475
      TGF_beta_BMP3; transforming growth factor beta (TGF-beta) like domain found in bone morphogenetic protein 3 (BMP-3) and similar proteins
    Nucleotide Protein
    Heading Accession and Version

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