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    LZIC leucine zipper and CTNNBIP1 domain containing [ Canis lupus familiaris (dog) ]

    Gene ID: 100855658, updated on 8-Mar-2024

    Summary

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    Official Symbol
    LZICprovided by VGNC
    Official Full Name
    leucine zipper and CTNNBIP1 domain containingprovided by VGNC
    Primary source
    VGNC:VGNC:42903
    See related
    Ensembl:ENSCAFG00845000392
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See LZIC in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 5 NC_051809.1 (63337691..63349210, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 5 NC_006587.4 (63126153..63137847, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 5 NC_049226.1 (63601922..63613447, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 5 NC_049265.1 (63358603..63370114, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 5 NC_049746.1 (63198129..63209799, complement)

    Chromosome 5 - NC_051809.1Genomic Context describing neighboring genes Neighboring gene beta-catenin-interacting protein 1 Neighboring gene uncharacterized LOC111095992 Neighboring gene uncharacterized LOC119871913 Neighboring gene nicotinamide nucleotide adenylyltransferase 1 Neighboring gene uncharacterized LOC119871914 Neighboring gene retinol binding protein 7

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables beta-catenin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of beta-catenin destruction complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein LZIC

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051809.1 Reference ROS_Cfam_1.0

      Range
      63337691..63349210 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038666681.1 → XP_038522609.1  protein LZIC isoform X4

      UniProtKB/TrEMBL
      A0A8I3MKE3, A0A8P0PKD3
      Related
      ENSCAFP00845000441.1, ENSCAFT00845000629.1
      Conserved Domains (1) summary
      pfam06384
      Location:134 → 209
      ICAT; Beta-catenin-interacting protein ICAT

    2. XM_038666675.1 → XP_038522603.1  protein LZIC isoform X1

      UniProtKB/TrEMBL
      A0A8C0SSA3
      Conserved Domains (1) summary
      pfam06384
      Location:147 → 222
      ICAT; Beta-catenin-interacting protein ICAT

    3. XM_038666677.1 → XP_038522605.1  protein LZIC isoform X2

      UniProtKB/TrEMBL
      A0A8C0MM96, A0A8C0SPJ5, A0A8P0PRR2
      Conserved Domains (1) summary
      pfam06384
      Location:134 → 209
      ICAT; Beta-catenin-interacting protein ICAT

    4. XM_038666676.1 → XP_038522604.1  protein LZIC isoform X1

      UniProtKB/TrEMBL
      A0A8C0SSA3
      Conserved Domains (1) summary
      pfam06384
      Location:147 → 222
      ICAT; Beta-catenin-interacting protein ICAT

    5. XM_038666680.1 → XP_038522608.1  protein LZIC isoform X3

      UniProtKB/TrEMBL
      A0A8C0K0M9, A0A8I3MAN6, A0A8I3MKE3, A0A8P0PI55, A0A8P0PKD3
      Conserved Domains (1) summary
      pfam06384
      Location:113 → 188
      ICAT; Beta-catenin-interacting protein ICAT

    6. XM_038666679.1 → XP_038522607.1  protein LZIC isoform X3

      UniProtKB/TrEMBL
      A0A8C0K0M9, A0A8I3MAN6, A0A8I3MKE3, A0A8P0PI55, A0A8P0PKD3
      Related
      ENSCAFP00845000420.1, ENSCAFT00845000605.1
      Conserved Domains (1) summary
      pfam06384
      Location:113 → 188
      ICAT; Beta-catenin-interacting protein ICAT

    7. XM_038666678.1 → XP_038522606.1  protein LZIC isoform X3

      UniProtKB/TrEMBL
      A0A8C0K0M9, A0A8I3MAN6, A0A8I3MKE3, A0A8P0PI55, A0A8P0PKD3
      Conserved Domains (1) summary
      pfam06384
      Location:113 → 188
      ICAT; Beta-catenin-interacting protein ICAT

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049265.1 Alternate UMICH_Zoey_3.1

      Range
      63358603..63370114 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038476782.1 → XP_038332710.1  protein LZIC isoform X4

    2. XM_038476777.1 → XP_038332705.1  protein LZIC isoform X2

    3. XM_038476775.1 → XP_038332703.1  protein LZIC isoform X5

    4. XM_038476776.1 → XP_038332704.1  protein LZIC isoform X1

    5. XM_038476781.1 → XP_038332709.1  protein LZIC isoform X3

      Conserved Domains (1) summary
      pfam06384
      Location:113 → 188
      ICAT; Beta-catenin-interacting protein ICAT

    6. XM_038476779.1 → XP_038332707.1  protein LZIC isoform X3

      Conserved Domains (1) summary
      pfam06384
      Location:113 → 188
      ICAT; Beta-catenin-interacting protein ICAT

    7. XM_038476778.1 → XP_038332706.1  protein LZIC isoform X3

      Conserved Domains (1) summary
      pfam06384
      Location:113 → 188
      ICAT; Beta-catenin-interacting protein ICAT

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049746.1 Alternate UNSW_CanFamBas_1.0

      Range
      63198129..63209799 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038602075.1 → XP_038458003.1  protein LZIC isoform X4

      Conserved Domains (1) summary
      pfam06384
      Location:134 → 209
      ICAT; Beta-catenin-interacting protein ICAT

    2. XM_038602071.1 → XP_038457999.1  protein LZIC isoform X2

      Conserved Domains (1) summary
      pfam06384
      Location:134 → 209
      ICAT; Beta-catenin-interacting protein ICAT

    3. XM_038602069.1 → XP_038457997.1  protein LZIC isoform X6

    4. XM_038602070.1 → XP_038457998.1  protein LZIC isoform X1

    5. XM_038602074.1 → XP_038458002.1  protein LZIC isoform X3

      Conserved Domains (1) summary
      pfam06384
      Location:113 → 188
      ICAT; Beta-catenin-interacting protein ICAT

    6. XM_038602073.1 → XP_038458001.1  protein LZIC isoform X3

      Conserved Domains (1) summary
      pfam06384
      Location:113 → 188
      ICAT; Beta-catenin-interacting protein ICAT

    7. XM_038602072.1 → XP_038458000.1  protein LZIC isoform X3

      Conserved Domains (1) summary
      pfam06384
      Location:113 → 188
      ICAT; Beta-catenin-interacting protein ICAT

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049226.1 Alternate UU_Cfam_GSD_1.0

      Range
      63601922..63613447 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038537939.1 → XP_038393867.1  protein LZIC isoform X4

      UniProtKB/TrEMBL
      A0A8I3MKE3, A0A8P0PKD3
      Conserved Domains (1) summary
      pfam06384
      Location:134 → 209
      ICAT; Beta-catenin-interacting protein ICAT

    2. XM_038537934.1 → XP_038393862.1  protein LZIC isoform X2

      UniProtKB/TrEMBL
      A0A8C0MM96, A0A8C0SPJ5, A0A8P0PRR2
      Conserved Domains (1) summary
      pfam06384
      Location:134 → 209
      ICAT; Beta-catenin-interacting protein ICAT

    3. XM_038537932.1 → XP_038393860.1  protein LZIC isoform X7

      UniProtKB/TrEMBL
      A0A8C0SSA3

    4. XM_038537933.1 → XP_038393861.1  protein LZIC isoform X1

      UniProtKB/TrEMBL
      A0A8C0MI25, A0A8C0SSA3

    5. XM_038537938.1 → XP_038393866.1  protein LZIC isoform X3

      UniProtKB/TrEMBL
      A0A8C0K0M9, A0A8I3MAN6, A0A8I3MKE3, A0A8P0PI55, A0A8P0PKD3
      Conserved Domains (1) summary
      pfam06384
      Location:113 → 188
      ICAT; Beta-catenin-interacting protein ICAT

    6. XM_038537937.1 → XP_038393865.1  protein LZIC isoform X3

      UniProtKB/TrEMBL
      A0A8C0K0M9, A0A8I3MAN6, A0A8I3MKE3, A0A8P0PI55, A0A8P0PKD3
      Conserved Domains (1) summary
      pfam06384
      Location:113 → 188
      ICAT; Beta-catenin-interacting protein ICAT

    7. XM_038537936.1 → XP_038393864.1  protein LZIC isoform X3

      UniProtKB/TrEMBL
      A0A8C0K0M9, A0A8I3MAN6, A0A8I3MKE3, A0A8P0PI55, A0A8P0PKD3
      Conserved Domains (1) summary
      pfam06384
      Location:113 → 188
      ICAT; Beta-catenin-interacting protein ICAT

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006587.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      63126153..63137847 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_022419038.2 → XP_022274746.1  protein LZIC isoform X4

      UniProtKB/TrEMBL
      A0A8I3MKE3, A0A8P0PKD3
      Conserved Domains (1) summary
      pfam06384
      Location:134 → 209
      ICAT; Beta-catenin-interacting protein ICAT

    2. XM_003639059.5 → XP_003639107.2  protein LZIC isoform X2

      UniProtKB/TrEMBL
      A0A8C0MM96, A0A8C0SPJ5, A0A8P0PRR2
      Conserved Domains (1) summary
      pfam06384
      Location:134 → 209
      ICAT; Beta-catenin-interacting protein ICAT

    3. XM_014113920.3 → XP_013969395.1  protein LZIC isoform X8

      UniProtKB/TrEMBL
      A0A8C0SSA3
      Conserved Domains (1) summary
      pfam06384
      Location:178 → 253
      ICAT; Beta-catenin-interacting protein ICAT

    4. XM_014113921.3 → XP_013969396.1  protein LZIC isoform X1

      UniProtKB/TrEMBL
      A0A8C0MI25, A0A8C0SSA3
      Conserved Domains (1) summary
      pfam06384
      Location:148 → 223
      ICAT; Beta-catenin-interacting protein ICAT

    5. XM_014113923.3 → XP_013969398.1  protein LZIC isoform X3

      UniProtKB/TrEMBL
      A0A8C0K0M9, A0A8I3MAN6, A0A8I3MKE3, A0A8P0PI55, A0A8P0PKD3
      Conserved Domains (1) summary
      pfam06384
      Location:113 → 188
      ICAT; Beta-catenin-interacting protein ICAT

    6. XM_022419037.2 → XP_022274745.1  protein LZIC isoform X3

      UniProtKB/TrEMBL
      A0A8C0K0M9, A0A8I3MAN6, A0A8I3MKE3, A0A8P0PI55, A0A8P0PKD3
      Conserved Domains (1) summary
      pfam06384
      Location:113 → 188
      ICAT; Beta-catenin-interacting protein ICAT

    7. XM_022419036.2 → XP_022274744.1  protein LZIC isoform X3

      UniProtKB/TrEMBL
      A0A8C0K0M9, A0A8I3MAN6, A0A8I3MKE3, A0A8P0PI55, A0A8P0PKD3
      Conserved Domains (1) summary
      pfam06384
      Location:113 → 188
      ICAT; Beta-catenin-interacting protein ICAT
    Nucleotide Protein
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