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    capn12 calpain 12 [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 100486294, updated on 4-Nov-2024

    Summary

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    Official Symbol
    capn12provided by Xenbase
    Official Full Name
    calpain 12provided by Xenbase
    Primary source
    Xenbase:XB-GENE-1008507
    See related
    Ensembl:ENSXETG00000034127 AllianceGenome:Xenbase:XB-GENE-1008507
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Summary
    Predicted to enable calcium-dependent cysteine-type endopeptidase activity. Predicted to act upstream of or within proteolysis. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See capn12 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 8 NC_030684.2 (80748341..80770244, complement)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 8 NC_030684.1 (59560460..59589350, complement)

    Chromosome 8 - NC_030684.2Genomic Context describing neighboring genes Neighboring gene lectin, galactoside-binding, soluble, 4, gene 2 Neighboring gene actinin alpha 4 Neighboring gene provisional ortholog of inositol-tetrakisphosphate 1-kinase Neighboring gene coiled-coil glutamate rich protein 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables calcium-dependent cysteine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables cysteine-type peptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    calpain-9

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030684.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      80748341..80770244 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_031890691.1 → XP_031746551.1  calpain-9 isoform X3

      UniProtKB/TrEMBL
      A0A803J6T4, A0A8J1IPX5
      Conserved Domains (3) summary
      cl25352
      Location:507 → 559
      EFh_PEF; The penta-EF hand (PEF) family
      pfam00648
      Location:33 → 327
      Peptidase_C2; Calpain family cysteine protease
      pfam01067
      Location:350 → 476
      Calpain_III; Calpain large subunit, domain III

    2. XM_031890690.1 → XP_031746550.1  calpain-9 isoform X2

      UniProtKB/TrEMBL
      A0A803J6T4, A0A8J1IP81
      Conserved Domains (3) summary
      cl25352
      Location:507 → 635
      EFh_PEF; The penta-EF hand (PEF) family
      pfam00648
      Location:33 → 327
      Peptidase_C2; Calpain family cysteine protease
      pfam01067
      Location:350 → 476
      Calpain_III; Calpain large subunit, domain III

    3. XM_031890688.1 → XP_031746548.1  calpain-9 isoform X1

      UniProtKB/TrEMBL
      A0A6I8PTX7, A0A803JBX4
      Related
      ENSXETP00000058420.3, ENSXETT00000065487.3
      Conserved Domains (3) summary
      cl25352
      Location:507 → 674
      EFh_PEF; The penta-EF hand (PEF) family
      pfam00648
      Location:33 → 327
      Peptidase_C2; Calpain family cysteine protease
      pfam01067
      Location:350 → 476
      Calpain_III; Calpain large subunit, domain III

    4. XM_031890687.1 → XP_031746547.1  calpain-9 isoform X1

      UniProtKB/TrEMBL
      A0A6I8PTX7, A0A803JBX4
      Conserved Domains (3) summary
      cl25352
      Location:507 → 674
      EFh_PEF; The penta-EF hand (PEF) family
      pfam00648
      Location:33 → 327
      Peptidase_C2; Calpain family cysteine protease
      pfam01067
      Location:350 → 476
      Calpain_III; Calpain large subunit, domain III

    5. XM_031890692.1 → XP_031746552.1  calpain-9 isoform X4

      UniProtKB/TrEMBL
      A0A8J1IM19
      Conserved Domains (3) summary
      cl25352
      Location:339 → 506
      EFh_PEF; The penta-EF hand (PEF) family
      pfam01067
      Location:182 → 308
      Calpain_III; Calpain large subunit, domain III
      cl00051
      Location:8 → 159
      CysPc; Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction.

    RNA

    1. XR_004219568.1 RNA Sequence

    2. XR_004219567.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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