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    Spink10 serine peptidase inhibitor, Kazal type 10 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 100361300, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Spink10provided by RGD
    Official Full Name
    serine peptidase inhibitor, Kazal type 10provided by RGD
    Primary source
    RGD:2320365
    See related
    EnsemblRapid:ENSRNOG00000043250 AllianceGenome:RGD:2320365
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be located in membrane. [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward (RPKM 7.4) See more
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    Genomic context

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    See Spink10 in Genome Data Viewer
    Location:
    18q12.1
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 18 NC_086036.1 (58370842..58381851)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 18 NC_051353.1 (56100535..56111771)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (57968119..57981976)

    Chromosome 18 - NC_086036.1Genomic Context describing neighboring genes Neighboring gene serine peptidase inhibitor, Kazal type 7 Neighboring gene serine peptidase inhibitor Kazal type 13 Neighboring gene proteasome 26S subunit, non-ATPase 14, pseudogene 1 Neighboring gene uncharacterized LOC108348798 Neighboring gene U6 spliceosomal RNA

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    serine protease inhibitor Kazal-type 10
    Names
    rCG46688-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086036.1 Reference GRCr8

      Range
      58370842..58381851
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002728560.5 → XP_002728606.3  serine protease inhibitor Kazal-type 10

      See identical proteins and their annotated locations for XP_002728606.3

      UniProtKB/TrEMBL
      A6IXK8, D3ZRP0
      Related
      ENSRNOP00000035896.5, ENSRNOT00000039466.7
      Conserved Domains (2) summary
      pfam00050
      Location:114 → 157
      Kazal_1; Kazal-type serine protease inhibitor domain
      cl00097
      Location:37 → 71
      KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...
    Nucleotide Protein Strain
    Heading Accession and Version

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