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    e2f8 E2F transcription factor 8 [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 100142691, updated on 4-Nov-2024

    Summary

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    Official Symbol
    e2f8provided by Xenbase
    Official Full Name
    E2F transcription factor 8provided by Xenbase
    Primary source
    Xenbase:XB-GENE-1219148
    See related
    Ensembl:ENSXETG00000004436 AllianceGenome:Xenbase:XB-GENE-1219148
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Summary
    Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to act upstream of or within regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of transcription regulator complex. Orthologous to human E2F8 (E2F transcription factor 8). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See e2f8 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 4 NC_030680.2 (4248487..4259190, complement)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) Unplaced Scaffold NW_016683577.1 (84575..94959)

    Chromosome 4 - NC_030680.2Genomic Context describing neighboring genes Neighboring gene zinc finger DHHC-type containing 13 Neighboring gene cysteine and glycine rich protein 3 Neighboring gene neuron navigator 2 Neighboring gene developing brain homeobox 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of transcription regulator complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    transcription factor E2F8

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030680.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      4248487..4259190 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_004913337.4 → XP_004913394.1  transcription factor E2F8

      See identical proteins and their annotated locations for XP_004913394.1

      UniProtKB/Swiss-Prot
      F7EA39
      UniProtKB/TrEMBL
      A0A1B8Y1F7
      Related
      ENSXETP00000104009.1, ENSXETT00000123605.1
      Conserved Domains (2) summary
      PRK12323
      Location:445 → 523
      PRK12323; DNA polymerase III subunit gamma/tau
      pfam02319
      Location:99 → 167
      E2F_TDP; E2F/DP family winged-helix DNA-binding domain

    2. XM_002942835.5 → XP_002942881.1  transcription factor E2F8

      See identical proteins and their annotated locations for XP_002942881.1

      UniProtKB/Swiss-Prot
      F7EA39
      UniProtKB/TrEMBL
      A0A1B8Y1F7
      Related
      ENSXETP00000009660.4, ENSXETT00000009660.5
      Conserved Domains (2) summary
      PRK12323
      Location:445 → 523
      PRK12323; DNA polymerase III subunit gamma/tau
      pfam02319
      Location:99 → 167
      E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    Nucleotide Protein Strain
    Heading Accession and Version

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