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    tp53rk TP53 regulating kinase [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 100127196, updated on 4-Nov-2024

    Summary

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    Official Symbol
    tp53rkprovided by Xenbase
    Official Full Name
    TP53 regulating kinaseprovided by Xenbase
    Primary source
    Xenbase:XB-GENE-484888
    See related
    Ensembl:ENSXETG00000003469 AllianceGenome:Xenbase:XB-GENE-484888
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Also known as
    prpk; Bud32; nori-2; nori-2p
    Summary
    Predicted to enable ATP binding activity and histone H2AS1 kinase activity. Predicted to act upstream of or within protein phosphorylation and tRNA processing. Human ortholog(s) of this gene implicated in Galloway-Mowat syndrome 4. Orthologous to human TP53RK (TP53 regulating kinase). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See tp53rk in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 10 NC_030686.2 (37656093..37657815)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 10 NC_030686.1 (29399120..29400839)

    Chromosome 10 - NC_030686.2Genomic Context describing neighboring genes Neighboring gene EYA transcriptional coactivator and phosphatase 2 Neighboring gene solute carrier family 2 (facilitated glucose transporter), member 10 Neighboring gene Ig mu chain C region-like Neighboring gene uncharacterized LOC116407943

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables histone H2AS1 kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within tRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    EKC/KEOPS complex subunit TP53RK

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030686.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      37656093..37657815
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002933159.5 → XP_002933205.2  EKC/KEOPS complex subunit TP53RK

      UniProtKB/TrEMBL
      A9JTT7, F6ZWY1
      Related
      ENSXETP00000112196.1, ENSXETT00000109040.1
      Conserved Domains (1) summary
      COG3642
      Location:20 → 237
      Bud32; tRNA A-37 threonylcarbamoyl transferase component Bud32 [Translation, ribosomal structure and biogenesis]
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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    Research Materials