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    tinagl1 tubulointerstitial nephritis antigen-like 1 [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 100124858, updated on 4-Nov-2024

    Summary

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    Official Symbol
    tinagl1provided by Xenbase
    Official Full Name
    tubulointerstitial nephritis antigen-like 1provided by Xenbase
    Primary source
    Xenbase:XB-GENE-991634
    See related
    Ensembl:ENSXETG00000017634 AllianceGenome:Xenbase:XB-GENE-991634
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Summary
    Predicted to enable cysteine-type peptidase activity and peptidase inhibitor activity. Predicted to act upstream of or within proteolysis. Predicted to be located in extracellular region. Orthologous to human TINAGL1 (tubulointerstitial nephritis antigen like 1). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See tinagl1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 2 NC_030678.2 (87681676..87715763, complement)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 2 NC_030678.1 (83543480..83577699, complement)

    Chromosome 2 - NC_030678.2Genomic Context describing neighboring genes Neighboring gene collagen, type XVI, alpha 1 Neighboring gene penta-EF-hand domain containing 1 Neighboring gene regulating synaptic membrane exocytosis 3 Neighboring gene nuclear transcription factor Y subunit gamma Neighboring gene microRNA mir-30e

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables cysteine-type peptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables peptidase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    tubulointerstitial nephritis antigen-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030678.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      87681676..87715763 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002938486.5 → XP_002938532.3  tubulointerstitial nephritis antigen-like

      UniProtKB/TrEMBL
      A4IHK5, F6U204
      Related
      ENSXETP00000038292.4, ENSXETT00000038292.4
      Conserved Domains (2) summary
      smart00215
      Location:104 → 139
      VWC_out; von Willebrand factor (vWF) type C domain
      cd02620
      Location:202 → 451
      Peptidase_C1A_CathepsinB; Cathepsin B group; composed of cathepsin B and similar proteins, including tubulointerstitial nephritis antigen (TIN-Ag). Cathepsin B is a lysosomal papain-like cysteine peptidase which is expressed in all tissues and functions primarily as an ...

    2. XM_004911603.3 → XP_004911660.2  tubulointerstitial nephritis antigen-like

      UniProtKB/TrEMBL
      A4IHK5, F6U204
      Conserved Domains (2) summary
      smart00215
      Location:104 → 139
      VWC_out; von Willebrand factor (vWF) type C domain
      cd02620
      Location:202 → 451
      Peptidase_C1A_CathepsinB; Cathepsin B group; composed of cathepsin B and similar proteins, including tubulointerstitial nephritis antigen (TIN-Ag). Cathepsin B is a lysosomal papain-like cysteine peptidase which is expressed in all tissues and functions primarily as an ...
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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